Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6YJ4

Structure of Yarrowia lipolytica complex I at 2.7 A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005739	cellular_component	mitochondrion
A	0005747	cellular_component	mitochondrial respiratory chain complex I
A	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A	0016020	cellular_component	membrane
A	0031966	cellular_component	mitochondrial membrane
A	0055085	biological_process	transmembrane transport
A	0070469	cellular_component	respirasome
B	0005747	cellular_component	mitochondrial respiratory chain complex I
B	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
B	0009060	biological_process	aerobic respiration
B	0015990	biological_process	electron transport coupled proton transport
B	0016491	molecular_function	oxidoreductase activity
B	0032981	biological_process	mitochondrial respiratory chain complex I assembly
B	0046872	molecular_function	metal ion binding
B	0048038	molecular_function	quinone binding
B	0051536	molecular_function	iron-sulfur cluster binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
B	0055085	biological_process	transmembrane transport
C	0005747	cellular_component	mitochondrial respiratory chain complex I
C	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
C	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
C	0055085	biological_process	transmembrane transport
D	0005747	cellular_component	mitochondrial respiratory chain complex I
D	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
D	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
D	0048038	molecular_function	quinone binding
D	0051287	molecular_function	NAD binding
E	0003954	molecular_function	NADH dehydrogenase activity
E	0005747	cellular_component	mitochondrial respiratory chain complex I
E	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
E	0016491	molecular_function	oxidoreductase activity
E	0045271	cellular_component	respiratory chain complex I
E	0046872	molecular_function	metal ion binding
E	0051536	molecular_function	iron-sulfur cluster binding
E	0051537	molecular_function	2 iron, 2 sulfur cluster binding
F	0003954	molecular_function	NADH dehydrogenase activity
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0005747	cellular_component	mitochondrial respiratory chain complex I
F	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
F	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
F	0010181	molecular_function	FMN binding
F	0016020	cellular_component	membrane
F	0045271	cellular_component	respiratory chain complex I
F	0046872	molecular_function	metal ion binding
F	0051287	molecular_function	NAD binding
F	0051536	molecular_function	iron-sulfur cluster binding
F	0051539	molecular_function	4 iron, 4 sulfur cluster binding
F	0055085	biological_process	transmembrane transport
F	0070469	cellular_component	respirasome
G	0003954	molecular_function	NADH dehydrogenase activity
G	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
G	0016020	cellular_component	membrane
G	0016491	molecular_function	oxidoreductase activity
G	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
G	0042773	biological_process	ATP synthesis coupled electron transport
G	0045333	biological_process	cellular respiration
G	0051536	molecular_function	iron-sulfur cluster binding
G	0051539	molecular_function	4 iron, 4 sulfur cluster binding
G	0055085	biological_process	transmembrane transport
H	0003954	molecular_function	NADH dehydrogenase activity
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0005747	cellular_component	mitochondrial respiratory chain complex I
H	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
H	0009060	biological_process	aerobic respiration
H	0016020	cellular_component	membrane
H	0055085	biological_process	transmembrane transport
H	0070469	cellular_component	respirasome
I	0003954	molecular_function	NADH dehydrogenase activity
I	0005739	cellular_component	mitochondrion
I	0005747	cellular_component	mitochondrial respiratory chain complex I
I	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
I	0016020	cellular_component	membrane
I	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
I	0032981	biological_process	mitochondrial respiratory chain complex I assembly
I	0051539	molecular_function	4 iron, 4 sulfur cluster binding
J	0005739	cellular_component	mitochondrion
J	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
J	0016020	cellular_component	membrane
J	0031966	cellular_component	mitochondrial membrane
J	0055085	biological_process	transmembrane transport
J	0070469	cellular_component	respirasome
K	0005739	cellular_component	mitochondrion
K	0005747	cellular_component	mitochondrial respiratory chain complex I
K	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
K	0016020	cellular_component	membrane
K	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
K	0031966	cellular_component	mitochondrial membrane
K	0042773	biological_process	ATP synthesis coupled electron transport
K	0055085	biological_process	transmembrane transport
K	0070469	cellular_component	respirasome
L	0003954	molecular_function	NADH dehydrogenase activity
L	0005739	cellular_component	mitochondrion
L	0005743	cellular_component	mitochondrial inner membrane
L	0005747	cellular_component	mitochondrial respiratory chain complex I
L	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
L	0015990	biological_process	electron transport coupled proton transport
L	0016020	cellular_component	membrane
L	0042773	biological_process	ATP synthesis coupled electron transport
L	0070469	cellular_component	respirasome
M	0003954	molecular_function	NADH dehydrogenase activity
M	0005739	cellular_component	mitochondrion
M	0005747	cellular_component	mitochondrial respiratory chain complex I
M	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
M	0009060	biological_process	aerobic respiration
M	0015990	biological_process	electron transport coupled proton transport
M	0016020	cellular_component	membrane
M	0031966	cellular_component	mitochondrial membrane
M	0042773	biological_process	ATP synthesis coupled electron transport
M	0045271	cellular_component	respiratory chain complex I
M	0048039	molecular_function	ubiquinone binding
M	0070469	cellular_component	respirasome
N	0005739	cellular_component	mitochondrion
N	0005743	cellular_component	mitochondrial inner membrane
