Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6Y79

Cryo-EM structure of a respiratory complex I F89A mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0003954	molecular_function	NADH dehydrogenase activity
1	0005743	cellular_component	mitochondrial inner membrane
1	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
1	0009060	biological_process	aerobic respiration
1	0016020	cellular_component	membrane
1	0022904	biological_process	respiratory electron transport chain
1	0045271	cellular_component	respiratory chain complex I
1	1902600	biological_process	proton transmembrane transport
2	0005743	cellular_component	mitochondrial inner membrane
2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
2	0022904	biological_process	respiratory electron transport chain
2	0045271	cellular_component	respiratory chain complex I
2	1902600	biological_process	proton transmembrane transport
3	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
3	0022904	biological_process	respiratory electron transport chain
3	0031966	cellular_component	mitochondrial membrane
3	0045271	cellular_component	respiratory chain complex I
3	1902600	biological_process	proton transmembrane transport
4	0003954	molecular_function	NADH dehydrogenase activity
4	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
4	0009060	biological_process	aerobic respiration
4	0015990	biological_process	electron transport coupled proton transport
4	0022904	biological_process	respiratory electron transport chain
4	0031966	cellular_component	mitochondrial membrane
4	0042773	biological_process	ATP synthesis coupled electron transport
4	0045271	cellular_component	respiratory chain complex I
4	0048039	molecular_function	ubiquinone binding
5	0005743	cellular_component	mitochondrial inner membrane
5	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
5	0015990	biological_process	electron transport coupled proton transport
5	0022904	biological_process	respiratory electron transport chain
5	0042773	biological_process	ATP synthesis coupled electron transport
5	0045271	cellular_component	respiratory chain complex I
6	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
6	0022904	biological_process	respiratory electron transport chain
6	0031966	cellular_component	mitochondrial membrane
6	1902600	biological_process	proton transmembrane transport
8	0005739	cellular_component	mitochondrion
8	0005743	cellular_component	mitochondrial inner membrane
8	0005758	cellular_component	mitochondrial intermembrane space
8	0022904	biological_process	respiratory electron transport chain
8	0045271	cellular_component	respiratory chain complex I
9	0005743	cellular_component	mitochondrial inner membrane
9	0005758	cellular_component	mitochondrial intermembrane space
9	0022904	biological_process	respiratory electron transport chain
9	0032981	biological_process	mitochondrial respiratory chain complex I assembly
9	0045271	cellular_component	respiratory chain complex I
a	0005739	cellular_component	mitochondrion
a	0045271	cellular_component	respiratory chain complex I
A	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
A	0042773	biological_process	ATP synthesis coupled electron transport
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A	1902600	biological_process	proton transmembrane transport
B	0000166	molecular_function	nucleotide binding
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
B	0010181	molecular_function	FMN binding
B	0022904	biological_process	respiratory electron transport chain
B	0046872	molecular_function	metal ion binding
B	0051287	molecular_function	NAD binding
B	0051536	molecular_function	iron-sulfur cluster binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
B	1902600	biological_process	proton transmembrane transport
c	0005739	cellular_component	mitochondrion
c	0005743	cellular_component	mitochondrial inner membrane
c	0022900	biological_process	electron transport chain
c	0022904	biological_process	respiratory electron transport chain
c	0045271	cellular_component	respiratory chain complex I
C	0005743	cellular_component	mitochondrial inner membrane
C	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
C	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
C	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
C	0045271	cellular_component	respiratory chain complex I
C	0048038	molecular_function	quinone binding
C	0051287	molecular_function	NAD binding
C	1902600	biological_process	proton transmembrane transport
d	0005739	cellular_component	mitochondrion
d	0005743	cellular_component	mitochondrial inner membrane
d	0022904	biological_process	respiratory electron transport chain
d	0045271	cellular_component	respiratory chain complex I
D	0005743	cellular_component	mitochondrial inner membrane
D	0022904	biological_process	respiratory electron transport chain
D	0045271	cellular_component	respiratory chain complex I
E	0000166	molecular_function	nucleotide binding
E	0005739	cellular_component	mitochondrion
E	0006744	biological_process	ubiquinone biosynthetic process
E	0044877	molecular_function	protein-containing complex binding
f	0005743	cellular_component	mitochondrial inner membrane
f	0022904	biological_process	respiratory electron transport chain
f	0045271	cellular_component	respiratory chain complex I
F	0005743	cellular_component	mitochondrial inner membrane
F	0022904	biological_process	respiratory electron transport chain
F	0045271	cellular_component	respiratory chain complex I
G	0005739	cellular_component	mitochondrion
