Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6YEH

Arabidopsis thaliana glutamate dehydrogenase isoform 1 in apo form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004352	molecular_function	glutamate dehydrogenase (NAD+) activity
A	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
A	0004354	molecular_function	glutamate dehydrogenase (NADP+) activity
A	0005507	molecular_function	copper ion binding
A	0005524	molecular_function	ATP binding
A	0005739	cellular_component	mitochondrion
A	0006520	biological_process	amino acid metabolic process
A	0006807	biological_process	obsolete nitrogen compound metabolic process
A	0008270	molecular_function	zinc ion binding
A	0009536	cellular_component	plastid
A	0009646	biological_process	response to absence of light
A	0016491	molecular_function	oxidoreductase activity
A	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
A	0050897	molecular_function	cobalt ion binding
B	0004352	molecular_function	glutamate dehydrogenase (NAD+) activity
B	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
B	0004354	molecular_function	glutamate dehydrogenase (NADP+) activity
B	0005507	molecular_function	copper ion binding
B	0005524	molecular_function	ATP binding
B	0005739	cellular_component	mitochondrion
B	0006520	biological_process	amino acid metabolic process
B	0006807	biological_process	obsolete nitrogen compound metabolic process
B	0008270	molecular_function	zinc ion binding
B	0009536	cellular_component	plastid
B	0009646	biological_process	response to absence of light
B	0016491	molecular_function	oxidoreductase activity
B	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
B	0050897	molecular_function	cobalt ion binding
C	0004352	molecular_function	glutamate dehydrogenase (NAD+) activity
C	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
C	0004354	molecular_function	glutamate dehydrogenase (NADP+) activity
C	0005507	molecular_function	copper ion binding
C	0005524	molecular_function	ATP binding
C	0005739	cellular_component	mitochondrion
C	0006520	biological_process	amino acid metabolic process
C	0006807	biological_process	obsolete nitrogen compound metabolic process
C	0008270	molecular_function	zinc ion binding
C	0009536	cellular_component	plastid
C	0009646	biological_process	response to absence of light
C	0016491	molecular_function	oxidoreductase activity
C	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
C	0050897	molecular_function	cobalt ion binding
D	0004352	molecular_function	glutamate dehydrogenase (NAD+) activity
D	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
D	0004354	molecular_function	glutamate dehydrogenase (NADP+) activity
D	0005507	molecular_function	copper ion binding
D	0005524	molecular_function	ATP binding
D	0005739	cellular_component	mitochondrion
D	0006520	biological_process	amino acid metabolic process
D	0006807	biological_process	obsolete nitrogen compound metabolic process
D	0008270	molecular_function	zinc ion binding
D	0009536	cellular_component	plastid
D	0009646	biological_process	response to absence of light
D	0016491	molecular_function	oxidoreductase activity
D	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
D	0050897	molecular_function	cobalt ion binding
E	0004352	molecular_function	glutamate dehydrogenase (NAD+) activity
E	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
E	0004354	molecular_function	glutamate dehydrogenase (NADP+) activity
E	0005507	molecular_function	copper ion binding
E	0005524	molecular_function	ATP binding
E	0005739	cellular_component	mitochondrion
E	0006520	biological_process	amino acid metabolic process
E	0006807	biological_process	obsolete nitrogen compound metabolic process
E	0008270	molecular_function	zinc ion binding
E	0009536	cellular_component	plastid
E	0009646	biological_process	response to absence of light
E	0016491	molecular_function	oxidoreductase activity
E	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
E	0050897	molecular_function	cobalt ion binding
F	0004352	molecular_function	glutamate dehydrogenase (NAD+) activity
F	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
F	0004354	molecular_function	glutamate dehydrogenase (NADP+) activity
F	0005507	molecular_function	copper ion binding
F	0005524	molecular_function	ATP binding
F	0005739	cellular_component	mitochondrion
F	0006520	biological_process	amino acid metabolic process
F	0006807	biological_process	obsolete nitrogen compound metabolic process
F	0008270	molecular_function	zinc ion binding
F	0009536	cellular_component	plastid
F	0009646	biological_process	response to absence of light
F	0016491	molecular_function	oxidoreductase activity
F	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
F	0050897	molecular_function	cobalt ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MPD A 501

Chain	Residue
A	TYR71
A	LEU117
A	GLY144
A	THR149
A	TRP152

site_id	AC2
Number of Residues	4
Details	binding site for residue MPD A 502

Chain	Residue
A	GLU199
A	HIS200
A	CYS386
A	LEU388

site_id	AC3
Number of Residues	7
Details	binding site for residue MPD A 503

Chain	Residue
A	TYR163
A	PRO165
A	ASN351
A	GLY354
A	MET356
E	PRO97
E	TRP348

site_id	AC4
Number of Residues	4
Details	binding site for residue MPD A 504

Chain	Residue
A	GLU34
A	LYS36
A	PHE54
A	PRO77

site_id	AC5
Number of Residues	3
Details	binding site for residue K A 505

Chain	Residue
A	SER27
A	ILE30
B	GLU38

site_id	AC6
Number of Residues	4
Details	binding site for residue K A 506

Chain	Residue
A	GLU38
B	SER27
B	ILE30
B	ASP59

site_id	AC7
Number of Residues	4
Details	binding site for residue MPD B 501

Chain	Residue
B	GLU34
B	LYS36
B	VAL56
B	PRO77

site_id	AC8
Number of Residues	3
Details	binding site for residue K C 501

Chain	Residue
C	SER27
C	ILE30
D	GLU38

site_id	AC9
Number of Residues	3
Details	binding site for residue MPD C 502

Chain	Residue
C	GLU34
C	VAL75
C	PRO77

site_id	AD1
Number of Residues	3
Details	binding site for residue MPD C 503

Chain	Residue
C	LEU117
C	GLY144
C	THR149

site_id	AD2
Number of Residues	3
Details	binding site for residue K D 501

Chain	Residue
C	GLU38
D	SER27
D	ILE30

site_id	AD3
Number of Residues	4
Details	binding site for residue MPD D 502

Chain	Residue
D	LEU86
D	MET87
D	LYS90
D	ASN312

site_id	AD4
Number of Residues	6
Details	binding site for residue MPD E 501

Chain	Residue
A	GLU358
C	ASN244
C	LYS245
E	ASP364
E	GLU365
E	THR368

site_id	AD5
Number of Residues	3
Details	binding site for residue K E 502

Chain	Residue
E	SER27
E	ILE30
F	GLU38

site_id	AD6
Number of Residues	5
Details	binding site for residue MPD E 503

Chain	Residue
C	PRO64
C	PRO97
E	PRO165
E	ASN351
E	MET356

site_id	AD7
Number of Residues	5
Details	binding site for residue MPD E 504

Chain	Residue
E	GLU34
E	LYS36
E	PHE54
E	VAL56
E	PRO77

site_id	AD8
Number of Residues	3
Details	binding site for residue K E 505

Chain	Residue
E	GLU38
F	SER27
F	ILE30

Functional Information from PROSITE/UniProt

site_id	PS00074
Number of Residues	14
Details	GLFV_DEHYDROGENASE Glu / Leu / Phe / Val dehydrogenases active site. IpyGGAKgGigcDP

Chain	Residue	Details
A	ILE96-PRO109

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: ACT_SITE => ECO:0000255\|PROSITE-ProRule:PRU10011

Chain	Residue	Details
A	LYS102
B	LYS102
C	LYS102
D	LYS102
E	LYS102
F	LYS102

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)