N	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
N	0016020	cellular_component	membrane
N	0055085	biological_process	transmembrane transport
N	0070469	cellular_component	respirasome
O	0005747	cellular_component	mitochondrial respiratory chain complex I
O	0016020	cellular_component	membrane
P	0005739	cellular_component	mitochondrion
P	0044877	molecular_function	protein-containing complex binding
P	1901006	biological_process	ubiquinone-6 biosynthetic process
Q	0005739	cellular_component	mitochondrion
Q	0005743	cellular_component	mitochondrial inner membrane
Q	0005747	cellular_component	mitochondrial respiratory chain complex I
Q	0016020	cellular_component	membrane
Q	0022900	biological_process	electron transport chain
Q	0070469	cellular_component	respirasome
R	0005747	cellular_component	mitochondrial respiratory chain complex I
R	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
S	0005739	cellular_component	mitochondrion
S	0005743	cellular_component	mitochondrial inner membrane
S	0005747	cellular_component	mitochondrial respiratory chain complex I
S	0070469	cellular_component	respirasome
T	0000035	molecular_function	acyl binding
T	0000036	molecular_function	acyl carrier activity
T	0005739	cellular_component	mitochondrion
T	0005747	cellular_component	mitochondrial respiratory chain complex I
T	0006629	biological_process	lipid metabolic process
T	0006631	biological_process	fatty acid metabolic process
T	0006633	biological_process	fatty acid biosynthetic process
T	0009107	biological_process	lipoate biosynthetic process
T	0016226	biological_process	iron-sulfur cluster assembly
T	0099128	cellular_component	mitochondrial iron-sulfur cluster assembly complex
U	0000035	molecular_function	acyl binding
U	0000036	molecular_function	acyl carrier activity
U	0005739	cellular_component	mitochondrion
U	0005747	cellular_component	mitochondrial respiratory chain complex I
U	0006629	biological_process	lipid metabolic process
U	0006631	biological_process	fatty acid metabolic process
U	0006633	biological_process	fatty acid biosynthetic process
V	0005739	cellular_component	mitochondrion
V	0005743	cellular_component	mitochondrial inner membrane
V	0005747	cellular_component	mitochondrial respiratory chain complex I
V	0016020	cellular_component	membrane
V	0022904	biological_process	respiratory electron transport chain
W	0005739	cellular_component	mitochondrion
W	0005743	cellular_component	mitochondrial inner membrane
W	0005747	cellular_component	mitochondrial respiratory chain complex I
W	0006979	biological_process	response to oxidative stress
W	0016020	cellular_component	membrane
W	0070469	cellular_component	respirasome
X	0005739	cellular_component	mitochondrion
X	0005743	cellular_component	mitochondrial inner membrane
X	0005747	cellular_component	mitochondrial respiratory chain complex I
X	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
X	0016020	cellular_component	membrane
X	0070469	cellular_component	respirasome
Y	0005739	cellular_component	mitochondrion
Y	0005743	cellular_component	mitochondrial inner membrane
Y	0005744	cellular_component	TIM23 mitochondrial import inner membrane translocase complex
Y	0005747	cellular_component	mitochondrial respiratory chain complex I
Y	0008320	molecular_function	protein transmembrane transporter activity
Y	0016020	cellular_component	membrane
Y	0030150	biological_process	protein import into mitochondrial matrix
Y	0032981	biological_process	mitochondrial respiratory chain complex I assembly
Z	0005739	cellular_component	mitochondrion
Z	0005743	cellular_component	mitochondrial inner membrane
Z	0005747	cellular_component	mitochondrial respiratory chain complex I
Z	0016020	cellular_component	membrane
Z	0070469	cellular_component	respirasome
a	0005739	cellular_component	mitochondrion
a	0005743	cellular_component	mitochondrial inner membrane
a	0005747	cellular_component	mitochondrial respiratory chain complex I
a	0016020	cellular_component	membrane
a	0070469	cellular_component	respirasome
b	0016020	cellular_component	membrane
e	0005739	cellular_component	mitochondrion
e	0005743	cellular_component	mitochondrial inner membrane
e	0005747	cellular_component	mitochondrial respiratory chain complex I
e	0005758	cellular_component	mitochondrial intermembrane space
e	0016020	cellular_component	membrane
e	0032981	biological_process	mitochondrial respiratory chain complex I assembly
e	0070469	cellular_component	respirasome
f	0005739	cellular_component	mitochondrion
f	0005743	cellular_component	mitochondrial inner membrane
f	0005747	cellular_component	mitochondrial respiratory chain complex I
f	0006979	biological_process	response to oxidative stress
f	0016020	cellular_component	membrane
f	0032981	biological_process	mitochondrial respiratory chain complex I assembly
f	0070469	cellular_component	respirasome
i	0016020	cellular_component	membrane
k	0005739	cellular_component	mitochondrion
k	0005743	cellular_component	mitochondrial inner membrane
k	0005747	cellular_component	mitochondrial respiratory chain complex I
k	0016020	cellular_component	membrane
k	0022900	biological_process	electron transport chain
k	0032981	biological_process	mitochondrial respiratory chain complex I assembly
k	0070469	cellular_component	respirasome
l	0005739	cellular_component	mitochondrion
l	0005747	cellular_component	mitochondrial respiratory chain complex I
l	0016020	cellular_component	membrane
m	0016020	cellular_component	membrane
n	0005739	cellular_component	mitochondrion
n	0005743	cellular_component	mitochondrial inner membrane
n	0005747	cellular_component	mitochondrial respiratory chain complex I
n	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
n	0016020	cellular_component	membrane
n	0070469	cellular_component	respirasome
o	0005739	cellular_component	mitochondrion
o	0005743	cellular_component	mitochondrial inner membrane
o	0005747	cellular_component	mitochondrial respiratory chain complex I
o	0005758	cellular_component	mitochondrial intermembrane space
o	0016020	cellular_component	membrane
p	0005739	cellular_component	mitochondrion
p	0005743	cellular_component	mitochondrial inner membrane
p	0005747	cellular_component	mitochondrial respiratory chain complex I
p	0016020	cellular_component	membrane
p	0070469	cellular_component	respirasome

