6YPT

X-ray structure of Turnip Yellow Mosaic Virus PRO/DUB in complex with Ubiquitin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004197	molecular_function	cysteine-type endopeptidase activity
A	0016032	biological_process	viral process
C	0004197	molecular_function	cysteine-type endopeptidase activity
C	0016032	biological_process	viral process

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue GVE A 901

Chain	Residue
A	LEU781
A	CYS783
A	LEU820
A	SER868
A	HIS869
B	GLY75

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site_id	AC2
Number of Residues	9
Details	binding site for Di-peptide GVE C 901 and GLY D 75

Chain	Residue
C	GLY821
C	LEU822
C	SER868
C	HIS869
C	PHE870
D	ARG74
C	LEU781
C	CYS783
C	LEU820

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site_id	AC3
Number of Residues	11
Details	binding site for Di-peptide GVE C 901 and CYS C 783

Chain	Residue
C	LEU781
C	ASN782
C	LEU784
C	LEU785
C	SER786
C	ALA787
C	LEU820
C	SER868
C	HIS869
C	PHE870
D	GLY75

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Functional Information from PROSITE/UniProt

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
B	LYS27-ASP52

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: For protease activity => ECO:0000255|PROSITE-ProRule:PRU01074, ECO:0000269|PubMed:23966860, ECO:0000269|PubMed:29117247

Chain	Residue	Details
A	CYS783
A	HIS869
C	CYS783
C	HIS869

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site_id	SWS_FT_FI2
Number of Residues	2
Details	SITE: Cleavage; by viral protease => ECO:0000269|PubMed:17686855

Chain	Residue	Details
A	SER879
C	SER879

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