G	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
G	0016020	cellular_component	membrane
G	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
G	0045271	cellular_component	respiratory chain complex I
G	1902600	biological_process	proton transmembrane transport
h	0005743	cellular_component	mitochondrial inner membrane
h	0016020	cellular_component	membrane
h	0022904	biological_process	respiratory electron transport chain
h	0045271	cellular_component	respiratory chain complex I
H	0005743	cellular_component	mitochondrial inner membrane
H	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
H	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
H	0016491	molecular_function	oxidoreductase activity
H	0046872	molecular_function	metal ion binding
H	0051536	molecular_function	iron-sulfur cluster binding
H	0051537	molecular_function	2 iron, 2 sulfur cluster binding
H	0098796	cellular_component	membrane protein complex
H	1902494	cellular_component	catalytic complex
H	1902600	biological_process	proton transmembrane transport
I	0003954	molecular_function	NADH dehydrogenase activity
I	0005739	cellular_component	mitochondrion
I	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
I	0016020	cellular_component	membrane
I	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
I	0032981	biological_process	mitochondrial respiratory chain complex I assembly
I	0045271	cellular_component	respiratory chain complex I
I	0046872	molecular_function	metal ion binding
I	0051536	molecular_function	iron-sulfur cluster binding
I	0051539	molecular_function	4 iron, 4 sulfur cluster binding
J	0005743	cellular_component	mitochondrial inner membrane
J	0005744	cellular_component	TIM23 mitochondrial import inner membrane translocase complex
J	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
J	0008320	molecular_function	protein transmembrane transporter activity
J	0030150	biological_process	protein import into mitochondrial matrix
J	0045271	cellular_component	respiratory chain complex I
K	0005739	cellular_component	mitochondrion
K	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
K	0009060	biological_process	aerobic respiration
K	0015990	biological_process	electron transport coupled proton transport
K	0016491	molecular_function	oxidoreductase activity
K	0032981	biological_process	mitochondrial respiratory chain complex I assembly
K	0045271	cellular_component	respiratory chain complex I
K	0046872	molecular_function	metal ion binding
K	0048038	molecular_function	quinone binding
K	0051536	molecular_function	iron-sulfur cluster binding
K	0051539	molecular_function	4 iron, 4 sulfur cluster binding
L	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
L	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
L	0022904	biological_process	respiratory electron transport chain
L	0031966	cellular_component	mitochondrial membrane
L	0042773	biological_process	ATP synthesis coupled electron transport
L	0045271	cellular_component	respiratory chain complex I
L	1902600	biological_process	proton transmembrane transport
M	0005739	cellular_component	mitochondrion
M	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
M	0045271	cellular_component	respiratory chain complex I
M	0046872	molecular_function	metal ion binding
O	0000035	molecular_function	acyl binding
O	0000036	molecular_function	acyl carrier activity
O	0005739	cellular_component	mitochondrion
O	0006629	biological_process	lipid metabolic process
O	0006631	biological_process	fatty acid metabolic process
O	0006633	biological_process	fatty acid biosynthetic process
O	0099128	cellular_component	mitochondrial [2Fe-2S] assembly complex
P	0005743	cellular_component	mitochondrial inner membrane
P	0022904	biological_process	respiratory electron transport chain
P	0045271	cellular_component	respiratory chain complex I
Q	0000035	molecular_function	acyl binding
Q	0000036	molecular_function	acyl carrier activity
Q	0005739	cellular_component	mitochondrion
Q	0006629	biological_process	lipid metabolic process
Q	0006631	biological_process	fatty acid metabolic process
Q	0006633	biological_process	fatty acid biosynthetic process
Q	0099128	cellular_component	mitochondrial [2Fe-2S] assembly complex
R	0005743	cellular_component	mitochondrial inner membrane
R	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
R	0022904	biological_process	respiratory electron transport chain
R	0045271	cellular_component	respiratory chain complex I
U	0005743	cellular_component	mitochondrial inner membrane
U	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
U	0022904	biological_process	respiratory electron transport chain
U	0045271	cellular_component	respiratory chain complex I
W	0005739	cellular_component	mitochondrion
W	0005743	cellular_component	mitochondrial inner membrane
W	0016020	cellular_component	membrane
W	0022904	biological_process	respiratory electron transport chain
W	0045271	cellular_component	respiratory chain complex I
X	0045271	cellular_component	respiratory chain complex I
Y	0005739	cellular_component	mitochondrion
Y	0005743	cellular_component	mitochondrial inner membrane
Y	0016020	cellular_component	membrane
Y	0022900	biological_process	electron transport chain
Y	0022904	biological_process	respiratory electron transport chain
Y	0032981	biological_process	mitochondrial respiratory chain complex I assembly
Y	0045271	cellular_component	respiratory chain complex I
Z	0005739	cellular_component	mitochondrion
Z	0032981	biological_process	mitochondrial respiratory chain complex I assembly

