Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6XU1

Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with GTP, dAMPNPP and Mg

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue FE A 701

Chain	Residue
A	HIS167
A	HIS206
A	ASP207
A	ASP311
A	MG702
A	DZ4705
A	HOH866

site_id	AC2
Number of Residues	7
Details	binding site for residue MG A 702

Chain	Residue
A	FE701
A	DZ4705
A	HOH845
A	HOH865
A	HOH866
A	ASP207
A	HIS233

site_id	AC3
Number of Residues	5
Details	binding site for residue MG A 703

Chain	Residue
A	DZ4705
A	HOH805
A	HOH824
A	HOH858
A	HOH864

site_id	AC4
Number of Residues	3
Details	binding site for residue MG A 704

Chain	Residue
A	GTP706
A	HOH823
C	DZ4701

site_id	AC5
Number of Residues	29
Details	binding site for residue DZ4 A 705

Chain	Residue
A	GLN149
A	LEU150
A	ARG164
A	HIS167
A	ASP207
A	HIS210
A	ALA215
A	HIS233
A	ASP311
A	LYS312
A	TYR315
A	ASP319
A	ARG366
A	TYR374
A	GLN375
A	FE701
A	MG702
A	MG703
A	HOH805
A	HOH824
A	HOH828
A	HOH838
A	HOH839
A	HOH855
A	HOH857
A	HOH858
A	HOH864
A	HOH865
A	HOH866

site_id	AC6
Number of Residues	18
Details	binding site for residue GTP A 706

Chain	Residue
A	LYS116
A	VAL117
A	ILE118
A	ASP137
A	GLN142
A	ARG145
A	PHE165
A	MG704
A	HOH819
A	HOH823
A	HOH867
B	TYR155
B	VAL156
B	VAL378
B	ARG451
B	LYS455
C	LYS523
C	DZ4701

site_id	AC7
Number of Residues	17
Details	binding site for residue DZ4 A 707

Chain	Residue
A	ARG333
A	ARG352
A	LYS354
A	ASN358
A	LYS523
A	HOH811
A	HOH833
A	HOH869
C	VAL117
C	ASN119
C	MG705
C	GTP707
D	VAL156
D	PHE157
D	ARG372
D	HIS376
D	LYS377

site_id	AC8
Number of Residues	7
Details	binding site for residue FE B 701

Chain	Residue
B	HIS167
B	HIS206
B	ASP207
B	ASP311
B	MG702
B	DZ4705
B	HOH822

site_id	AC9
Number of Residues	7
Details	binding site for residue MG B 702

Chain	Residue
B	HOH850
B	ASP207
B	HIS233
B	FE701
B	DZ4705
B	HOH822
B	HOH849

site_id	AD1
Number of Residues	5
Details	binding site for residue MG B 703

Chain	Residue
B	DZ4705
B	HOH829
B	HOH842
B	HOH848
B	HOH877

site_id	AD2
Number of Residues	3
Details	binding site for residue MG B 704

Chain	Residue
B	GTP706
B	HOH818
D	DZ4701

site_id	AD3
Number of Residues	28
Details	binding site for residue DZ4 B 705

Chain	Residue
B	GLN149
B	LEU150
B	ARG164
B	HIS167
B	ASP207
B	HIS210
B	ALA215
B	HIS233
B	ASP311
B	LYS312
B	TYR315
B	ASP319
B	ARG366
B	TYR374
B	GLN375
B	FE701
B	MG702
B	MG703
B	HOH816
B	HOH822
B	HOH829
B	HOH837
B	HOH840
B	HOH842
B	HOH848
B	HOH849
B	HOH877
B	HOH894

site_id	AD4
Number of Residues	15
Details	binding site for residue GTP B 706

Chain	Residue
A	TYR155
A	VAL156
A	ARG451
A	LYS455
B	LYS116
B	VAL117
B	ILE118
B	ASP137
B	GLN142
B	ARG145
B	PHE165
B	MG704
B	HOH818
D	LYS523
D	DZ4701

site_id	AD5
Number of Residues	18
Details	binding site for residue DZ4 C 701

Chain	Residue
A	VAL117
A	ASN119
A	MG704
A	GTP706
A	HOH823
B	VAL156
B	PHE157
B	ARG372
B	HIS376
B	LYS377
C	ARG333
C	ARG352
C	LYS354
C	ASN358
C	LYS523
C	HOH807
C	HOH856
C	HOH872

