6YGC
Crystal structure of the NatC complex bound to Arl3 peptide and CoA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004596 | molecular_function | protein-N-terminal amino-acid acetyltransferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0017196 | biological_process | N-terminal peptidyl-methionine acetylation |
| A | 0031417 | cellular_component | NatC complex |
| A | 0032880 | biological_process | regulation of protein localization |
| A | 0120518 | molecular_function | protein N-terminal-methionine acetyltransferase activity |
| B | 0004596 | molecular_function | protein-N-terminal amino-acid acetyltransferase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0016236 | biological_process | macroautophagy |
| B | 0017196 | biological_process | N-terminal peptidyl-methionine acetylation |
| B | 0031417 | cellular_component | NatC complex |
| C | 0003723 | molecular_function | RNA binding |
| C | 0031417 | cellular_component | NatC complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue COA A 201 |
| Chain | Residue |
| A | LEU84 |
| A | ALA126 |
| A | ASN128 |
| A | LEU129 |
| A | TYR130 |
| B | ARG731 |
| D | MET1 |
| A | ARG91 |
| A | GLY92 |
| A | HIS93 |
| A | GLY94 |
| A | ALA96 |
| A | LYS97 |
| A | ASN123 |
| A | ALA125 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 203 |
| Chain | Residue |
| A | MET138 |
| A | LYS153 |
| A | ILE155 |
| B | LYS588 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue IOD B 802 |
| Chain | Residue |
| B | PHE461 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue IOD B 803 |
| Chain | Residue |
| B | GLU119 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue IOD B 804 |
| Chain | Residue |
| B | THR107 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue IOD B 805 |
| Chain | Residue |
| B | GLN282 |
| C | GLY54 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 808 |
| Chain | Residue |
| B | ARG93 |
| B | PRO266 |
| B | PRO267 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 810 |
| Chain | Residue |
| B | ASN383 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 811 |
| Chain | Residue |
| B | THR546 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 812 |
| Chain | Residue |
| B | GLN528 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 813 |
| Chain | Residue |
| B | LYS325 |
| B | LYS329 |
| B | GLU447 |
| B | GLU542 |
| B | TYR672 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 814 |
| Chain | Residue |
| B | ILE545 |
| B | SER548 |
| B | GLU634 |
| B | ASN637 |
| B | SER641 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 815 |
| Chain | Residue |
| B | GLN422 |
| B | CYS434 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 156 |
| Details | Domain: {"description":"N-acetyltransferase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00532","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"15077113","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15077114","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
