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6YIE

Structure of a Borealin-INCENP-Survivin complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0000228cellular_componentnuclear chromosome
A0000278biological_processmitotic cell cycle
A0000281biological_processmitotic cytokinesis
A0000775cellular_componentchromosome, centromeric region
A0000776cellular_componentkinetochore
A0004869molecular_functioncysteine-type endopeptidase inhibitor activity
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005694cellular_componentchromosome
A0005737cellular_componentcytoplasm
A0005819cellular_componentspindle
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0005874cellular_componentmicrotubule
A0006468biological_processprotein phosphorylation
A0006915biological_processapoptotic process
A0007059biological_processchromosome segregation
A0007605biological_processsensory perception of sound
A0008017molecular_functionmicrotubule binding
A0008284biological_processpositive regulation of cell population proliferation
A0015630cellular_componentmicrotubule cytoskeleton
A0019899molecular_functionenzyme binding
A0030496cellular_componentmidbody
A0031267molecular_functionsmall GTPase binding
A0031503biological_processprotein-containing complex localization
A0032133cellular_componentchromosome passenger complex
A0042802molecular_functionidentical protein binding
A0042981biological_processregulation of apoptotic process
A0043066biological_processnegative regulation of apoptotic process
A0045892biological_processnegative regulation of DNA-templated transcription
A0046872molecular_functionmetal ion binding
A0051087molecular_functionprotein-folding chaperone binding
A0051256biological_processmitotic spindle midzone assembly
A0051301biological_processcell division
A0090267biological_processpositive regulation of mitotic cell cycle spindle assembly checkpoint
A0090307biological_processmitotic spindle assembly
A1901970biological_processpositive regulation of mitotic sister chromatid separation
A1902425biological_processpositive regulation of attachment of mitotic spindle microtubules to kinetochore
A1903490biological_processpositive regulation of mitotic cytokinesis
A1990713cellular_componentsurvivin complex
D0000228cellular_componentnuclear chromosome
D0000278biological_processmitotic cell cycle
D0000281biological_processmitotic cytokinesis
D0000775cellular_componentchromosome, centromeric region
D0000776cellular_componentkinetochore
D0004869molecular_functioncysteine-type endopeptidase inhibitor activity
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005654cellular_componentnucleoplasm
D0005694cellular_componentchromosome
D0005737cellular_componentcytoplasm
D0005819cellular_componentspindle
D0005829cellular_componentcytosol
D0005856cellular_componentcytoskeleton
D0005874cellular_componentmicrotubule
D0006468biological_processprotein phosphorylation
D0006915biological_processapoptotic process
D0007059biological_processchromosome segregation
D0007605biological_processsensory perception of sound
D0008017molecular_functionmicrotubule binding
D0008284biological_processpositive regulation of cell population proliferation
D0015630cellular_componentmicrotubule cytoskeleton
D0019899molecular_functionenzyme binding
D0030496cellular_componentmidbody
D0031267molecular_functionsmall GTPase binding
D0031503biological_processprotein-containing complex localization
D0032133cellular_componentchromosome passenger complex
D0042802molecular_functionidentical protein binding
D0042981biological_processregulation of apoptotic process
D0043066biological_processnegative regulation of apoptotic process
D0045892biological_processnegative regulation of DNA-templated transcription
D0046872molecular_functionmetal ion binding
D0051087molecular_functionprotein-folding chaperone binding
D0051256biological_processmitotic spindle midzone assembly
D0051301biological_processcell division
D0090267biological_processpositive regulation of mitotic cell cycle spindle assembly checkpoint
D0090307biological_processmitotic spindle assembly
D1901970biological_processpositive regulation of mitotic sister chromatid separation
D1902425biological_processpositive regulation of attachment of mitotic spindle microtubules to kinetochore
D1903490biological_processpositive regulation of mitotic cytokinesis
D1990713cellular_componentsurvivin complex
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue ZN A 201
ChainResidue
ACYS57
ACYS60
AHIS77
ACYS84

site_idAC2
Number of Residues4
Detailsbinding site for residue ZN D 201
ChainResidue
DCYS57
DCYS60
DHIS77
DCYS84

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsMOD_RES: Phosphothreonine; by TTK => ECO:0000269|PubMed:19530738
ChainResidueDetails
BTHR88
BTHR94
ETHR88
ETHR94
DCYS57
DCYS60
DHIS77
DCYS84

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163
ChainResidueDetails
BTHR106
ETHR106

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphoserine; by AURKC => ECO:0000269|PubMed:27332895
ChainResidueDetails
ASER20
DSER20

site_idSWS_FT_FI4
Number of Residues14
DetailsMOD_RES: N6-acetyllysine => ECO:0000269|PubMed:20826784
ChainResidueDetails
ALYS23
ALYS90
ALYS110
ALYS112
ALYS115
ALYS121
ALYS129
DLYS23
DLYS90
DLYS110
DLYS112
DLYS115
DLYS121
DLYS129

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: Phosphothreonine; by CDK1 and CDK15 => ECO:0000269|PubMed:11069302, ECO:0000269|PubMed:24866247, ECO:0007744|PubMed:18691976
ChainResidueDetails
ATHR34
DTHR34

site_idSWS_FT_FI6
Number of Residues2
DetailsMOD_RES: Phosphothreonine; by CK2; in vitro => ECO:0000269|PubMed:21252625
ChainResidueDetails
ATHR48
DTHR48

site_idSWS_FT_FI7
Number of Residues2
DetailsMOD_RES: Phosphothreonine; by AURKB => ECO:0000269|PubMed:14610074
ChainResidueDetails
ATHR117
DTHR117

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PDB entries from 2024-06-12

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