site_id	AD6
Number of Residues	7
Details	binding site for residue FE C 702

Chain	Residue
C	HIS167
C	HIS206
C	ASP207
C	ASP311
C	MG703
C	DZ4706
C	HOH825

site_id	AD7
Number of Residues	7
Details	binding site for residue MG C 703

Chain	Residue
C	ASP207
C	HIS233
C	FE702
C	DZ4706
C	HOH825
C	HOH832
C	HOH841

site_id	AD8
Number of Residues	5
Details	binding site for residue MG C 704

Chain	Residue
C	DZ4706
C	HOH808
C	HOH826
C	HOH860
C	HOH878

site_id	AD9
Number of Residues	3
Details	binding site for residue MG C 705

Chain	Residue
A	DZ4707
A	HOH811
C	GTP707

site_id	AE1
Number of Residues	29
Details	binding site for residue DZ4 C 706

Chain	Residue
C	GLN149
C	LEU150
C	ARG164
C	HIS167
C	ASP207
C	HIS210
C	ALA215
C	HIS233
C	ASP311
C	LYS312
C	TYR315
C	ASP319
C	ARG366
C	TYR374
C	FE702
C	MG703
C	MG704
C	HOH808
C	HOH809
C	HOH813
C	HOH819
C	HOH825
C	HOH826
C	HOH832
C	HOH851
C	HOH860
C	HOH878
C	HOH885
C	HOH904

site_id	AE2
Number of Residues	16
Details	binding site for residue GTP C 707

Chain	Residue
A	LYS523
A	DZ4707
A	HOH811
C	LYS116
C	VAL117
C	ILE118
C	ASP137
C	GLN142
C	ARG145
C	PHE165
C	MG705
D	TYR155
D	VAL156
D	VAL378
D	ARG451
D	LYS455

site_id	AE3
Number of Residues	17
Details	binding site for residue DZ4 C 708

Chain	Residue
B	ARG333
B	ARG352
B	LYS354
B	ASN358
B	LYS523
C	VAL156
C	PHE157
C	ARG372
C	HIS376
C	LYS377
C	HOH835
C	HOH893
D	VAL117
D	ASN119
D	MG705
D	GTP707
D	HOH812

site_id	AE4
Number of Residues	17
Details	binding site for residue DZ4 D 701

Chain	Residue
A	VAL156
A	PHE157
A	ARG372
A	HIS376
A	LYS377
B	VAL117
B	ASN119
B	MG704
B	GTP706
B	HOH818
D	ARG333
D	ARG352
D	LYS354
D	ASN358
D	LYS523
D	HOH842
D	HOH855

site_id	AE5
Number of Residues	6
Details	binding site for residue FE D 702

Chain	Residue
D	HIS167
D	HIS206
D	ASP207
D	ASP311
D	DZ4706
D	HOH847

site_id	AE6
Number of Residues	6
Details	binding site for residue MG D 703

Chain	Residue
D	ASP207
D	HIS233
D	DZ4706
D	HOH822
D	HOH840
D	HOH847

site_id	AE7
Number of Residues	5
Details	binding site for residue MG D 704

Chain	Residue
D	DZ4706
D	HOH809
D	HOH830
D	HOH841
D	HOH872

site_id	AE8
Number of Residues	4
Details	binding site for residue MG D 705

Chain	Residue
C	DZ4708
D	LYS116
D	GTP707
D	HOH812

site_id	AE9
Number of Residues	28
Details	binding site for residue DZ4 D 706

Chain	Residue
D	GLN149
D	LEU150
D	ARG164
D	HIS167
D	ASP207
D	HIS210
D	ALA215
D	HIS233
D	ASP311
D	LYS312
D	TYR315
D	ASP319
D	ARG366
D	TYR374
D	GLN375
D	FE702
D	MG703
D	MG704
D	HOH809
D	HOH822
D	HOH824
D	HOH829
D	HOH830
D	HOH833
D	HOH841
D	HOH847
D	HOH870
D	HOH872

site_id	AF1
Number of Residues	16
Details	binding site for residue GTP D 707

Chain	Residue
B	LYS523
C	TYR155
C	VAL156
C	VAL378
C	ARG451
C	LYS455
C	DZ4708
D	LYS116
D	VAL117
D	ILE118
D	ASP137
D	GLN142
D	ARG145
D	PHE165
D	MG705
D	HOH812

