6YCA
Crystal structure of Eis1 from Mycobacterium abscessus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0008080 | molecular_function | N-acetyltransferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| A | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| A | 0044161 | cellular_component | host cell cytoplasmic vesicle |
| B | 0005576 | cellular_component | extracellular region |
| B | 0008080 | molecular_function | N-acetyltransferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| B | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| B | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| B | 0044161 | cellular_component | host cell cytoplasmic vesicle |
| C | 0005576 | cellular_component | extracellular region |
| C | 0008080 | molecular_function | N-acetyltransferase activity |
| C | 0016746 | molecular_function | acyltransferase activity |
| C | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| C | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| C | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| C | 0044161 | cellular_component | host cell cytoplasmic vesicle |
| D | 0005576 | cellular_component | extracellular region |
| D | 0008080 | molecular_function | N-acetyltransferase activity |
| D | 0016746 | molecular_function | acyltransferase activity |
| D | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| D | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| D | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| D | 0044161 | cellular_component | host cell cytoplasmic vesicle |
| E | 0005576 | cellular_component | extracellular region |
| E | 0008080 | molecular_function | N-acetyltransferase activity |
| E | 0016746 | molecular_function | acyltransferase activity |
| E | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| E | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| E | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| E | 0044161 | cellular_component | host cell cytoplasmic vesicle |
| F | 0005576 | cellular_component | extracellular region |
| F | 0008080 | molecular_function | N-acetyltransferase activity |
| F | 0016746 | molecular_function | acyltransferase activity |
| F | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| F | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| F | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| F | 0044161 | cellular_component | host cell cytoplasmic vesicle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue ACO A 501 |
| Chain | Residue |
| A | ALA45 |
| A | THR115 |
| A | SER138 |
| A | GLU139 |
| A | VAL141 |
| A | ILE142 |
| A | TYR143 |
| A | ARG145 |
| F | ASP273 |
| A | ILE102 |
| A | VAL104 |
| A | THR109 |
| A | ARG110 |
| A | ARG111 |
| A | GLY112 |
| A | ILE113 |
| A | LEU114 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 502 |
| Chain | Residue |
| A | ARG27 |
| A | PHE28 |
| A | ARG120 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 503 |
| Chain | Residue |
| A | LEU167 |
| A | ARG168 |
| D | ARG144 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 504 |
| Chain | Residue |
| A | THR405 |
| A | GLY406 |
| A | THR407 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 505 |
| Chain | Residue |
| A | ARG144 |
| A | ARG145 |
| D | LEU167 |
| D | ARG168 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 506 |
| Chain | Residue |
| A | ARG163 |
| A | ARG297 |
| D | ARG305 |
| E | SER244 |
| site_id | AC7 |
| Number of Residues | 19 |
| Details | binding site for residue ACO B 501 |
| Chain | Residue |
| A | ASP273 |
| B | ALA45 |
| B | MET46 |
| B | ILE102 |
| B | VAL104 |
| B | THR109 |
| B | ARG110 |
| B | ARG111 |
| B | GLY112 |
| B | ILE113 |
| B | LEU114 |
| B | THR115 |
| B | LEU135 |
| B | ARG136 |
| B | SER138 |
| B | GLU139 |
| B | VAL141 |
| B | TYR143 |
| B | ARG145 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 502 |
| Chain | Residue |
| B | ARG144 |