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue 3PE A 501

Chain	Residue
A	ASN2
A	PHE4
H	LEU102
H	ASN103
J	TYR48
J	GLY53

site_id	AC2
Number of Residues	11
Details	binding site for residue 3PE A 502

Chain	Residue
A	LYS29
B	ILE203
B	TRP207
P	GLU86
P	LYS211
P	TRP306
P	PLC401
P	CDL403
A	LEU24
A	ALA26
A	VAL27

site_id	AC3
Number of Residues	9
Details	binding site for residue SF4 B 301

Chain	Residue
B	CYS85
B	CYS86
B	GLY148
B	SER149
B	CYS150
B	CYS180
B	PRO181
D	2MR121
D	ARG141

site_id	AC4
Number of Residues	13
Details	binding site for residue LMT B 302

Chain	Residue
B	SER94
B	ASP101
B	HOH413
D	LEU204
H	THR23
H	ARG36
H	ALA50
H	ASP53
H	PHE228
H	LEU229
H	TYR232
H	ARG297
H	HOH706

site_id	AC5
Number of Residues	8
Details	binding site for residue PLC D 501

Chain	Residue
D	ALA36
D	GLY38
L	GLY588
L	PRO589
L	ILE592
M	GLU161
M	TYR166
M	PHE170

site_id	AC6
Number of Residues	8
Details	binding site for residue FES E 301

Chain	Residue
E	CYS127
E	THR129
E	PRO131
E	CYS132
E	CYS168
E	LEU169
E	ALA171
E	CYS172

site_id	AC7
Number of Residues	16
Details	binding site for residue FMN F 501

Chain	Residue
F	GLY86
F	ARG87
F	GLY88
F	LYS97
F	ASN118
F	ASP120
F	GLU121
F	GLY122
F	TYR206
F	GLY209
F	GLU210
F	GLU211
F	VAL244
F	THR245
F	ASN246
F	THR249

