6YC0

Crystal structure of the steady-state-SMX activated state of the light-driven sodium pump KR2 in the pentameric form at room temperature, pH 8.0

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016020	cellular_component	membrane
B	0016020	cellular_component	membrane
C	0016020	cellular_component	membrane
D	0016020	cellular_component	membrane
E	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	binding site for residue OLC A 301

Chain	Residue
A	MET148

---

site_id	AC2
Number of Residues	3
Details	binding site for residue OLC A 302

Chain	Residue
A	TYR45
A	OLC316
B	ILE115

---

site_id	AC3
Number of Residues	4
Details	binding site for residue OLC A 304

Chain	Residue
A	ASN163
A	THR165
A	VAL169
A	OLC305

---

site_id	AC4
Number of Residues	5
Details	binding site for residue OLC A 305

Chain	Residue
A	ASN163
A	ALA166
A	TRP170
A	OLC304
A	TYR159

---

site_id	AC5
Number of Residues	1
Details	binding site for residue LFA A 310

Chain	Residue
A	GLY171

---

site_id	AC6
Number of Residues	5
Details	binding site for residue NA A 312

Chain	Residue
A	TYR25
A	THR83
A	PHE86
B	ASP102
B	HOH446

---

site_id	AC7
Number of Residues	3
Details	binding site for residue OLC A 313

Chain	Residue
A	ILE115
A	OLC314
E	TYR45

---

site_id	AC8
Number of Residues	5
Details	binding site for residue OLC A 314

Chain	Residue
A	PHE122
A	ARG139
A	TRP143
A	OLC313
E	ASN264

---

site_id	AC9
Number of Residues	12
Details	binding site for residue RET A 315

Chain	Residue
A	TRP113
A	ASP116
A	LEU120
A	MET149
A	GLY171
A	SER174
A	PHE178
A	TRP215
A	TYR218
A	TYR222
A	SER254
A	LYS255

