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6XU2

Human karyopherin RanBP5 (isoform-3)

Functional Information from GO Data
ChainGOidnamespacecontents
A0002753biological_processcytoplasmic pattern recognition receptor signaling pathway
A0003723molecular_functionRNA binding
A0005095molecular_functionGTPase inhibitor activity
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005643cellular_componentnuclear pore
A0005654cellular_componentnucleoplasm
A0005730cellular_componentnucleolus
A0005737cellular_componentcytoplasm
A0005794cellular_componentGolgi apparatus
A0005829cellular_componentcytosol
A0006606biological_processprotein import into nucleus
A0006607biological_processNLS-bearing protein import into nucleus
A0006610biological_processribosomal protein import into nucleus
A0006886biological_processintracellular protein transport
A0008139molecular_functionnuclear localization sequence binding
A0015031biological_processprotein transport
A0016020cellular_componentmembrane
A0031267molecular_functionsmall GTPase binding
A0031965cellular_componentnuclear membrane
A0042307biological_processpositive regulation of protein import into nucleus
A0045736biological_processnegative regulation of cyclin-dependent protein serine/threonine kinase activity
A0061608molecular_functionnuclear import signal receptor activity
A0071230biological_processcellular response to amino acid stimulus
Functional Information from PDB Data
site_idAC1
Number of Residues1
Detailsbinding site for residue NI A 1201
ChainResidue
AHIS765

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N-acetylalanine => ECO:0000269|Ref.7, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378, ECO:0007744|PubMed:25944712
ChainResidueDetails
AALA20

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
ChainResidueDetails
ASER845

227111

PDB entries from 2024-11-06

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