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue SF4 A 801

Chain	Residue
A	HIS129
A	ASP132
A	CYS133
A	CYS136
A	GLN138
A	CYS142
A	LEU144
A	GLN145
A	GLY236

site_id	AC2
Number of Residues	8
Details	binding site for residue SF4 A 802

Chain	Residue
A	MET180
A	CYS183
A	CYS186
A	THR187
A	CYS189
A	CYS233
A	VAL235
A	LEU238

site_id	AC3
Number of Residues	6
Details	binding site for residue FES A 803

Chain	Residue
A	CYS69
A	TYR70
A	CYS80
A	ARG81
A	CYS83
A	CYS97

site_id	AC4
Number of Residues	8
Details	binding site for residue SF4 B 501

Chain	Residue
B	PRO225
B	SER380
B	CYS381
B	GLY382
B	GLN383
B	CYS384
B	CYS387
B	CYS427

site_id	AC5
Number of Residues	15
Details	binding site for residue FMN B 502

Chain	Residue
B	GLY88
B	LYS97
B	ASN118
B	ASP120
B	GLU121
B	TYR206
B	GLY209
B	GLU210
B	GLU211
B	VAL244
B	THR245
B	ASN246
B	THR249
B	ALA428
B	LEU429

site_id	AC6
Number of Residues	13
Details	binding site for residue NDP E 401

Chain	Residue
E	ASN62
E	GLY63
E	PHE64
E	LEU65
E	ARG85
E	LEU128
E	GLY130
E	ARG131
E	PHE138
E	PHE169
E	PHE179
E	LYS211
E	PHE213

site_id	AC7
Number of Residues	7
Details	binding site for residue FES H 301

Chain	Residue
H	CYS127
H	CYS132
H	CYS168
H	LEU169
H	ALA171
H	CYS172
H	MET177

site_id	AC8
Number of Residues	16
Details	binding site for residue 3PE I 501

Chain	Residue
1	PRO184
1	ILE188
1	PHE190
1	ILE191
1	PHE202
1	SER292
1	TRP295
1	VAL296
1	PHE303
1	PHE311
1	LEU319
C	ARG269
I	THR75
I	TYR77
g	PHE28
g	ILE32

site_id	AC9
Number of Residues	10
Details	binding site for residue SF4 I 502

Chain	Residue
I	HIS118
I	CYS140
I	ILE145
I	CYS169
I	ILE170
I	TYR171
I	CYS172
I	GLY173
I	CYS175
I	GLU186

site_id	AD1
Number of Residues	6
Details	binding site for residue SF4 I 503

Chain	Residue
I	CYS130
I	CYS133
I	LYS134
I	CYS136
I	ILE147
I	CYS179

site_id	AD2
Number of Residues	7
Details	binding site for residue 3PE J 201

Chain	Residue
J	ARG89
J	ASP93
J	GLY94
J	TRP95
J	TRP134
j	LMN101
4	T7X505

site_id	AD3
Number of Residues	16
Details	binding site for residue LMN J 202

Chain	Residue
2	LEU391
2	TYR396
2	ILE400
4	PHE177
4	VAL184
4	ASP205
J	TYR82
J	LYS92
J	ASP93
J	HIS97
J	GLY133
J	TRP134
J	ALA145
J	THR162
J	PHE163
J	TRP164

