6Y2H
The crystal structure of human chloride intracellular channel protein 5
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005254 | molecular_function | chloride channel activity |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0007605 | biological_process | sensory perception of sound |
| B | 0005254 | molecular_function | chloride channel activity |
| B | 0006749 | biological_process | glutathione metabolic process |
| B | 0007605 | biological_process | sensory perception of sound |
| C | 0005254 | molecular_function | chloride channel activity |
| C | 0006749 | biological_process | glutathione metabolic process |
| C | 0007605 | biological_process | sensory perception of sound |
| D | 0005254 | molecular_function | chloride channel activity |
| D | 0006749 | biological_process | glutathione metabolic process |
| D | 0007605 | biological_process | sensory perception of sound |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue SCN A 301 |
| Chain | Residue |
| A | ALA114 |
| A | ALA184 |
| A | ASN187 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SCN A 302 |
| Chain | Residue |
| A | CYS32 |
| A | PRO33 |
| A | GLN36 |
| A | HIS193 |
| A | ALA232 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SCN A 303 |
| Chain | Residue |
| A | ASN112 |
| B | TYR222 |
| A | ARG109 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue SCN B 301 |
| Chain | Residue |
| B | THR228 |
| B | CYS231 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue SCN B 302 |
| Chain | Residue |
| B | ASN31 |
| B | CYS32 |
| B | GLN36 |
| B | HIS193 |
| B | ALA232 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue SCN B 303 |
| Chain | Residue |
| B | ASP225 |
| B | GLU226 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue SCN B 304 |
| Chain | Residue |
| A | LYS100 |
| B | HOH430 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue SCN B 305 |
| Chain | Residue |
| B | GLU89 |
| B | ASN112 |
| B | ASN187 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue SCN B 306 |
| Chain | Residue |
| B | VAL20 |
| B | PHE39 |
| B | THR230 |
| B | ALA232 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue SCN C 301 |
| Chain | Residue |
| C | ASN31 |
| C | CYS32 |
| C | PRO33 |
| C | GLN36 |
| C | HIS193 |
| C | ALA232 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue SCN C 302 |
| Chain | Residue |
| C | ARG37 |
| C | GLU89 |
| C | ASN112 |
| C | ASN187 |
| site_id | AD3 |
| Number of Residues | 1 |
| Details | binding site for residue SCN C 303 |
| Chain | Residue |
| C | HOH410 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue SCN D 301 |
| Chain | Residue |
| D | ALA114 |
| D | ALA184 |
| D | ASN187 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 80 |
| Details | Transmembrane: {"description":"Helical; Note=After insertion into the membrane","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Motif: {"description":"G-site","evidences":[{"source":"UniProtKB","id":"O00299","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