site_id	AF2
Number of Residues	4
Details	binding site for residue MG D 708

Chain	Residue
D	ASN504
D	HOH802
D	HOH894
D	HOH897

site_id	AF3
Number of Residues	7
Details	binding site for residue FE E 701

Chain	Residue
E	HIS167
E	HIS206
E	ASP207
E	ASP311
E	MG702
E	DZ4705
E	HOH837

site_id	AF4
Number of Residues	7
Details	binding site for residue MG E 702

Chain	Residue
E	ASP207
E	HIS233
E	FE701
E	DZ4705
E	HOH826
E	HOH827
E	HOH837

site_id	AF5
Number of Residues	5
Details	binding site for residue MG E 703

Chain	Residue
E	DZ4705
E	HOH809
E	HOH822
E	HOH847
E	HOH852

site_id	AF6
Number of Residues	3
Details	binding site for residue MG E 704

Chain	Residue
E	GTP706
E	HOH811
G	DZ4701

site_id	AF7
Number of Residues	26
Details	binding site for residue DZ4 E 705

Chain	Residue
E	GLN149
E	LEU150
E	ARG164
E	HIS167
E	ASP207
E	HIS210
E	ALA215
E	HIS233
E	ASP311
E	LYS312
E	TYR315
E	ASP319
E	ARG366
E	TYR374
E	GLN375
E	FE701
E	MG702
E	MG703
E	HOH809
E	HOH821
E	HOH822
E	HOH827
E	HOH837
E	HOH847
E	HOH852
E	HOH853

site_id	AF8
Number of Residues	17
Details	binding site for residue GTP E 706

Chain	Residue
E	LYS116
E	VAL117
E	ILE118
E	ASP137
E	GLN142
E	ARG145
E	PHE165
E	MG704
E	HOH811
E	HOH825
F	TYR155
F	VAL156
F	VAL378
F	ARG451
F	LYS455
G	LYS523
G	DZ4701

site_id	AF9
Number of Residues	16
Details	binding site for residue GTP E 707

Chain	Residue
E	TYR155
E	VAL156
E	VAL378
E	ARG451
E	LYS455
F	LYS116
F	VAL117
F	ILE118
F	ASP137
F	GLN142
F	ARG145
F	PHE165
F	MG704
H	LYS523
H	DZ4701
H	HOH812

site_id	AG1
Number of Residues	15
Details	binding site for residue DZ4 E 708

Chain	Residue
E	ARG333
E	ARG352
E	LYS354
E	ASN358
E	LYS523
G	VAL117
G	ASN119
G	MG705
G	GTP707
G	HOH826
H	VAL156
H	PHE157
H	ARG372
H	HIS376
H	LYS377

site_id	AG2
Number of Residues	7
Details	binding site for residue FE F 701

Chain	Residue
F	HIS167
F	HIS206
F	ASP207
F	ASP311
F	MG702
F	DZ4705
F	HOH869

site_id	AG3
Number of Residues	7
Details	binding site for residue MG F 702

Chain	Residue
F	ASP207
F	HIS233
F	FE701
F	DZ4705
F	HOH843
F	HOH859
F	HOH869

site_id	AG4
Number of Residues	5
Details	binding site for residue MG F 703

Chain	Residue
F	DZ4705
F	HOH824
F	HOH855
F	HOH864
F	HOH866

site_id	AG5
Number of Residues	4
Details	binding site for residue MG F 704

Chain	Residue
E	GTP707
F	LYS116
H	DZ4701
H	HOH812

site_id	AG6
Number of Residues	30
Details	binding site for residue DZ4 F 705

Chain	Residue
F	GLN149
F	LEU150
F	ARG164
F	HIS167
F	ASP207
F	HIS210
F	ALA215
F	HIS233
F	ASP311
F	LYS312
F	TYR315
F	ASP319
F	ARG366
F	TYR374
F	GLN375
F	FE701
F	MG702
F	MG703
F	HOH812
F	HOH824
F	HOH825
F	HOH837
F	HOH855
F	HOH859
F	HOH864
F	HOH866
F	HOH869
F	HOH871
F	HOH881
F	HOH901

