6Y1U
Mycobacterium tuberculosis FtsZ-GDP in complex with 4-hydroxycoumarin
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue DMS A 401 |
| Chain | Residue |
| A | GLY202 |
| A | LEU203 |
| A | GLY263 |
| A | GLY264 |
| A | LEU267 |
| A | THR293 |
| A | VAL294 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue DMS A 402 |
| Chain | Residue |
| A | VAL54 |
| A | LEU89 |
| A | HOH586 |
| B | ASN22 |
| B | ARG26 |
| A | LYS12 |
| A | GLU36 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 403 |
| Chain | Residue |
| A | ARG119 |
| A | CYS155 |
| A | ASP156 |
| A | GLY219 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 404 |
| Chain | Residue |
| A | ALA9 |
| A | ASP94 |
| A | PHE208 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue DMS A 405 |
| Chain | Residue |
| B | LEU47 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 406 |
| Chain | Residue |
| A | ARG131 |
| A | VAL160 |
| A | PRO162 |
| A | GLU248 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue DMS A 407 |
| Chain | Residue |
| A | THR157 |
| A | ILE214 |
| A | MET215 |
| A | ALA218 |
| A | GLY256 |
| A | LEU258 |
| A | ILE308 |
| A | ALA310 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue DMS A 408 |
| Chain | Residue |
| A | ASP297 |
| site_id | AC9 |
| Number of Residues | 28 |
| Details | binding site for residue GDP A 409 |
| Chain | Residue |
| A | GLY17 |
| A | GLY18 |
| A | GLY19 |
| A | ASN22 |
| A | ALA68 |
| A | GLY101 |
| A | GLU102 |
| A | GLY104 |
| A | GLY105 |
| A | THR106 |
| A | GLY107 |
| A | PRO132 |
| A | GLU136 |
| A | ARG140 |
| A | PHE180 |
| A | ASP184 |
| A | LEU187 |
| A | HOH508 |
| A | HOH519 |
| A | HOH523 |
| A | HOH524 |
| A | HOH545 |
| A | HOH547 |
| A | HOH556 |
| A | HOH558 |
| A | HOH561 |
| A | HOH601 |
| A | HOH640 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue DMS B 401 |
| Chain | Residue |
| B | GLY202 |
| B | LEU203 |
| B | GLY263 |
| B | GLY264 |
| B | SER265 |
| B | THR293 |
| B | VAL294 |
| B | ILE295 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue DMS B 402 |
| Chain | Residue |
| A | ARG119 |
| B | ILE198 |
| B | THR199 |
| B | VAL206 |
| B | HOH565 |
| B | HOH576 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 403 |
| Chain | Residue |
| A | GLU36 |
| B | ASN22 |
| B | ASN25 |
| B | ARG26 |
| B | HOH519 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 404 |
| Chain | Residue |
| A | GLU87 |
| B | LEU176 |
| B | PHE180 |
| B | ASN205 |
| B | HOH514 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue DMS B 405 |
| Chain | Residue |
| B | THR220 |
| B | SER250 |
| B | ALA309 |
| B | GLY311 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue DMS B 406 |
| Chain | Residue |
| B | THR199 |
| B | THR200 |
| site_id | AD7 |
| Number of Residues | 9 |
| Details | binding site for residue DMS B 407 |
| Chain | Residue |
| B | THR130 |
| B | HOH516 |
| B | HOH687 |
| B | ALA100 |
| B | GLY101 |
| B | GLU102 |
| B | GLY103 |
| B | GLY104 |
| B | THR108 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue DMS B 408 |
| Chain | Residue |
| B | PRO132 |
| B | GLU136 |
| B | GLY137 |
| B | ARG139 |
| site_id | AD9 |
| Number of Residues | 1 |
| Details | binding site for residue DMS B 409 |
| Chain | Residue |
| B | TYR7 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 410 |
| Chain | Residue |
| B | ILE28 |
| B | PHE37 |
| B | ASP51 |
| B | ALA52 |
| B | ASP53 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 411 |
| Chain | Residue |
| B | ASN189 |
| B | GLN192 |
| B | ARG304 |
| B | HOH520 |
| B | HOH522 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue DMS B 412 |
| Chain | Residue |
| B | ARG131 |
| B | GLU248 |
| B | HOH504 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 413 |
| Chain | Residue |
| A | ASP53 |
| A | LYS55 |
| B | SER50 |
| B | ASP51 |
| B | HOH551 |
| site_id | AE5 |
| Number of Residues | 8 |
| Details | binding site for residue 4HC B 414 |
| Chain | Residue |
| B | ALA39 |
| B | LEU48 |
| B | MET49 |
| B | SER50 |
| B | LYS55 |
| B | LEU56 |
| B | ASP57 |
| B | HOH512 |
| site_id | AE6 |
| Number of Residues | 8 |
| Details | binding site for residue 4HC B 415 |
| Chain | Residue |
| B | GLU185 |
| B | ILE225 |
| B | GLY226 |
| B | SER227 |
| B | ARG304 |
| B | HOH548 |
| B | HOH555 |
| B | HOH612 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00909","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15342249","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23888039","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