site_id	AD4
Number of Residues	10
Details	binding site for residue 3PE J 203

Chain	Residue
2	ILE265
5	LEU606
5	LEU620
5	ILE623
5	LEU630
5	VAL634
5	LEU646
5	ILE652
J	ALA43
J	ARG47

site_id	AD5
Number of Residues	7
Details	binding site for residue LMN J 204

Chain	Residue
J	VAL115
J	PRO116
a	LYS31
j	TYR48
j	THR49
j	ARG50
j	GLY53

site_id	AD6
Number of Residues	8
Details	binding site for residue SF4 K 301

Chain	Residue
C	ARG141
C	HIS226
K	ALA84
K	CYS85
K	CYS86
K	SER149
K	CYS150
K	CYS180

site_id	AD7
Number of Residues	4
Details	binding site for residue ZN M 201

Chain	Residue
M	CYS97
M	HIS110
M	CYS125
M	CYS128

site_id	AD8
Number of Residues	16
Details	binding site for residue ZMP O 201

Chain	Residue
O	ASP65
O	SER66
O	LEU67
P	THR25
P	PHE32
P	ILE56
P	GLU59
P	PHE60
P	HIS63
P	ARG64
P	GLN72
P	LEU75
P	GLY79
P	PHE96
P	TYR99
P	PHE100

site_id	AD9
Number of Residues	14
Details	binding site for residue ZMP Q 201

Chain	Residue
Q	SER89
Q	LEU90
R	PHE7
R	ASN11
R	LYS12
R	SER22
R	LYS46
R	PHE47
R	ASN50
R	ALA51
R	ILE53
R	LEU59
R	THR66
R	HIS69

site_id	AE1
Number of Residues	17
Details	binding site for residue 3PE S 501

Chain	Residue
4	ASN15
4	ARG16
4	3PE503
S	ASN113
b	PHE4
b	LEU7
b	SER11
b	GLY12
b	PHE15
b	PHE19
b	PRO28
b	ALA29
b	GLY30
b	TYR36
b	VAL37
b	VAL41
b	3PE201

site_id	AE2
Number of Residues	13
Details	binding site for residue PLC W 201

Chain	Residue
1	TRP295
I	LYS76
I	LEU79
I	ALA81
I	PHE84
I	LEU91
W	ARG26
W	GLY27
W	PHE28
W	ARG29
W	PRO30
W	TYR33
W	PLC202

site_id	AE3
Number of Residues	8
Details	binding site for residue PLC W 202

Chain	Residue
I	TYR88
W	ALA25
W	ARG26
W	GLY27
W	PHE28
W	TYR33
W	PLC201
Z	CDL201

site_id	AE4
Number of Residues	22
Details	binding site for residue CDL X 201

Chain	Residue
1	TYR332
2	ILE3
2	LEU4
2	CDL501
3	ASN85
3	TYR86
3	THR89
3	LEU92
6	PHE160
6	LEU163
X	PHE28
X	LYS29
X	PHE87
X	SER129
X	SER130
X	PRO154
X	TRP155
X	PHE158
X	VAL159
X	ASN160
g	PRO37
g	LEU41

site_id	AE5
Number of Residues	12
Details	binding site for residue CDL Z 201

Chain	Residue
1	PHE291
D	ALA2
D	ILE3
D	LEU8
I	LEU91
I	PHE95
W	PLC202
Z	SER17
Z	TRP21
Z	LEU24
Z	ARG25
Z	LEU28

site_id	AE6
Number of Residues	13
Details	binding site for residue 3PE a 201

Chain	Residue
5	GLN162
5	LYS165
5	SER166
5	LEU168
5	SER169
5	LEU172
5	MET173
5	PHE176
5	LEU238
5	ASN561
5	ILE565
a	PRO82
a	ASP83