site_id	AG7
Number of Residues	17
Details	binding site for residue DZ4 F 706

Chain	Residue
F	ARG333
F	ARG352
F	LYS354
F	ASN358
F	LYS523
F	HOH820
F	HOH845
F	HOH878
G	VAL156
G	PHE157
G	ARG372
G	HIS376
G	LYS377
H	VAL117
H	ASN119
H	MG705
H	GTP707

site_id	AG8
Number of Residues	17
Details	binding site for residue DZ4 G 701

Chain	Residue
E	VAL117
E	ASN119
E	MG704
E	GTP706
E	HOH811
F	VAL156
F	PHE157
F	ARG372
F	HIS376
F	LYS377
G	ARG333
G	ARG352
G	LYS354
G	ASN358
G	LYS523
G	HOH872
G	HOH879

site_id	AG9
Number of Residues	7
Details	binding site for residue FE G 702

Chain	Residue
G	HIS167
G	HIS206
G	ASP207
G	ASP311
G	MG703
G	DZ4706
G	HOH847

site_id	AH1
Number of Residues	7
Details	binding site for residue MG G 703

Chain	Residue
G	ASP207
G	HIS233
G	FE702
G	DZ4706
G	HOH847
G	HOH862
G	HOH866

site_id	AH2
Number of Residues	5
Details	binding site for residue MG G 704

Chain	Residue
G	DZ4706
G	HOH808
G	HOH827
G	HOH855
G	HOH885

site_id	AH3
Number of Residues	4
Details	binding site for residue MG G 705

Chain	Residue
E	DZ4708
G	LYS116
G	GTP707
G	HOH826

site_id	AH4
Number of Residues	29
Details	binding site for residue DZ4 G 706

Chain	Residue
G	GLN149
G	LEU150
G	ARG164
G	HIS167
G	ASP207
G	HIS210
G	ALA215
G	HIS233
G	ASP311
G	LYS312
G	TYR315
G	ASP319
G	ARG366
G	TYR374
G	GLN375
G	FE702
G	MG703
G	MG704
G	HOH803
G	HOH808
G	HOH827
G	HOH836
G	HOH847
G	HOH850
G	HOH852
G	HOH855
G	HOH862
G	HOH874
G	HOH885

site_id	AH5
Number of Residues	16
Details	binding site for residue GTP G 707

Chain	Residue
E	LYS523
E	DZ4708
G	LYS116
G	VAL117
G	ILE118
G	ASP137
G	GLN142
G	ARG145
G	PHE165
G	MG705
G	HOH826
H	TYR155
H	VAL156
H	VAL378
H	ARG451
H	LYS455

site_id	AH6
Number of Residues	16
Details	binding site for residue DZ4 H 701

Chain	Residue
E	VAL156
E	PHE157
E	ARG372
E	HIS376
E	LYS377
E	GTP707
E	HOH841
F	VAL117
F	ASN119
F	MG704
H	ARG333
H	ARG352
H	LYS354
H	ASN358
H	LYS523
H	HOH812

site_id	AH7
Number of Residues	7
Details	binding site for residue FE H 702

Chain	Residue
H	HIS167
H	HIS206
H	ASP207
H	ASP311
H	MG703
H	DZ4706
H	HOH845

site_id	AH8
Number of Residues	7
Details	binding site for residue MG H 703

Chain	Residue
H	ASP207
H	HIS233
H	FE702
H	DZ4706
H	HOH833
H	HOH835
H	HOH845

site_id	AH9
Number of Residues	5
Details	binding site for residue MG H 704

Chain	Residue
H	DZ4706
H	HOH804
H	HOH808
H	HOH817
H	HOH826

site_id	AI1
Number of Residues	3
Details	binding site for residue MG H 705

Chain	Residue
F	DZ4706
F	HOH878
H	GTP707

site_id	AI2
Number of Residues	28
Details	binding site for residue DZ4 H 706

Chain	Residue
H	GLN149
H	LEU150
H	ARG164
H	HIS167
H	ASP207
H	HIS210
H	ALA215
H	HIS233
H	ASP311
H	LYS312
H	TYR315
H	ASP319
H	ARG366
H	TYR374
H	GLN375
H	FE702
H	MG703
H	MG704
H	HOH804
H	HOH806
H	HOH807
H	HOH808
H	HOH821
H	HOH825
H	HOH826
H	HOH835
H	HOH843
H	HOH845

site_id	AI3
Number of Residues	16
Details	binding site for residue GTP H 707

Chain	Residue
F	LYS523
F	DZ4706
F	HOH878
G	TYR155
G	VAL156
G	VAL378
G	ARG451
G	LYS455
H	LYS116
H	VAL117
H	ILE118
H	ASP137
H	GLN142
H	ARG145
H	PHE165
H	MG705

