6YPR

Human histidine triad nucleotide-binding protein 2 (hHINT2) refined to 1.26 A in H32 space group

This is a non-PDB format compatible entry.

Replaces:  4NJY

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0000166	molecular_function	nucleotide binding
AAA	0003824	molecular_function	catalytic activity
AAA	0005515	molecular_function	protein binding
AAA	0005737	cellular_component	cytoplasm
AAA	0005739	cellular_component	mitochondrion
AAA	0005741	cellular_component	mitochondrial outer membrane
AAA	0006694	biological_process	steroid biosynthetic process
AAA	0006915	biological_process	apoptotic process
AAA	0016042	biological_process	lipid catabolic process
AAA	0016787	molecular_function	hydrolase activity
AAA	0043530	molecular_function	adenosine 5'-monophosphoramidase activity
AAA	2000757	biological_process	negative regulation of peptidyl-lysine acetylation

Functional Information from PROSITE/UniProt

site_id	PS00892
Number of Residues	19
Details	HIT_1 HIT domain signature. NdgklGaQsVyHLHIHVLG

Chain	Residue	Details
AAA	ASN136-GLY154

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Tele-AMP-histidine intermediate => ECO:0000269|PubMed:16762638

Chain	Residue	Details
AAA	HIS149

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site_id	SWS_FT_FI2
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:23659632, ECO:0007744|PDB:4INI

Chain	Residue	Details
AAA	SER63
AAA	ASP80
AAA	ASN136
AAA	ALA142
AAA	HIS149

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site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q9D0S9

Chain	Residue	Details
AAA	LYS119
AAA	LYS139

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