Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | ARG225 |
| A | VAL413 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | binding site for residue OQ8 A 502 |
| Chain | Residue |
| A | GLY216 |
| A | CYS218 |
| A | LYS221 |
| A | VAL255 |
| A | ILE256 |
| A | HIS257 |
| A | ARG258 |
| A | SER263 |
| A | LEU275 |
| A | CYS276 |
| A | ASP277 |
| A | PHE278 |
| A | HOH677 |
| A | LYS165 |
| A | VAL186 |
| A | ILE195 |
| A | VAL196 |
| A | MET212 |
| A | GLU213 |
| A | MET215 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 501 |
| Chain | Residue |
| B | GLU232 |
| B | ARG398 |
| B | TYR399 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 502 |
| Chain | Residue |
| B | GLY364 |
| B | HOH612 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| B | ARG225 |
| B | VAL413 |
| B | MET414 |
| B | LYS416 |
| site_id | AC6 |
| Number of Residues | 23 |
| Details | binding site for Di-peptide OQ8 B 504 and CYS B 218 |
| Chain | Residue |
| B | ASP182 |
| B | VAL186 |
| B | VAL196 |
| B | MET212 |
| B | GLU213 |
| B | MET215 |
| B | GLY216 |
| B | THR217 |
| B | ALA219 |
| B | GLU220 |
| B | LYS221 |
| B | LEU222 |
| B | VAL255 |
| B | ILE256 |
| B | HIS257 |
| B | SER263 |
| B | ILE265 |
| B | LEU266 |
| B | LEU275 |
| B | CYS276 |
| B | ASP277 |
| B | PHE278 |
| B | HOH650 |
Functional Information from PROSITE/UniProt
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ViHrDVKpsNILL |
| Chain | Residue | Details |
| A | VAL255-LEU267 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | VAL243 | |
| B | VAL243 | |
| Chain | Residue | Details |
| A | GLY126 | |
| A | GLN149 | |
| B | GLY126 | |
| B | GLN149 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by MAP3K => ECO:0000250 |
| Chain | Residue | Details |
| A | GLY271 | |
| B | GLY271 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by MAP3K => ECO:0000250 |
| Chain | Residue | Details |
| A | LEU275 | |
| B | LEU275 | |
| Chain | Residue | Details |
| A | LYS411 | |
| B | LYS411 | |
