Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003908 | molecular_function | methylated-DNA-[protein]-cysteine S-methyltransferase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006259 | biological_process | DNA metabolic process |
| A | 0006281 | biological_process | DNA repair |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 201 |
| Chain | Residue |
| A | CYS5 |
| A | CYS24 |
| A | HIS29 |
| A | HIS85 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue OGQ A 202 |
| Chain | Residue |
| A | TYR158 |
| A | GLU159 |
| A | GLU159 |
| A | GLY160 |
| A | GLY161 |
| A | LEU162 |
| A | EDO203 |
| A | HOH332 |
| A | HOH338 |
| A | LEU134 |
| A | SER135 |
| A | PRO140 |
| A | CYS145 |
| A | TYR158 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 203 |
| Chain | Residue |
| A | GLU30 |
| A | ILE31 |
| A | ASN137 |
| A | PRO138 |
| A | OGQ202 |
| A | HOH313 |
Functional Information from PROSITE/UniProt
| site_id | PS00374 |
| Number of Residues | 7 |
| Details | MGMT Methylated-DNA--protein-cysteine methyltransferase active site. IPCHRVV |
| Chain | Residue | Details |
| A | ILE143-VAL149 | |
