6YJZ
Crystal structure of mouse pyridoxal kinase in apo form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0008478 | molecular_function | pyridoxal kinase activity |
| A | 0009443 | biological_process | pyridoxal 5'-phosphate salvage |
| A | 0016773 | molecular_function | phosphotransferase activity, alcohol group as acceptor |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0030955 | molecular_function | potassium ion binding |
| A | 0031402 | molecular_function | sodium ion binding |
| A | 0031403 | molecular_function | lithium ion binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0042816 | biological_process | vitamin B6 metabolic process |
| A | 0070280 | molecular_function | pyridoxal binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005654 | cellular_component | nucleoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0008478 | molecular_function | pyridoxal kinase activity |
| B | 0009443 | biological_process | pyridoxal 5'-phosphate salvage |
| B | 0016773 | molecular_function | phosphotransferase activity, alcohol group as acceptor |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0030955 | molecular_function | potassium ion binding |
| B | 0031402 | molecular_function | sodium ion binding |
| B | 0031403 | molecular_function | lithium ion binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0042816 | biological_process | vitamin B6 metabolic process |
| B | 0070280 | molecular_function | pyridoxal binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005654 | cellular_component | nucleoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0008478 | molecular_function | pyridoxal kinase activity |
| C | 0009443 | biological_process | pyridoxal 5'-phosphate salvage |
| C | 0016773 | molecular_function | phosphotransferase activity, alcohol group as acceptor |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0030955 | molecular_function | potassium ion binding |
| C | 0031402 | molecular_function | sodium ion binding |
| C | 0031403 | molecular_function | lithium ion binding |
| C | 0042803 | molecular_function | protein homodimerization activity |
| C | 0042816 | biological_process | vitamin B6 metabolic process |
| C | 0070280 | molecular_function | pyridoxal binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005654 | cellular_component | nucleoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0008478 | molecular_function | pyridoxal kinase activity |
| D | 0009443 | biological_process | pyridoxal 5'-phosphate salvage |
| D | 0016773 | molecular_function | phosphotransferase activity, alcohol group as acceptor |
| D | 0030170 | molecular_function | pyridoxal phosphate binding |
| D | 0030955 | molecular_function | potassium ion binding |
| D | 0031402 | molecular_function | sodium ion binding |
| D | 0031403 | molecular_function | lithium ion binding |
| D | 0042803 | molecular_function | protein homodimerization activity |
| D | 0042816 | biological_process | vitamin B6 metabolic process |
| D | 0070280 | molecular_function | pyridoxal binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue PG4 A 401 |
| Chain | Residue |
| A | TRP52 |
| A | TYR84 |
| A | ARG86 |
| A | HOH528 |
| B | VAL306 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | CYS5 |
| A | LEU31 |
| A | GLY32 |
| A | HIS246 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | ASP113 |
| A | TYR127 |
| A | THR148 |
| A | ASN150 |
| A | GLU153 |
| A | THR186 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue PG4 A 405 |
| Chain | Residue |
| A | THR186 |
| A | VAL226 |
| A | THR233 |
| A | GLY234 |
| A | GLN264 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 406 |
| Chain | Residue |
| A | GLN55 |
| A | VAL56 |
| A | LYS58 |
| A | GLU61 |
| A | HOH545 |
| B | LYS58 |
| B | GLU61 |
| B | GLN194 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 407 |
| Chain | Residue |
| A | TYR66 |
| A | GLU67 |
| A | LYS70 |
| A | GLU100 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 408 |
| Chain | Residue |
| A | ASN39 |
| A | VAL41 |
| A | GLN42 |
| B | ASN39 |
| B | GLN42 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue EDO B 501 |
| Chain | Residue |
| B | ARG6 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 502 |
| Chain | Residue |
| B | GLU4 |
| B | LEU31 |
| B | GLY32 |
| B | PHE33 |
| B | HIS246 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| B | ASP113 |
| B | THR148 |
| B | ASN150 |
| B | GLU153 |
| B | THR186 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 504 |
| Chain | Residue |
| B | HIS63 |
| B | GLU100 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 505 |
| Chain | Residue |
| B | SER12 |
| B | HIS46 |
| B | THR47 |
| B | TYR84 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 701 |
| Chain | Residue |
| C | GLU4 |
| C | LEU31 |
| C | PHE33 |
| C | HIS246 |
| site_id | AD5 |
| Number of Residues | 1 |
| Details | binding site for residue EDO C 702 |
| Chain | Residue |
| C | LYS119 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 703 |
| Chain | Residue |
| C | GLU155 |
| C | GLY159 |
| C | LYS161 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO C 704 |
| Chain | Residue |
| C | PHE43 |
| C | THR47 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 705 |
| Chain | Residue |
| C | SER40 |
| C | VAL56 |
| C | LEU57 |
| C | THR85 |
| C | PHE90 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 706 |
| Chain | Residue |
| C | HIS63 |
| C | TYR66 |
| C | GLU67 |
| C | GLU100 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 401 |
| Chain | Residue |
| D | GLU4 |
| D | CYS5 |
| D | LEU31 |
| D | GLY32 |
| D | HIS246 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 402 |
| Chain | Residue |
| D | ARG6 |
| D | LYS76 |
| D | ASP78 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"O00764","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 56 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"O00764","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21183079","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"O00764","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
