Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0002161 | molecular_function | aminoacyl-tRNA editing activity |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004823 | molecular_function | leucine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006412 | biological_process | translation |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006429 | biological_process | leucyl-tRNA aminoacylation |
| A | 0106074 | biological_process | aminoacyl-tRNA metabolism involved in translational fidelity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue OW5 A 1101 |
| Chain | Residue |
| A | MET40 |
| A | ASP80 |
| A | TYR513 |
| A | GLY543 |
| A | GLY544 |
| A | GLU546 |
| A | HIS547 |
| A | HIS551 |
| A | MET582 |
| A | VAL583 |
| A | LYS634 |
| A | PHE41 |
| A | MET635 |
| A | HOH1284 |
| A | PRO42 |
| A | TYR43 |
| A | HIS49 |
| A | GLY51 |
| A | HIS52 |
| A | ASN55 |
| A | TYR56 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 1102 |
| Chain | Residue |
| A | TRP223 |
| A | LEU429 |
| A | ARG430 |
| A | ASP431 |
| A | TRP432 |
| A | TYR554 |
| A | HOH1231 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 1103 |
| Chain | Residue |
| A | TRP223 |
| A | GLU301 |
| A | TYR339 |
| A | ARG428 |
| A | HOH1231 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1104 |
| Chain | Residue |
| A | CYS449 |
| A | CYS452 |
| A | CYS490 |
| A | CYS493 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1105 |
| Chain | Residue |
| A | GLU210 |
| A | HOH1286 |
| A | HOH1310 |
| A | HOH1389 |
| A | HOH1390 |
| A | HOH1406 |
Functional Information from PROSITE/UniProt
| site_id | PS00178 |
| Number of Residues | 12 |
| Details | AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. PypSGkLHMGHV |
| Chain | Residue | Details |
| A | PRO42-VAL53 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | LYS637 | |