site_id	AC8
Number of Residues	6
Details	binding site for residue SF4 F 502

Chain	Residue
F	SER380
F	CYS381
F	GLN383
F	CYS384
F	CYS387
F	CYS427

site_id	AC9
Number of Residues	9
Details	binding site for residue SF4 G 801

Chain	Residue
G	HIS129
G	PRO130
G	ASP132
G	CYS133
G	CYS136
G	GLY139
G	CYS142
G	VAL235
G	GLY236

site_id	AD1
Number of Residues	8
Details	binding site for residue SF4 G 802

Chain	Residue
G	MET180
G	CYS183
G	ILE184
G	CYS186
G	THR187
G	CYS189
G	CYS233
G	VAL235

site_id	AD2
Number of Residues	7
Details	binding site for residue FES G 803

Chain	Residue
G	CYS83
G	CYS97
G	CYS69
G	TYR70
G	GLY78
G	CYS80
G	ARG81

site_id	AD3
Number of Residues	8
Details	binding site for residue PLC H 601

Chain	Residue
B	TRP70
H	PHE41
H	VAL42
H	GLY43
H	TYR44
H	LEU48
f	LEU24
f	ASN25

site_id	AD4
Number of Residues	2
Details	binding site for residue 3PE H 602

Chain	Residue
H	TRP177
H	ASN254

site_id	AD5
Number of Residues	9
Details	binding site for residue 3PE I 6301

Chain	Residue
D	ARG269
H	PRO184
H	PHE303
H	PHE311
I	THR75
I	TYR77
I	PHE78
I	PHE84
Z	LEU34

site_id	AD6
Number of Residues	9
Details	binding site for residue SF4 I 6302

Chain	Residue
I	HIS118
I	CYS140
I	CYS169
I	ILE170
I	TYR171
I	CYS172
I	GLY173
I	CYS175
I	GLU186

site_id	AD7
Number of Residues	9
Details	binding site for residue SF4 I 6303

Chain	Residue
I	CYS130
I	ILE131
I	CYS133
I	LYS134
I	CYS136
I	TYR162
I	CYS179
I	VAL181
I	ILE184

site_id	AD8
Number of Residues	8
Details	binding site for residue PLC L 1001

Chain	Residue
L	ILE296
L	LYS431
L	ASN529
L	PHE536
L	ILE543
L	TYR547
n	TRP29
n	SER31

site_id	AD9
Number of Residues	7
Details	binding site for residue PLC L 1002

Chain	Residue
L	PHE278
L	TRP282
L	SER410
l	PHE105
l	SER108
l	THR112
l	TYR113

site_id	AE1
Number of Residues	12
Details	binding site for residue 3PE L 1003

Chain	Residue
L	GLN162
L	LYS165
L	SER166
L	LEU168
L	SER169
L	LEU172
L	LEU238
L	ASN561
L	ILE565
M	ILE422
l	PRO82
l	ASP83

site_id	AE2
Number of Residues	15
Details	binding site for residue 3PE L 1004

Chain	Residue
L	ARG586
L	GLY591
L	ARG594
L	LEU595
L	LYS598
L	ILE643
L	LEU650
L	TYR651
L	PHE654
L	SER655
L	3PE1006
Y	TRP121
Y	LEU124
Y	PHE132
Y	PHE139

site_id	AE3
Number of Residues	15
Details	binding site for residue 3PE L 1005

Chain	Residue
L	ASN602
L	LEU606
L	LEU620
L	ILE623
L	SER627
L	LEU630
L	LEU646
L	ILE652
L	LEU653
N	PRO216
N	ILE262
N	ILE265
Y	ALA43
Y	ARG47
Y	LEU50

site_id	AE4
Number of Residues	6
Details	binding site for residue 3PE L 1006

Chain	Residue
L	ARG586
L	3PE1004
Y	PRO116
Y	ALA117
Y	GLY120
m	TYR48

site_id	AE5
Number of Residues	9
Details	binding site for residue PLC L 1007

Chain	Residue
L	HIS112
L	ARG115
M	THR366
M	THR367
M	THR374
M	ILE377
i	SER14
i	THR16
i	GLY18

site_id	AE6
Number of Residues	15
Details	binding site for residue CDL M 501

Chain	Residue
L	PHE21
M	THR87
M	GLN371
M	TYR375
M	LYS451
M	ASN455
M	ILE456
M	ILE458
g	TYR169
g	ALA173
g	MET183
h	LYS53
h	TRP54
h	VAL62
i	MET15

