Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 601 |
| Chain | Residue |
| A | TYR295 |
| A | GLN340 |
| A | THR341 |
| A | GLU342 |
| A | VAL387 |
| A | VAL391 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 602 |
| Chain | Residue |
| A | PRO422 |
| A | HOH718 |
| C | THR69 |
| A | ASN261 |
| A | PRO419 |
| A | GLY421 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | binding site for residue CHO A 603 |
| Chain | Residue |
| A | TRP245 |
| A | ALA247 |
| A | TYR435 |
| A | MET436 |
| A | ARG437 |
| A | HOH715 |
| A | HOH750 |
| A | HOH824 |
| A | HOH856 |
| B | ALA290 |
| B | ILE310 |
| B | GLN312 |
| B | GLY314 |
| B | ARG390 |
| B | VAL391 |
| B | ARG392 |
| B | HOH777 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | binding site for residue CHO B 601 |
| Chain | Residue |
| A | ILE310 |
| A | GLN312 |
| A | GLY314 |
| A | ARG390 |
| A | VAL391 |
| A | ARG392 |
| A | HOH777 |
| B | TRP245 |
| B | ALA247 |
| B | TYR250 |
| B | TYR435 |
| B | ARG437 |
| B | HOH721 |
| B | HOH751 |
| B | HOH755 |
| B | HOH787 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 602 |
| Chain | Residue |
| B | GLN438 |
| B | ASP440 |
| B | GLU447 |
| B | HOH710 |
| B | HOH854 |
| B | HOH863 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO E 601 |
| Chain | Residue |
| E | TYR295 |
| E | GLN340 |
| E | THR341 |
| E | GLU342 |
| E | VAL387 |
| E | ARG390 |
| E | VAL391 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO E 602 |
| Chain | Residue |
| E | ASN261 |
| E | PRO419 |
| E | GLY421 |
| E | PRO422 |
| site_id | AC8 |
| Number of Residues | 14 |
| Details | binding site for residue CHO E 603 |
| Chain | Residue |
| E | TRP245 |
| E | ALA247 |
| E | TYR250 |
| E | TYR435 |
| E | ARG437 |
| E | HOH738 |
| E | HOH772 |
| E | HOH784 |
| F | ALA290 |
| F | GLN312 |
| F | GLY314 |
| F | ARG390 |
| F | VAL391 |
| F | ARG392 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | binding site for residue CHO F 900 |
| Chain | Residue |
| E | GLN312 |
| E | ARG390 |
| E | VAL391 |
| E | ARG392 |
| E | HOH730 |
| F | TRP245 |
| F | ALA247 |
| F | TYR435 |
| F | ARG437 |
| F | HOH1049 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 700 |
| Chain | Residue |
| A | LEU275 |
| A | LEU276 |
| C | SER50 |
| C | ILE51 |
| C | SER57 |
| C | ASN59 |
| C | ARG99 |
| site_id | AD2 |
| Number of Residues | 9 |
| Details | binding site for residue EDO D 700 |
| Chain | Residue |
| D | ASN59 |
| D | ARG99 |
| D | HOH806 |
| B | THR274 |
| B | LEU275 |
| B | LEU276 |
| D | SER50 |
| D | ILE51 |
| D | SER57 |
| site_id | AD3 |
| Number of Residues | 9 |
| Details | binding site for residue EDO G 700 |
| Chain | Residue |
| E | THR274 |
| E | LEU275 |
| E | LEU276 |
| G | SER50 |
| G | ILE51 |
| G | SER57 |
| G | ASN59 |
| G | ARG99 |
| G | HOH803 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue EDO H 700 |
| Chain | Residue |
| F | THR274 |
| F | LEU275 |
| F | LEU276 |
| H | SER50 |
| H | SER57 |
| H | ASN59 |
| H | ARG99 |