site_id	AE7
Number of Residues	12
Details	binding site for residue 3PE b 201

Chain	Residue
2	TYR359
4	LEU11
4	PHE14
4	ASN15
4	LEU18
4	LEU147
4	3PE501
4	3PE504
S	3PE501
b	PHE19
b	LYS23
b	ALA29

site_id	AE8
Number of Residues	9
Details	binding site for residue 3PE i 101

Chain	Residue
4	PRO370
4	THR374
4	ILE377
4	CDL502
5	HIS112
5	ARG115
i	SER14
i	THR16
i	GLY18

site_id	AE9
Number of Residues	8
Details	binding site for residue LMN j 101

Chain	Residue
4	THR208
4	MET219
4	LEU272
4	TYR273
4	MET276
J	3PE201
j	TYR72
j	GLN73

site_id	AF1
Number of Residues	8
Details	binding site for residue PLC 1 401

Chain	Residue
1	THR330
1	PHE334
W	GLY42
W	PHE45
W	TYR46
W	LEU49
W	GLN53
g	TYR52

site_id	AF2
Number of Residues	11
Details	binding site for residue UQ9 1 402

Chain	Residue
1	LEU16
1	ALA20
1	GLU26
1	ALA50
1	ASP53
1	LEU57
1	PHE228
1	ARG297
K	TRP77
K	ILE106
K	ARG108

site_id	AF3
Number of Residues	10
Details	binding site for residue PLC 1 403

Chain	Residue
1	TYR21
1	ASN40
1	PHE41
1	VAL42
1	GLY43
1	TYR44
K	TRP70
h	LEU24
h	ASN25
h	ILE27

site_id	AF4
Number of Residues	15
Details	binding site for residue CDL 2 501

Chain	Residue
2	LEU4
2	ILE7
2	SER8
2	MET15
3	3PE201
X	LYS73
X	VAL77
X	THR79
X	MET80
X	PHE83
X	CDL201
g	ASN5
g	PHE8
g	TRP9
g	TYR15

site_id	AF5
Number of Residues	11
Details	binding site for residue T7X 2 502

Chain	Residue
2	SER437
2	VAL438
2	TYR441
2	PSC503
X	TRP59
X	LEU60
b	ARG25
b	TYR32
b	PHE38
b	SER39
b	ALA42

site_id	AF6
Number of Residues	16
Details	binding site for residue PSC 2 503

Chain	Residue
2	LEU36
2	SER40
2	TYR43
2	TYR67
2	MET70
2	TYR311
2	THR314
2	LEU378
2	GLY453
2	TYR456
2	ILE460
2	ILE463
2	PHE464
2	TYR467
2	T7X502
b	VAL53

site_id	AF7
Number of Residues	15
Details	binding site for residue T7X 2 504

Chain	Residue
2	TYR170
2	LEU199
2	ILE202
2	ALA203
2	LEU206
2	ASN256
2	SER257
2	LEU258
2	VAL259
5	ILE625
5	VAL632
5	LEU633
6	VAL103
6	SER107
L	PHE12

site_id	AF8
Number of Residues	16
Details	binding site for residue 3PE 3 201

Chain	Residue
1	GLY322
1	LEU325
2	CDL501
3	ILE99
3	VAL103
3	ILE106
3	ASN107
3	ASN109
g	ASN5
g	SER19
g	ARG23
g	LEU26
g	ALA29
g	PHE30
g	ALA31
g	ILE34

site_id	AF9
Number of Residues	11
Details	binding site for residue T7X 3 202

Chain	Residue
1	VAL55
3	ILE23
3	LEU24
3	LEU25
3	ALA26
3	VAL27
E	TRP305
E	TRP306
K	LEU64
K	ILE203
K	THR204

site_id	AG1
Number of Residues	10
Details	binding site for residue 3PE 4 501

Chain	Residue
2	ALA358
2	LEU362
4	PHE14
4	TYR28
4	ASN112
4	THR116
4	ALA143
4	PRO146
4	3PE503
b	3PE201

