Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004674 | molecular_function | protein serine/threonine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue ADP B 401 |
| Chain | Residue |
| B | SER51 |
| B | MET163 |
| B | ILE174 |
| B | ASP175 |
| B | MG404 |
| B | MG405 |
| B | PO4406 |
| B | HOH525 |
| B | HOH539 |
| B | HOH550 |
| B | HOH568 |
| B | VAL53 |
| B | HOH647 |
| B | VAL66 |
| B | LYS68 |
| B | ILE95 |
| B | GLU114 |
| B | VAL116 |
| B | HIS160 |
| B | ASN161 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ACT B 402 |
| Chain | Residue |
| B | LYS158 |
| B | HIS160 |
| B | PO4406 |
| B | HOH525 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue ADP B 403 |
| Chain | Residue |
| B | TYR50 |
| B | LYS77 |
| B | ARG80 |
| B | ARG155 |
| B | LEU178 |
| B | ASN189 |
| B | ARG191 |
| B | PO4406 |
| B | HOH503 |
| B | HOH532 |
| B | HOH566 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 404 |
| Chain | Residue |
| B | ASN161 |
| B | ASP175 |
| B | ADP401 |
| B | PO4406 |
| B | HOH525 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 405 |
| Chain | Residue |
| B | ASP175 |
| B | ADP401 |
| B | PO4406 |
| B | HOH505 |
| B | HOH532 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | binding site for residue PO4 B 406 |
| Chain | Residue |
| B | ASP156 |
| B | LYS158 |
| B | ASN161 |
| B | ASP175 |
| B | SER194 |
| B | ADP401 |
| B | ACT402 |
| B | ADP403 |
| B | MG404 |
| B | MG405 |
| B | HOH502 |
| B | HOH505 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGRGKYSEVFeAinitnnek..........VVVK |
| Chain | Residue | Details |
| B | LEU45-LYS68 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ImHrDVKphNVMI |
| Chain | Residue | Details |
| B | ILE152-ILE164 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 285 |
| Details | Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | Region: {"description":"Interaction with beta subunit","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
