6YGD
Crystal structure of the NatC complex bound to Gag peptide and CoA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004596 | molecular_function | protein-N-terminal amino-acid acetyltransferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006474 | biological_process | N-terminal protein amino acid acetylation |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0017196 | biological_process | N-terminal peptidyl-methionine acetylation |
| A | 0031417 | cellular_component | NatC complex |
| A | 0032880 | biological_process | regulation of protein localization |
| A | 0120518 | molecular_function | protein N-terminal-methionine acetyltransferase activity |
| B | 0004596 | molecular_function | protein-N-terminal amino-acid acetyltransferase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006474 | biological_process | N-terminal protein amino acid acetylation |
| B | 0016236 | biological_process | macroautophagy |
| B | 0017196 | biological_process | N-terminal peptidyl-methionine acetylation |
| B | 0031417 | cellular_component | NatC complex |
| C | 0003723 | molecular_function | RNA binding |
| C | 0031417 | cellular_component | NatC complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue COA A 201 |
| Chain | Residue |
| A | LEU27 |
| A | LYS97 |
| A | ASN123 |
| A | ALA125 |
| A | ALA126 |
| A | ASN128 |
| A | LEU129 |
| A | TYR130 |
| D | MET1 |
| A | LEU84 |
| A | VAL86 |
| A | ARG91 |
| A | GLY92 |
| A | HIS93 |
| A | GLY94 |
| A | ILE95 |
| A | ALA96 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue IOD B 801 |
| Chain | Residue |
| A | ARG140 |
| B | ARG408 |
| B | GLN409 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue IOD B 804 |
| Chain | Residue |
| B | THR107 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue IOD B 805 |
| Chain | Residue |
| B | LYS681 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue IOD B 807 |
| Chain | Residue |
| B | THR628 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 811 |
| Chain | Residue |
| B | TRP396 |
| B | SER444 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 814 |
| Chain | Residue |
| B | GLU542 |
| B | THR546 |
| B | TYR672 |
| B | LEU676 |
| B | PHE720 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 815 |
| Chain | Residue |
| A | GLU2 |
| A | LYS54 |
| B | ASN655 |
| B | VAL657 |
| B | HOH913 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | binding site for residue EDO B 816 |
| Chain | Residue |
| B | ASN692 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 817 |
| Chain | Residue |
| B | ARG93 |
| B | PRO266 |
| B | PRO267 |
| B | GLY269 |
| B | ALA270 |
| B | PHE271 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 818 |
| Chain | Residue |
| B | ASN544 |
| B | SER548 |
| B | GLU634 |
| B | SER641 |
| site_id | AD3 |
| Number of Residues | 1 |
| Details | binding site for residue IOD C 101 |
| Chain | Residue |
| B | GLN282 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue IOD C 102 |
| Chain | Residue |
| C | LYS5 |
| C | LEU6 |
| C | SER7 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 156 |
| Details | Domain: {"description":"N-acetyltransferase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00532","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylmethionine; by host N-acetyltransferase MAK3","evidences":[{"source":"PubMed","id":"1400344","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
