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6Y2A

Crystal structure of HLA-B2705 complexed with the nona-peptide mQ

Functional Information from GO Data
ChainGOidnamespacecontents
B0006955biological_processimmune response
B0042612cellular_componentMHC class I protein complex
Functional Information from PDB Data
site_idAC1
Number of Residues11
Detailsbinding site for residue GOL A 301
ChainResidue
APHE8
BTYR63
BHOH201
ATYR27
AASP29
AASP30
AHOH403
AHOH418
AHOH571
AHOH670
AHOH695

site_idAC2
Number of Residues9
Detailsbinding site for residue GOL A 302
ChainResidue
ALYS146
ATRP147
AALA150
AHOH414
AHOH625
AHOH735
CPRO6
CILE7
CLYS8

site_idAC3
Number of Residues5
Detailsbinding site for residue GOL A 303
ChainResidue
AGLU163
AGLU166
ATRP167
AHOH759
AHOH772

site_idAC4
Number of Residues8
Detailsbinding site for residue GOL A 304
ChainResidue
AGLN115
AASP122
AGLU253
AARG256
AHOH482
AHOH488
AHOH560
AHOH566

site_idAC5
Number of Residues8
Detailsbinding site for residue GOL B 101
ChainResidue
BASP76
BTRP95
BASP96
BARG97
BHOH230
BHOH252
BHOH325
BHOH332

Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCHVQH
ChainResidueDetails
ATYR257-HIS263
BTYR78-HIS84

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
ChainResidueDetails
BGLN2

site_idSWS_FT_FI2
Number of Residues1
DetailsCARBOHYD: N-linked (Glc) (glycation) isoleucine; in hemodialysis-associated amyloidosis => ECO:0000269|PubMed:7918443
ChainResidueDetails
BILE1

site_idSWS_FT_FI3
Number of Residues6
DetailsCARBOHYD: N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:7918443
ChainResidueDetails
BLYS19
BLYS41
BLYS48
BLYS58
BLYS91
BLYS94

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PDB entries from 2024-11-06

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