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6XUO

mature recombinant horse NGF

Functional Information from GO Data
ChainGOidnamespacecontents
A0005102molecular_functionsignaling receptor binding
A0005163molecular_functionnerve growth factor receptor binding
A0005576cellular_componentextracellular region
A0007169biological_processcell surface receptor protein tyrosine kinase signaling pathway
A0008021cellular_componentsynaptic vesicle
A0008083molecular_functiongrowth factor activity
A0021675biological_processnerve development
A0031904cellular_componentendosome lumen
A0038180biological_processnerve growth factor signaling pathway
A0043524biological_processnegative regulation of neuron apoptotic process
A0048812biological_processneuron projection morphogenesis
A0050804biological_processmodulation of chemical synaptic transmission
Functional Information from PDB Data
site_idAC1
Number of Residues3
Detailsbinding site for residue ZN A 201
ChainResidue
AASP24
AHIS84
AASP105

site_idAC2
Number of Residues3
Detailsbinding site for residue ZN A 202
ChainResidue
AGLU35
AGLU35
AGLU35

Functional Information from PROSITE/UniProt
site_idPS00248
Number of Residues14
DetailsNGF_1 Nerve growth factor family signature. GCRGIDskhWnSyC
ChainResidueDetails
AGLY67-CYS80

253795

PDB entries from 2026-05-20

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