6YPA

The C146A variant of an amidase from Pyrococcus horikoshii with bound glutaramide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003837	molecular_function	beta-ureidopropionase activity
A	0006807	biological_process	obsolete nitrogen compound metabolic process
A	0016787	molecular_function	hydrolase activity
A	0033388	biological_process	putrescine biosynthetic process from arginine
A	0033396	biological_process	beta-alanine biosynthetic process via 3-ureidopropionate
A	0050126	molecular_function	N-carbamoylputrescine amidase activity
B	0003837	molecular_function	beta-ureidopropionase activity
B	0006807	biological_process	obsolete nitrogen compound metabolic process
B	0016787	molecular_function	hydrolase activity
B	0033388	biological_process	putrescine biosynthetic process from arginine
B	0033396	biological_process	beta-alanine biosynthetic process via 3-ureidopropionate
B	0050126	molecular_function	N-carbamoylputrescine amidase activity
C	0003837	molecular_function	beta-ureidopropionase activity
C	0006807	biological_process	obsolete nitrogen compound metabolic process
C	0016787	molecular_function	hydrolase activity
C	0033388	biological_process	putrescine biosynthetic process from arginine
C	0033396	biological_process	beta-alanine biosynthetic process via 3-ureidopropionate
C	0050126	molecular_function	N-carbamoylputrescine amidase activity
D	0003837	molecular_function	beta-ureidopropionase activity
D	0006807	biological_process	obsolete nitrogen compound metabolic process
D	0016787	molecular_function	hydrolase activity
D	0033388	biological_process	putrescine biosynthetic process from arginine
D	0033396	biological_process	beta-alanine biosynthetic process via 3-ureidopropionate
D	0050126	molecular_function	N-carbamoylputrescine amidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue P6W A 301

Chain	Residue
A	GLU42
A	LEU172
A	VAL173
A	MET174
A	HOH407
A	TYR48
A	LYS113
A	PHE117
A	GLU120
A	ALA146
A	PHE147
A	TRP149
A	ASN171

---

site_id	AC2
Number of Residues	9
Details	binding site for residue GOL A 302

Chain	Residue
A	PRO178
A	ARG179
A	LYS209
A	VAL219
A	ILE222
A	HOH418
A	HOH429
D	THR226
D	GLU227

---

site_id	AC3
Number of Residues	13
Details	binding site for residue P6W B 301

Chain	Residue
B	GLU42
B	TYR48
B	LYS113
B	PHE117
B	GLU120
B	ALA146
B	PHE147
B	TRP149
B	ASN171
B	LEU172
B	VAL173
B	MET174
B	HOH407

---

site_id	AC4
Number of Residues	12
Details	binding site for residue P6W C 301

Chain	Residue
C	GLU42
C	LYS113
C	PHE117
C	GLU120
C	ALA146
C	PHE147
C	TRP149
C	ASN171
C	LEU172
C	VAL173
C	MET174
C	HOH415

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site_id	AC5
Number of Residues	13
Details	binding site for residue P6W D 301

Chain	Residue
D	GLU42
D	TYR48
D	LYS113
D	PHE117
D	GLU120
D	ALA146
D	PHE147
D	TRP149
D	ASN171
D	LEU172
D	VAL173
D	MET174
D	HOH511

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