Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0008236 | molecular_function | serine-type peptidase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | binding site for residue CA A 601 |
Chain | Residue |
A | ASP174 |
A | ASP179 |
A | ASP181 |
A | HOH865 |
A | HOH891 |
A | HOH1064 |
site_id | AC2 |
Number of Residues | 6 |
Details | binding site for residue CA A 602 |
Chain | Residue |
A | ASN208 |
A | VAL210 |
A | GLY212 |
A | ASP115 |
A | ASP162 |
A | VAL205 |
site_id | AC3 |
Number of Residues | 6 |
Details | binding site for residue CA A 603 |
Chain | Residue |
A | ASP258 |
A | ASP301 |
A | GLU331 |
A | HOH814 |
A | HOH819 |
A | HOH936 |
site_id | AC4 |
Number of Residues | 4 |
Details | binding site for residue NA A 604 |
Chain | Residue |
A | THR309 |
A | SER311 |
A | THR314 |
A | HOH795 |
site_id | AC5 |
Number of Residues | 6 |
Details | binding site for residue NA A 605 |
Chain | Residue |
A | SER279 |
A | GLY284 |
A | HOH762 |
A | HOH809 |
A | HOH1070 |
A | HOH1094 |
site_id | AC6 |
Number of Residues | 4 |
Details | binding site for residue NA A 606 |
Chain | Residue |
A | SER544 |
A | SER544 |
A | HOH871 |
A | HOH871 |
site_id | AC7 |
Number of Residues | 3 |
Details | binding site for residue CL A 607 |
Chain | Residue |
A | ARG276 |
A | LYS449 |
A | TYR571 |
site_id | AC8 |
Number of Residues | 4 |
Details | binding site for residue PO4 A 608 |
Chain | Residue |
A | PHE118 |
A | PRO119 |
A | GLN121 |
A | SER125 |
site_id | AC9 |
Number of Residues | 5 |
Details | binding site for residue PO4 A 609 |
Chain | Residue |
A | VAL326 |
A | GLN346 |
A | ASN347 |
A | ALA408 |
A | ASN409 |
site_id | AD1 |
Number of Residues | 5 |
Details | binding site for residue DMS A 610 |
Chain | Residue |
A | VAL263 |
A | GLY527 |
A | PHE528 |
A | ASN529 |
A | HOH791 |
site_id | AD2 |
Number of Residues | 12 |
Details | binding site for residues BVK A 611 and ON8 A 612 |
Chain | Residue |
A | VAL231 |
A | GLU236 |
A | GLY255 |
A | PRO256 |
A | GLU257 |
A | ASP264 |
A | TYR308 |
611 | TBG2003 |
A | HOH749 |
A | HOH969 |
A | HOH998 |
A | HOH1048 |
site_id | AD3 |
Number of Residues | 12 |
Details | binding site for residues BVK A 611 and ON8 A 612 |
Chain | Residue |
A | VAL231 |
A | GLU236 |
A | GLY255 |
A | PRO256 |
A | GLU257 |
A | ASP264 |
A | TYR308 |
611 | TBG2003 |
A | HOH749 |
A | HOH969 |
A | HOH998 |
A | HOH1048 |
site_id | AD4 |
Number of Residues | 12 |
Details | binding site for residues ON8 A 612 and TBG A 613 |
Chain | Residue |
A | VAL231 |
A | GLU236 |
A | TRP254 |
A | GLY255 |
A | PRO256 |
A | ASP264 |
A | TYR308 |
611 | BVK2001 |
611 | LYS2004 |
611 | 00S2005 |
A | HOH998 |
A | HOH1048 |
site_id | AD5 |
Number of Residues | 10 |
Details | binding site for Di-peptide TBG A 613 and LYS A 614 |
Chain | Residue |
A | ASP154 |
A | ASP191 |
A | ASN192 |
A | LEU227 |
A | TRP254 |
A | GLY255 |
611 | GGB2002 |
611 | 00S2005 |
A | HOH770 |
A | HOH890 |
site_id | AD6 |
Number of Residues | 18 |
Details | binding site for Di-peptide LYS A 614 and 00S A 615 |
Chain | Residue |
A | SER253 |
A | TRP254 |
A | GLY255 |
A | PRO256 |
A | ASP258 |
A | ALA292 |
A | ASN295 |
A | ASP306 |
A | THR309 |
A | THR367 |
A | SER368 |
611 | TBG2003 |
A | HOH770 |
A | HOH890 |
A | ASP154 |
A | ASP191 |
A | ASN192 |
A | LEU227 |
Functional Information from PROSITE/UniProt
site_id | PS00136 |
Number of Residues | 12 |
Details | SUBTILASE_ASP Serine proteases, subtilase family, aspartic acid active site. VSILDDGIeknH |
Chain | Residue | Details |
A | VAL149-HIS160 | |
site_id | PS00137 |
Number of Residues | 11 |
Details | SUBTILASE_HIS Serine proteases, subtilase family, histidine active site. HGTrCAGeVAA |
Chain | Residue | Details |
A | HIS194-ALA204 | |
site_id | PS00138 |
Number of Residues | 11 |
Details | SUBTILASE_SER Serine proteases, subtilase family, serine active site. GTSaSaPlAAG |
Chain | Residue | Details |
A | GLY366-GLY376 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP153 | |
A | HIS194 | |
A | SER368 | |
Chain | Residue | Details |
A | ASP115 | |
A | ASP258 | |
A | ASP301 | |
A | GLU331 | |
A | ASP162 | |
A | ASP174 | |
A | ASP179 | |
A | ASP181 | |
A | VAL205 | |
A | ASN208 | |
A | VAL210 | |
A | GLY212 | |
Chain | Residue | Details |
A | ASP154 | |
A | ASP191 | |
A | GLU236 | |
A | SER253 | |
A | ASP264 | |
A | ALA292 | |
A | ASP306 | |
A | TYR308 | |
A | SER368 | |
site_id | SWS_FT_FI4 |
Number of Residues | 3 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
A | ASN387 | |
A | ASN440 | |
A | ASN553 | |