6XW5

Crystal structure of murine norovirus P domain in complex with Nanobody NB-5820

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue EDO A 601

Chain	Residue
A	TYR295
A	VAL339
A	LYS351
A	THR353
A	VAL391
A	HOH726
A	HOH839

---

site_id	AC2
Number of Residues	5
Details	binding site for residue EDO A 602

Chain	Residue
A	ALA448
A	ILE449
A	ASP450
A	LEU258
A	ASP403

---

site_id	AC3
Number of Residues	9
Details	binding site for residue TRS A 603

Chain	Residue
A	TYR295
A	LYS296
A	PHE297
A	GLU303
A	SER383
A	ASP385
A	LEU386
D	ASP72
D	LYS75

---

site_id	AC4
Number of Residues	6
Details	binding site for residue EDO A 604

Chain	Residue
A	GLU456
A	SER459
A	TRP460
A	HOH722
B	SER459
B	SER463

---

site_id	AC5
Number of Residues	7
Details	binding site for residue EDO B 601

Chain	Residue
A	GLN340
A	THR343
B	ALA247
B	TYR250
B	TYR435
B	HOH754
B	HOH876

---

site_id	AC6
Number of Residues	6
Details	binding site for residue EDO B 602

Chain	Residue
B	LEU258
B	ASP403
B	ARG433
B	ALA448
B	ILE449
B	ASP450

---

site_id	AC7
Number of Residues	6
Details	binding site for residue EDO B 603

Chain	Residue
A	LEU239
B	PRO280
B	ILE281
B	SER282
B	TRP285
D	GLY101

---

site_id	AC8
Number of Residues	2
Details	binding site for residue EDO B 604

Chain	Residue
B	THR346
B	HOH703

---

site_id	AC9
Number of Residues	7
Details	binding site for residue EDO C 700

Chain	Residue
C	SER70
C	ARG71
C	ASP72
C	MET77
C	SER79
C	HOH822
C	HOH856

---

site_id	AD1
Number of Residues	5
Details	binding site for residue EDO C 701

Chain	Residue
C	TYR56
C	THR57
C	HOH818
C	HOH840
C	HOH850

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	276
Details	Region: {"description":"P2 sub-domain","evidences":[{"source":"PubMed","id":"22258242","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	136
Details	Region: {"description":"Interaction with host receptor CD300LF","evidences":[{"source":"PubMed","id":"30194229","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---