site_id	AE7
Number of Residues	3
Details	binding site for residue 3PE M 502

Chain	Residue
M	ASN110
M	LEU113
N	TYR359

site_id	AE8
Number of Residues	4
Details	binding site for residue LMT M 503

Chain	Residue
M	ASN56
M	LEU68
M	TRP130
M	3PE504

site_id	AE9
Number of Residues	6
Details	binding site for residue 3PE M 504

Chain	Residue
M	PHE38
M	LEU42
M	LEU68
M	SER136
M	LEU140
M	LMT503

site_id	AF1
Number of Residues	6
Details	binding site for residue PLC N 2401

Chain	Residue
N	TYR67
N	MET70
N	ILE460
N	ILE463
N	PHE468
d	LEU50

site_id	AF2
Number of Residues	12
Details	binding site for residue 3PE N 2402

Chain	Residue
J	SER107
J	LEU118
K	LEU8
K	PHE12
L	VAL632
N	LEU167
N	ASN198
N	LEU199
N	ILE202
N	SER257
N	LEU258
N	VAL259

site_id	AF3
Number of Residues	15
Details	binding site for residue CDL O 401

Chain	Residue
A	ASN85
A	TYR86
A	PHE88
H	TYR332
J	PHE160
J	VAL164
N	ILE3
O	HIS27
O	LYS29
O	SER129
O	SER130
O	PRO154
O	PHE158
O	VAL159
b	LEU41

site_id	AF4
Number of Residues	11
Details	binding site for residue PLC P 401

Chain	Residue
A	3PE502
B	TRP207
P	GLU134
P	THR135
P	LYS136
P	GLN302
P	ALA303
P	ILE304
P	TRP305
P	TRP306
P	PRO307

site_id	AF5
Number of Residues	15
Details	binding site for residue NDP P 402

Chain	Residue
P	GLY60
P	PHE64
P	LEU65
P	ARG85
P	LEU109
P	LEU128
P	ILE129
P	GLY130
P	ARG131
P	PHE138
P	VAL166
P	ALA168
P	LYS183
P	MET205
P	HOH510

site_id	AF6
Number of Residues	7
Details	binding site for residue CDL P 403

Chain	Residue
A	TYR28
A	3PE502
P	ARG216
P	ARG219
P	SER220
P	LEU289
P	TYR297

site_id	AF7
Number of Residues	4
Details	binding site for residue ZN R 201

Chain	Residue
R	CYS97
R	HIS110
R	CYS125
R	CYS128

site_id	AF8
Number of Residues	10
Details	binding site for residue EHZ T 201

Chain	Residue
T	SER66
W	GLN22
W	LEU26
W	PHE32
W	GLU59
W	PHE60
W	HIS63
W	ARG64
W	VAL66
W	GLN72

site_id	AF9
Number of Residues	9
Details	binding site for residue EHZ U 201

Chain	Residue
U	SER89
n	PRO6
n	ASN11
n	LYS46
n	PHE47
n	ASN50
n	LEU59
n	THR62
n	THR66

site_id	AG1
Number of Residues	5
Details	binding site for residue LMT Y 4201

Chain	Residue
M	ILE209
Y	ALA145
Y	PHE163
Y	TRP164
Y	LMT4202

site_id	AG2
Number of Residues	6
Details	binding site for residue LMT Y 4202

Chain	Residue
M	PHE177
Y	LEU131
Y	TRP134
Y	THR135
Y	GLY136
Y	LMT4201

site_id	AG3
Number of Residues	4
Details	binding site for residue 3PE Y 4203

Chain	Residue
Y	ASP93
Y	GLY94
Y	TRP95
Y	TRP134

site_id	AG4
Number of Residues	4
Details	binding site for residue LMT Y 4204

Chain	Residue
Y	ARG89
Y	TRP95
Y	MET98
Y	TRP99

site_id	AG5
Number of Residues	7
Details	binding site for residue CDL Z 201

Chain	Residue
I	TYR88
Z	ARG26
Z	GLY27
Z	PHE28
Z	ARG29
Z	TYR33
Z	3PE202

site_id	AG6
Number of Residues	9
Details	binding site for residue 3PE Z 202

Chain	Residue
H	TRP295
I	LYS76
I	ALA81
Z	ARG26
Z	GLY27
Z	PHE28
Z	PRO30
Z	TYR33
Z	CDL201

