6XUO

mature recombinant horse NGF

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004857	molecular_function	enzyme inhibitor activity
A	0005102	molecular_function	signaling receptor binding
A	0005163	molecular_function	nerve growth factor receptor binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0007169	biological_process	cell surface receptor protein tyrosine kinase signaling pathway
A	0008021	cellular_component	synaptic vesicle
A	0008083	molecular_function	growth factor activity
A	0021675	biological_process	nerve development
A	0030414	molecular_function	peptidase inhibitor activity
A	0031904	cellular_component	endosome lumen
A	0038180	biological_process	nerve growth factor signaling pathway
A	0043524	biological_process	negative regulation of neuron apoptotic process
A	0046872	molecular_function	metal ion binding
A	0048812	biological_process	neuron projection morphogenesis
A	0050804	biological_process	modulation of chemical synaptic transmission

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue ZN A 201

Chain	Residue
A	ASP24
A	HIS84
A	ASP105

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site_id	AC2
Number of Residues	3
Details	binding site for residue ZN A 202

Chain	Residue
A	GLU35
A	GLU35
A	GLU35

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Functional Information from PROSITE/UniProt

site_id	PS00248
Number of Residues	14
Details	NGF_1 Nerve growth factor family signature. GCRGIDskhWnSyC

Chain	Residue	Details
A	GLY67-CYS80

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