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: ACT_SITE => ECO:0000305\|PubMed:22056990

Chain	Residue	Details
A	HIS233
B	HIS233
C	HIS233
D	HIS233
E	HIS233
F	HIS233
G	HIS233
H	HIS233

site_id	SWS_FT_FI2
Number of Residues	40
Details	BINDING: in chain B => ECO:0000269\|PubMed:25267621, ECO:0007744\|PDB:4TNP, ECO:0007744\|PDB:4TNQ, ECO:0007744\|PDB:4TNR, ECO:0007744\|PDB:4TNX

Chain	Residue	Details
A	LYS116
B	ARG145
C	LYS116
C	VAL117
C	ASP137
C	GLN142
C	ARG145
D	LYS116
D	VAL117
D	ASP137
D	GLN142
A	VAL117
D	ARG145
E	LYS116
E	VAL117
E	ASP137
E	GLN142
E	ARG145
F	LYS116
F	VAL117
F	ASP137
F	GLN142
A	ASP137
F	ARG145
G	LYS116
G	VAL117
G	ASP137
G	GLN142
G	ARG145
H	LYS116
H	VAL117
H	ASP137
H	GLN142
A	GLN142
H	ARG145
A	ARG145
B	LYS116
B	VAL117
B	ASP137
B	GLN142

site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: in chain B => ECO:0000269\|PubMed:25267621, ECO:0007744\|PDB:4TNQ

Chain	Residue	Details
A	ASN119
B	ASN119
C	ASN119
D	ASN119
E	ASN119
F	ASN119
G	ASN119
H	ASN119

site_id	SWS_FT_FI4
Number of Residues	64
Details	BINDING: BINDING => ECO:0000269\|PubMed:25267621, ECO:0007744\|PDB:4TNQ

Chain	Residue	Details
A	GLN149
B	ARG164
B	HIS210
B	ALA215
B	LYS312
B	TYR315
B	ASP319
B	GLN375
C	GLN149
C	ARG164
C	HIS210
A	ARG164
C	ALA215
C	LYS312
C	TYR315
C	ASP319
C	GLN375
D	GLN149
D	ARG164
D	HIS210
D	ALA215
D	LYS312
A	HIS210
D	TYR315
D	ASP319
D	GLN375
E	GLN149
E	ARG164
E	HIS210
E	ALA215
E	LYS312
E	TYR315
E	ASP319
A	ALA215
E	GLN375
F	GLN149
F	ARG164
F	HIS210
F	ALA215
F	LYS312
F	TYR315
F	ASP319
F	GLN375
G	GLN149
A	LYS312
G	ARG164
G	HIS210
G	ALA215
G	LYS312
G	TYR315
G	ASP319
G	GLN375
H	GLN149
H	ARG164
H	HIS210
A	TYR315
H	ALA215
H	LYS312
H	TYR315
H	ASP319
H	GLN375
A	ASP319
A	GLN375
B	GLN149

site_id	SWS_FT_FI5
Number of Residues	56
Details	BINDING: BINDING => ECO:0000269\|PubMed:24141705, ECO:0007744\|PDB:4BZB

Chain	Residue	Details
A	LEU150
B	HIS206
B	ASP207
B	ASP311
B	ARG366
B	TYR374
C	LEU150
C	HIS167
C	HIS206
C	ASP207
C	ASP311
A	HIS167
C	ARG366
C	TYR374
D	LEU150
D	HIS167
D	HIS206
D	ASP207
D	ASP311
D	ARG366
D	TYR374
E	LEU150
A	HIS206
E	HIS167
E	HIS206
E	ASP207
E	ASP311
E	ARG366
E	TYR374
F	LEU150
F	HIS167
F	HIS206
F	ASP207
A	ASP207
F	ASP311
F	ARG366
F	TYR374
G	LEU150
G	HIS167
G	HIS206
G	ASP207
G	ASP311
G	ARG366
G	TYR374
A	ASP311
H	LEU150
H	HIS167
H	HIS206
H	ASP207
H	ASP311
H	ARG366
H	TYR374
A	ARG366
A	TYR374
B	LEU150
B	HIS167

site_id	SWS_FT_FI6
Number of Residues	32
Details	BINDING: in chain C => ECO:0000269\|PubMed:25267621, ECO:0007744\|PDB:4TNQ