site_id	AG7
Number of Residues	8
Details	binding site for residue 3PE Z 203

Chain	Residue
H	ILE326
X	TRP149
Z	PHE45
Z	TYR46
Z	GLN53
b	ALA35
b	LEU43
b	TYR52

site_id	AG8
Number of Residues	8
Details	binding site for residue CDL a 101

Chain	Residue
I	TYR88
I	PHE95
a	ALA2
a	ILE3
c	SER17
c	TRP21
c	LEU28
f	SER4

site_id	AG9
Number of Residues	11
Details	binding site for residue CDL b 401

Chain	Residue
N	SER8
N	THR11
N	MET15
O	LYS73
O	ARG76
O	VAL77
b	ASN5
b	PHE8
b	TRP9
b	TYR15
b	3PE402

site_id	AH1
Number of Residues	13
Details	binding site for residue 3PE b 402

Chain	Residue
A	ILE99
A	ASN107
A	ASN109
b	ASN5
b	TYR15
b	LEU16
b	SER19
b	ARG23
b	LEU26
b	ALA29
b	PHE30
b	CDL401
b	3PE403

site_id	AH2
Number of Residues	7
Details	binding site for residue 3PE b 403

Chain	Residue
I	LEU71
b	PHE13
b	ARG17
b	HIS21
b	PHE27
b	PHE28
b	3PE402

site_id	AH3
Number of Residues	6
Details	binding site for residue 3PE d 4601

Chain	Residue
M	ASN15
N	TYR359
d	PHE19
d	LYS23
d	ALA29
g	ASN113

site_id	AH4
Number of Residues	8
Details	binding site for residue PLC d 4602

Chain	Residue
N	SER437
N	TYR441
O	TRP59
O	LEU60
d	LYS18
d	TYR32
d	GLY35
d	ALA42

site_id	AH5
Number of Residues	4
Details	binding site for residue 3PE d 4603

Chain	Residue
d	GLY12
d	PHE19
d	ALA29
g	ASN113

Functional Information from PROSITE/UniProt

site_id	PS00542
Number of Residues	22
Details	COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREayDMYgvffegHpdlRrIM

Chain	Residue	Details
C	GLU179-MET200

site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK

Chain	Residue	Details
D	LEU119-LYS130

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaICP

Chain	Residue	Details
I	CYS130-PRO141
I	CYS169-PRO180

site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PryCYhdklaiaGnCRmC

Chain	Residue	Details
G	PRO66-CYS83

site_id	PS00642
Number of Residues	13
Details	COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPvCDqGGeCdLQ

Chain	Residue	Details
G	CYS133-GLN145

site_id	PS00643
Number of Residues	11
Details	COMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIhCtRCVrF

Chain	Residue	Details
G	ARG182-PHE192

site_id	PS01150
Number of Residues	17
Details	COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDVYvPgCPP

Chain	Residue	Details
B	GLY166-PRO182

site_id	PS01099
Number of Residues	19
Details	COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DnlFTlseveCLGaCvnAP

Chain	Residue	Details
E	ASP158-PRO176

site_id	PS00644
Number of Residues	16
Details	COMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GMGAYVCGEETSLIES

Chain	Residue	Details
F	GLY202-SER217

site_id	PS00645
Number of Residues	12
Details	COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG

Chain	Residue	Details
F	GLU379-GLY390

site_id	PS00133
Number of Residues	11
Details	CARBOXYPEPT_ZN_2 Zinc carboxypeptidases, zinc-binding region 2 signature. HSIAGLFiFPW

Chain	Residue	Details
O	HIS145-TRP155

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQaFaDAVKLLlKE

Chain	Residue	Details
H	GLY46-GLU61

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLTESEseLVa.G

Chain	Residue	Details
H	PRO201-GLY214

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDVVEVVMAI

Chain	Residue	Details
U	ASP84-ILE99
T	ASP61-ILE76

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	260
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
N	LEU27-LEU47
N	SER317-ILE337
N	VAL361-PHE381
N	PHE397-LEU417
N	TYR441-ILE461
L	ILE456-LEU476
L	ILE516-PHE536
L	LEU629-ILE649
N	LEU59-ILE79
N	ILE104-ILE124
N	THR125-ASN145
N	ALA153-ASN173
N	LEU197-LEU217
N	ILE230-LEU250
N	SER257-LEU277
N	LEU284-ASN304

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)