| B | ARG145 |
| E | LEU167 |
| E | ARG168 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 503 |
| Chain | Residue |
| B | GLY406 |
| B | THR407 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 504 |
| Chain | Residue |
| B | ARG27 |
| B | PHE28 |
| B | ARG120 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 505 |
| Chain | Residue |
| B | THR356 |
| B | GLN357 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 506 |
| Chain | Residue |
| A | SER244 |
| A | SER245 |
| B | ARG305 |
| E | ARG163 |
| E | ARG297 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 507 |
| Chain | Residue |
| B | ARG163 |
| B | ARG297 |
| C | ARG247 |
| E | ARG305 |
| site_id | AD5 |
| Number of Residues | 21 |
| Details | binding site for residue ACO C 501 |
| Chain | Residue |
| C | ALA45 |
| C | MET46 |
| C | ILE102 |
| C | GLY103 |
| C | VAL104 |
| C | THR109 |
| C | ARG110 |
| C | ARG111 |
| C | GLY112 |
| C | ILE113 |
| C | LEU114 |
| C | THR115 |
| C | LEU135 |
| C | ARG136 |
| C | SER138 |
| C | GLU139 |
| C | VAL141 |
| C | TYR143 |
| C | ARG145 |
| D | ASP273 |
| D | LEU274 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 502 |
| Chain | Residue |
| C | GLY406 |
| C | THR407 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 503 |
| Chain | Residue |
| F | ARG168 |
| C | ARG144 |
| C | ARG145 |
| F | LEU167 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 504 |
| Chain | Residue |
| C | ARG27 |
| C | PHE28 |
| C | ARG120 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 505 |
| Chain | Residue |
| C | ARG354 |
| C | THR356 |
| C | GLN357 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 506 |
| Chain | Residue |
| C | LEU167 |
| C | ARG168 |
| F | ARG144 |
| site_id | AE2 |
| Number of Residues | 20 |
| Details | binding site for residue ACO D 501 |
| Chain | Residue |
| D | ALA45 |
| D | MET46 |
| D | ILE102 |
| D | GLY103 |
| D | VAL104 |
| D | THR109 |
| D | ARG110 |
| D | ARG111 |
| D | GLY112 |
| D | LEU114 |
| D | THR115 |
| D | ARG136 |
| D | SER138 |
| D | GLU139 |
| D | VAL141 |
| D | ILE142 |
| D | TYR143 |
| D | ARG145 |
| E | ASP273 |
| E | LEU274 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 502 |
| Chain | Residue |
| A | ARG397 |
| D | GLY406 |
| D | THR407 |
| site_id | AE4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 503 |
| Chain | Residue |
| D | ARG27 |
| D | PHE28 |
| D | ARG120 |
| site_id | AE5 |
| Number of Residues | 20 |
| Details | binding site for residue ACO E 501 |
| Chain | Residue |
| C | ASP273 |
| C | LEU274 |
| E | ALA45 |
| E | MET46 |
| E | ILE102 |
| E | GLY103 |
| E | VAL104 |
| E | THR109 |
| E | ARG110 |
| E | ARG111 |
| E | GLY112 |
| E | ILE113 |
| E | LEU114 |
| E | THR115 |
| E | ARG136 |
| E | SER138 |
| E | GLU139 |
| E | VAL141 |
| E | TYR143 |
| E | ARG145 |
| site_id | AE6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 E 502 |
| Chain | Residue |
| B | THR380 |
| E | GLY406 |
| E | THR407 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 E 503 |
| Chain | Residue |
| E | ARG27 |
| E | PHE28 |
| E | ARG120 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 E 504 |
| Chain | Residue |
| B | LEU167 |
| B | ARG168 |
| E | ARG144 |
| E | ARG145 |
| site_id | AE9 |
| Number of Residues | 21 |
| Details | binding site for residue ACO F 501 |
| Chain | Residue |
| B | ASP273 |
| B | LEU274 |
| F | ALA45 |
| F | MET46 |
| F | HIS101 |
| F | ILE102 |
| F | VAL104 |
| F | THR109 |
| F | ARG110 |
| F | ARG111 |
| F | GLY112 |
| F | LEU114 |
| F | THR115 |
| F | LEU135 |
| F | ARG136 |
| F | SER138 |
| F | GLU139 |
| F | VAL141 |
| F | ILE142 |
| F | TYR143 |
| F | ARG145 |
| site_id | AF1 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 F 502 |
| Chain | Residue |
| F | GLY406 |
| F | THR407 |
| site_id | AF2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 F 503 |
| Chain | Residue |
| F | ARG27 |
| F | PHE28 |
| F | ARG120 |