site_id	AG2
Number of Residues	21
Details	binding site for residue CDL 4 502

Chain	Residue
4	THR87
4	LEU90
4	PHE337
4	GLN371
4	TYR375
4	ILE448
4	LYS451
4	ASN455
4	ILE463
4	ILE464
4	MET471
5	CYS13
S	TYR169
S	ALA173
S	LEU176
S	LEU180
i	3PE101
n	TYR20
n	LYS23
n	TRP24
n	LEU31

site_id	AG3
Number of Residues	11
Details	binding site for residue 3PE 4 503

Chain	Residue
2	PHE452
2	PHE454
4	THR4
4	PHE60
4	ASN64
4	PHE66
4	LEU68
4	3PE501
4	3PE504
S	3PE501
b	GLY9

site_id	AG4
Number of Residues	13
Details	binding site for residue 3PE 4 504

Chain	Residue
2	PRO376
4	LEU3
4	PHE38
4	ASN56
4	PHE57
4	LEU68
4	VAL124
4	LEU126
4	LEU127
4	TRP130
4	LEU140
4	3PE503
b	3PE201

site_id	AG5
Number of Residues	7
Details	binding site for residue T7X 4 505

Chain	Residue
4	PHE165
4	TYR166
4	MET169
5	PRO589
5	CDL701
C	ALA36
J	3PE201

site_id	AG6
Number of Residues	14
Details	binding site for residue CDL 5 701

Chain	Residue
4	T7X505
5	ARG586
5	LEU587
5	GLY591
5	ILE592
5	ARG594
5	LEU595
5	SER655
J	PRO116
J	ALA117
J	GLY120
J	TRP121
J	LEU124
j	TYR48

site_id	AG7
Number of Residues	4
Details	binding site for residue PLC 5 702

Chain	Residue
5	LEU64
5	PHE65
i	TYR51
n	TYR35

site_id	AG8
Number of Residues	5
Details	binding site for residue PLC 5 703

Chain	Residue
5	LYS431
5	PHE536
5	ASN537
5	TYR547
R	TRP29

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDVVEVVMAI

Chain	Residue	Details
Q	ASP84-ILE99
O	ASP61-ILE76

site_id	PS00133
Number of Residues	11
Details	CARBOXYPEPT_ZN_2 Zinc carboxypeptidases, zinc-binding region 2 signature. HSIAGLFiFPW

Chain	Residue	Details
X	HIS145-TRP155

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaICP

Chain	Residue	Details
I	CYS130-PRO141
I	CYS169-PRO180

site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK

Chain	Residue	Details
C	LEU119-LYS130

site_id	PS00542
Number of Residues	22
Details	COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREayDMYgvffegHpdlRrIM

Chain	Residue	Details
G	GLU179-MET200

site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PryCYhdklaiaGnCRmC

Chain	Residue	Details
A	PRO66-CYS83

site_id	PS00642
Number of Residues	13
Details	COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPvCDqGGeCdLQ

Chain	Residue	Details
A	CYS133-GLN145

site_id	PS00643
Number of Residues	11
Details	COMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIhCtRCVrF

Chain	Residue	Details
A	ARG182-PHE192

site_id	PS00644
Number of Residues	16
Details	COMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GMGAYVCGEETSLIES

Chain	Residue	Details
B	GLY202-SER217

site_id	PS00645
Number of Residues	12
Details	COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG

Chain	Residue	Details
B	GLU379-GLY390

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQaFaDAVKLLlKE

Chain	Residue	Details
1	GLY46-GLU61

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLTESEseLVa.G

Chain	Residue	Details
1	PRO201-GLY214

site_id	PS01099
Number of Residues	19
Details	COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DnlFTlseveCLGaCvnAP

Chain	Residue	Details
H	ASP158-PRO176

site_id	PS01150
Number of Residues	17
Details	COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDVYvPgCPP

Chain	Residue	Details
K	GLY166-PRO182

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI16
Number of Residues	1123
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)