---

site_id	AD1
Number of Residues	2
Details	binding site for residue OLC A 316

Chain	Residue
A	ASN264
A	OLC302

---

site_id	AD2
Number of Residues	1
Details	binding site for residue GOL A 317

Chain	Residue
A	TYR76

---

site_id	AD3
Number of Residues	6
Details	binding site for residue NA A 318

Chain	Residue
A	VAL67
A	SER70
A	ALA71
A	ASN112
A	ILE115
A	ASP116

---

site_id	AD4
Number of Residues	2
Details	binding site for residue OLC B 301

Chain	Residue
B	VAL169
B	OLC303

---

site_id	AD5
Number of Residues	3
Details	binding site for residue OLC B 302

Chain	Residue
B	GLY171
B	SER175
B	LEU223

---

site_id	AD6
Number of Residues	3
Details	binding site for residue OLC B 303

Chain	Residue
B	TYR159
B	TRP170
B	OLC301

---

site_id	AD7
Number of Residues	1
Details	binding site for residue LFA B 304

Chain	Residue
B	ASN206

---

site_id	AD8
Number of Residues	1
Details	binding site for residue LFA B 305

Chain	Residue
B	THR216

---

site_id	AD9
Number of Residues	1
Details	binding site for residue LFA B 306

Chain	Residue
B	SER175

---

site_id	AE1
Number of Residues	5
Details	binding site for residue NA B 307

Chain	Residue
B	TYR25
B	THR83
B	PHE86
B	HOH443
C	ASP102

---

site_id	AE2
Number of Residues	3
Details	binding site for residue OLA B 309

Chain	Residue
B	OLA310
B	HOH411
C	OLA312

---

site_id	AE3
Number of Residues	5
Details	binding site for residue OLA B 310

Chain	Residue
A	LEU44
A	LEU48
B	OLA309
B	HOH409
E	OLA403

---

site_id	AE4
Number of Residues	2
Details	binding site for residue GOL B 311

Chain	Residue
B	PHE72
B	TYR76

---

site_id	AE5
Number of Residues	5
Details	binding site for residue NA B 312

Chain	Residue
B	VAL67
B	SER70
B	ALA71
B	ASN112
B	ASP116

---

site_id	AE6
Number of Residues	6
Details	binding site for residue OLC C 301

Chain	Residue
B	TYR45
B	ASN264
C	LEU63
C	ILE115
C	PHE122
C	OLC302

---

site_id	AE7
Number of Residues	5
Details	binding site for residue OLC C 302

Chain	Residue
B	ASN264
C	ARG139
C	TRP143
C	OLC301
C	LFA310

---

site_id	AE8
Number of Residues	4
Details	binding site for residue OLC C 303

Chain	Residue
C	TYR45
C	ASN264
D	LEU114
D	ILE115

---

site_id	AE9
Number of Residues	1
Details	binding site for residue OLC C 304

Chain	Residue
C	HIS180

---

site_id	AF1
Number of Residues	3
Details	binding site for residue OLC C 305

Chain	Residue
C	ASN163
C	THR165
C	OLC307

---

site_id	AF2
Number of Residues	3
Details	binding site for residue OLC C 306

Chain	Residue
C	GLY171
C	SER175
C	THR165

---

site_id	AF3
Number of Residues	4
Details	binding site for residue OLC C 307

Chain	Residue
C	TYR159
C	ASN163
C	TRP170
C	OLC305

---

site_id	AF4
Number of Residues	1
Details	binding site for residue LFA C 308

Chain	Residue
C	TRP183

---

site_id	AF5
Number of Residues	2
Details	binding site for residue LFA C 310

Chain	Residue
C	ARG139
C	OLC302

---

site_id	AF6
Number of Residues	5
Details	binding site for residue NA C 311

Chain	Residue
C	TYR25
C	THR83
C	PHE86
D	ASP102
D	HOH436

---

site_id	AF7
Number of Residues	4
Details	binding site for residue OLA C 312

Chain	Residue
B	OLA309
C	LEU44
D	OLA313
E	OLA401

---

site_id	AF8
Number of Residues	3
Details	binding site for residue GOL C 313

Chain	Residue
C	TYR76
C	HOH422
D	TYR76

---

site_id	AF9
Number of Residues	2
Details	binding site for residue OLC C 315

Chain	Residue
C	VAL260
C	ASN264

---

site_id	AG1
Number of Residues	5
Details	binding site for residue NA C 316

Chain	Residue
C	VAL67
C	SER70
C	ALA71
C	ASN112
C	ASP116

---

site_id	AG2
Number of Residues	5
Details	binding site for residue OLC D 302

Chain	Residue
D	ASN163
D	THR165
D	VAL169
D	TRP170
D	OLC304

---

site_id	AG3
Number of Residues	2
Details	binding site for residue OLC D 303

Chain	Residue
D	GLY171
D	SER175

---

site_id	AG4
Number of Residues	4