Chain	Residue	Details
A	VAL156
C	ARG372
C	HIS376
C	LYS377
D	VAL156
D	ARG372
D	HIS376
D	LYS377
E	VAL156
E	ARG372
E	HIS376
A	ARG372
E	LYS377
F	VAL156
F	ARG372
F	HIS376
F	LYS377
G	VAL156
G	ARG372
G	HIS376
G	LYS377
H	VAL156
A	HIS376
H	ARG372
H	HIS376
H	LYS377
A	LYS377
B	VAL156
B	ARG372
B	HIS376
B	LYS377
C	VAL156

site_id	SWS_FT_FI7
Number of Residues	24
Details	BINDING: in chain A => ECO:0000269\|PubMed:25267621, ECO:0007744\|PDB:4TNQ

Chain	Residue	Details
A	ARG333
D	ARG333
D	ARG352
D	LYS354
E	ARG333
E	ARG352
E	LYS354
F	ARG333
F	ARG352
F	LYS354
G	ARG333
A	ARG352
G	ARG352
G	LYS354
H	ARG333
H	ARG352
H	LYS354
A	LYS354
B	ARG333
B	ARG352
B	LYS354
C	ARG333
C	ARG352
C	LYS354

site_id	SWS_FT_FI8
Number of Residues	8
Details	BINDING: in chain A => ECO:0000269\|PubMed:24141705, ECO:0000269\|PubMed:25267621, ECO:0007744\|PDB:4BZB, ECO:0007744\|PDB:4TNX

Chain	Residue	Details
A	ASN358
B	ASN358
C	ASN358
D	ASN358
E	ASN358
F	ASN358
G	ASN358
H	ASN358

site_id	SWS_FT_FI9
Number of Residues	16
Details	BINDING: in chain C => ECO:0000269\|PubMed:25267621, ECO:0007744\|PDB:4TNP, ECO:0007744\|PDB:4TNQ, ECO:0007744\|PDB:4TNR, ECO:0007744\|PDB:4TNX

Chain	Residue	Details
A	ARG451
E	LYS455
F	ARG451
F	LYS455
G	ARG451
G	LYS455
H	ARG451
H	LYS455
A	LYS455
B	ARG451
B	LYS455
C	ARG451
C	LYS455
D	ARG451
D	LYS455
E	ARG451

site_id	SWS_FT_FI10
Number of Residues	8
Details	BINDING: in chain A => ECO:0000269\|PubMed:25267621, ECO:0007744\|PDB:4TNP, ECO:0007744\|PDB:4TNQ, ECO:0007744\|PDB:4TNR, ECO:0007744\|PDB:4TNX

Chain	Residue	Details
A	LYS523
B	LYS523
C	LYS523
D	LYS523
E	LYS523
F	LYS523
G	LYS523
H	LYS523

site_id	SWS_FT_FI11
Number of Residues	8
Details	MOD_RES: Phosphothreonine; by CDK1 => ECO:0000269\|PubMed:23601106, ECO:0000269\|PubMed:23602554, ECO:0000269\|PubMed:26294762, ECO:0000269\|PubMed:26431200, ECO:0000269\|PubMed:29610582, ECO:0000269\|PubMed:29670289, ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:18691976, ECO:0007744\|PubMed:19369195, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
A	THR592
B	THR592
C	THR592
D	THR592
E	THR592
F	THR592
G	THR592
H	THR592

site_id	SWS_FT_FI12
Number of Residues	40
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
A	LYS467
B	LYS622
C	LYS467
C	LYS469
C	LYS492
C	LYS622
D	LYS467
D	LYS469
D	LYS492
D	LYS622
E	LYS467
E	LYS469
E	LYS492
E	LYS622
F	LYS467
F	LYS469
F	LYS492
A	LYS469
F	LYS622
G	LYS467
G	LYS469
G	LYS492
G	LYS622
H	LYS467
H	LYS469
H	LYS492
A	LYS492
H	LYS622
A	LYS622
B	LYS467
B	LYS469
B	LYS492

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)