Details	binding site for residue OLC D 304

Chain	Residue
D	TYR159
D	ASN163
D	TRP170
D	OLC302

---

site_id	AG5
Number of Residues	1
Details	binding site for residue LFA D 305

Chain	Residue
D	LFA307

---

site_id	AG6
Number of Residues	2
Details	binding site for residue LFA D 306

Chain	Residue
D	ARG139
D	ASN140

---

site_id	AG7
Number of Residues	2
Details	binding site for residue LFA D 307

Chain	Residue
D	LFA305
D	LFA309

---

site_id	AG8
Number of Residues	3
Details	binding site for residue LFA D 308

Chain	Residue
D	TYR45
D	OLC312
E	LEU114

---

site_id	AG9
Number of Residues	2
Details	binding site for residue LFA D 309

Chain	Residue
D	THR216
D	LFA307

---

site_id	AH1
Number of Residues	5
Details	binding site for residue NA D 310

Chain	Residue
D	TYR25
D	THR83
D	PHE86
D	HOH437
E	ASP102

---

site_id	AH2
Number of Residues	3
Details	binding site for residue OLC D 312

Chain	Residue
D	ASN264
D	LFA308
E	ARG139

---

site_id	AH3
Number of Residues	5
Details	binding site for residue OLA D 313

Chain	Residue
C	OLA312
D	TYR76
E	TYR76
E	OLA401
E	OLA413

---

site_id	AH4
Number of Residues	6
Details	binding site for residue NA D 314

Chain	Residue
D	VAL67
D	SER70
D	ALA71
D	ASN112
D	ILE115
D	ASP116

---

site_id	AH5
Number of Residues	6
Details	binding site for residue OLA E 401

Chain	Residue
C	OLA312
D	LEU44
D	OLA313
E	OLA402
E	OLA403
E	OLA413

---

site_id	AH6
Number of Residues	5
Details	binding site for residue OLA E 402

Chain	Residue
E	LEU44
E	LEU48
E	OLA401
E	OLA403
E	OLA413

---

site_id	AH7
Number of Residues	3
Details	binding site for residue OLA E 403

Chain	Residue
B	OLA310
E	OLA401
E	OLA402

---

site_id	AH8
Number of Residues	1
Details	binding site for residue OLC E 404

Chain	Residue
E	ARG139

---

site_id	AH9
Number of Residues	2
Details	binding site for residue OLC E 406

Chain	Residue
E	ASN163
E	THR165

---

site_id	AI1
Number of Residues	2
Details	binding site for residue OLC E 407

Chain	Residue
E	TYR159
E	TRP170

---

site_id	AI2
Number of Residues	1
Details	binding site for residue LFA E 408

Chain	Residue
E	SER253

---

site_id	AI3
Number of Residues	2
Details	binding site for residue LFA E 409

Chain	Residue
E	LEU212
E	LFA410

---

site_id	AI4
Number of Residues	1
Details	binding site for residue LFA E 410

Chain	Residue
E	LFA409

---

site_id	AI5
Number of Residues	5
Details	binding site for residue NA E 412

Chain	Residue
A	ASP102
E	TYR25
E	THR83
E	PHE86
E	HOH537

---

site_id	AI6
Number of Residues	5
Details	binding site for residue OLA E 413

Chain	Residue
A	TYR76
D	OLA313
E	TYR76
E	OLA401
E	OLA402

---

site_id	AI7
Number of Residues	5
Details	binding site for residue NA E 415

Chain	Residue
E	VAL67
E	SER70
E	ALA71
E	ASN112
E	ASP116

---

site_id	AI8
Number of Residues	17
Details	binding site for Di-peptide RET B 308 and LYS B 255

Chain	Residue
B	TRP113
B	ASP116
B	LEU120
B	MET149
B	GLY171
B	SER174
B	PHE178
B	TRP215
B	TYR218
B	TYR222
B	ASP251
B	SER253
B	SER254
B	VAL256
B	ILE257
B	GLY259
B	HOH432

---

site_id	AI9
Number of Residues	16
Details	binding site for Di-peptide RET C 314 and LYS C 255

Chain	Residue
C	TRP113
C	ASP116
C	LEU120
C	MET149
C	GLY171
C	SER174
C	TRP215
C	TYR218
C	TYR222
C	ASP251
C	SER253
C	SER254
C	VAL256
C	ILE257
C	GLY259
C	HOH411

---

site_id	AJ1
Number of Residues	16
Details	binding site for Di-peptide RET D 311 and LYS D 255

Chain	Residue
D	TRP113
D	ASP116
D	LEU120
D	MET149
D	GLY171
D	SER174
D	TRP215
D	TYR218
D	TYR222
D	ASP251
D	SER253
D	SER254
D	VAL256
D	ILE257
D	GLY259
D	HOH432

---

site_id	AJ2
Number of Residues	16
Details	binding site for Di-peptide RET E 414 and LYS E 255

Chain	Residue
E	TRP113
E	ASP116
E	LEU120
E	MET149
E	GLY171
E	SER174
E	PHE178
E	TRP215
E	TYR218
E	TYR222
E	ASP251
E	SER253
E	SER254
E	VAL256
E	ILE257
E	GLY259

---