6XU1
Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with GTP, dAMPNPP and Mg
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue FE A 701 |
| Chain | Residue |
| A | HIS167 |
| A | HIS206 |
| A | ASP207 |
| A | ASP311 |
| A | MG702 |
| A | DZ4705 |
| A | HOH866 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 702 |
| Chain | Residue |
| A | FE701 |
| A | DZ4705 |
| A | HOH845 |
| A | HOH865 |
| A | HOH866 |
| A | ASP207 |
| A | HIS233 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 703 |
| Chain | Residue |
| A | DZ4705 |
| A | HOH805 |
| A | HOH824 |
| A | HOH858 |
| A | HOH864 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 704 |
| Chain | Residue |
| A | GTP706 |
| A | HOH823 |
| C | DZ4701 |
| site_id | AC5 |
| Number of Residues | 29 |
| Details | binding site for residue DZ4 A 705 |
| Chain | Residue |
| A | GLN149 |
| A | LEU150 |
| A | ARG164 |
| A | HIS167 |
| A | ASP207 |
| A | HIS210 |
| A | ALA215 |
| A | HIS233 |
| A | ASP311 |
| A | LYS312 |
| A | TYR315 |
| A | ASP319 |
| A | ARG366 |
| A | TYR374 |
| A | GLN375 |
| A | FE701 |
| A | MG702 |
| A | MG703 |
| A | HOH805 |
| A | HOH824 |
| A | HOH828 |
| A | HOH838 |
| A | HOH839 |
| A | HOH855 |
| A | HOH857 |
| A | HOH858 |
| A | HOH864 |
| A | HOH865 |
| A | HOH866 |
| site_id | AC6 |
| Number of Residues | 18 |
| Details | binding site for residue GTP A 706 |
| Chain | Residue |
| A | LYS116 |
| A | VAL117 |
| A | ILE118 |
| A | ASP137 |
| A | GLN142 |
| A | ARG145 |
| A | PHE165 |
| A | MG704 |
| A | HOH819 |
| A | HOH823 |
| A | HOH867 |
| B | TYR155 |
| B | VAL156 |
| B | VAL378 |
| B | ARG451 |
| B | LYS455 |
| C | LYS523 |
| C | DZ4701 |
| site_id | AC7 |
| Number of Residues | 17 |
| Details | binding site for residue DZ4 A 707 |
| Chain | Residue |
| A | ARG333 |
| A | ARG352 |
| A | LYS354 |
| A | ASN358 |
| A | LYS523 |
| A | HOH811 |
| A | HOH833 |
| A | HOH869 |
| C | VAL117 |
| C | ASN119 |
| C | MG705 |
| C | GTP707 |
| D | VAL156 |
| D | PHE157 |
| D | ARG372 |
| D | HIS376 |
| D | LYS377 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue FE B 701 |
| Chain | Residue |
| B | HIS167 |
| B | HIS206 |
| B | ASP207 |
| B | ASP311 |
| B | MG702 |
| B | DZ4705 |
| B | HOH822 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue MG B 702 |
| Chain | Residue |
| B | HOH850 |
| B | ASP207 |
| B | HIS233 |
| B | FE701 |
| B | DZ4705 |
| B | HOH822 |
| B | HOH849 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 703 |
| Chain | Residue |
| B | DZ4705 |
| B | HOH829 |
| B | HOH842 |
| B | HOH848 |
| B | HOH877 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 704 |
| Chain | Residue |
| B | GTP706 |
| B | HOH818 |
| D | DZ4701 |
| site_id | AD3 |
| Number of Residues | 28 |
| Details | binding site for residue DZ4 B 705 |
| Chain | Residue |
| B | GLN149 |
| B | LEU150 |
| B | ARG164 |
| B | HIS167 |
| B | ASP207 |
| B | HIS210 |
| B | ALA215 |
| B | HIS233 |
| B | ASP311 |
| B | LYS312 |
| B | TYR315 |
| B | ASP319 |
| B | ARG366 |
| B | TYR374 |
| B | GLN375 |
| B | FE701 |
| B | MG702 |
| B | MG703 |
| B | HOH816 |
| B | HOH822 |
| B | HOH829 |
| B | HOH837 |
| B | HOH840 |
| B | HOH842 |
| B | HOH848 |
| B | HOH849 |
| B | HOH877 |
| B | HOH894 |
| site_id | AD4 |
| Number of Residues | 15 |
| Details | binding site for residue GTP B 706 |
| Chain | Residue |
| A | TYR155 |
| A | VAL156 |
| A | ARG451 |
| A | LYS455 |
| B | LYS116 |
| B | VAL117 |
| B | ILE118 |
| B | ASP137 |
| B | GLN142 |
| B | ARG145 |
| B | PHE165 |
| B | MG704 |
| B | HOH818 |
| D | LYS523 |
| D | DZ4701 |
| site_id | AD5 |
| Number of Residues | 18 |
| Details | binding site for residue DZ4 C 701 |
| Chain | Residue |
| A | VAL117 |
| A | ASN119 |
| A | MG704 |
| A | GTP706 |
| A | HOH823 |
| B | VAL156 |
| B | PHE157 |
| B | ARG372 |
| B | HIS376 |
| B | LYS377 |
| C | ARG333 |
| C | ARG352 |
| C | LYS354 |
| C | ASN358 |
| C | LYS523 |
| C | HOH807 |
| C | HOH856 |
| C | HOH872 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue FE C 702 |
| Chain | Residue |
| C | HIS167 |
| C | HIS206 |
| C | ASP207 |
| C | ASP311 |
| C | MG703 |
| C | DZ4706 |
| C | HOH825 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue MG C 703 |
| Chain | Residue |
| C | ASP207 |
| C | HIS233 |
| C | FE702 |
| C | DZ4706 |
| C | HOH825 |
| C | HOH832 |
| C | HOH841 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 704 |
| Chain | Residue |
| C | DZ4706 |
| C | HOH808 |
| C | HOH826 |
| C | HOH860 |
| C | HOH878 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue MG C 705 |
| Chain | Residue |
| A | DZ4707 |
| A | HOH811 |
| C | GTP707 |
| site_id | AE1 |
| Number of Residues | 29 |
| Details | binding site for residue DZ4 C 706 |
| Chain | Residue |
| C | GLN149 |
| C | LEU150 |
| C | ARG164 |
| C | HIS167 |
| C | ASP207 |
| C | HIS210 |
| C | ALA215 |
| C | HIS233 |
| C | ASP311 |
| C | LYS312 |
| C | TYR315 |
| C | ASP319 |
| C | ARG366 |
| C | TYR374 |
| C | FE702 |
| C | MG703 |
| C | MG704 |
| C | HOH808 |
| C | HOH809 |
| C | HOH813 |
| C | HOH819 |
| C | HOH825 |
| C | HOH826 |
| C | HOH832 |
| C | HOH851 |
| C | HOH860 |
| C | HOH878 |
| C | HOH885 |
| C | HOH904 |
| site_id | AE2 |
| Number of Residues | 16 |
| Details | binding site for residue GTP C 707 |
| Chain | Residue |
| A | LYS523 |
| A | DZ4707 |
| A | HOH811 |
| C | LYS116 |
| C | VAL117 |
| C | ILE118 |
| C | ASP137 |
| C | GLN142 |
| C | ARG145 |
| C | PHE165 |
| C | MG705 |
| D | TYR155 |
| D | VAL156 |
| D | VAL378 |
| D | ARG451 |
| D | LYS455 |
| site_id | AE3 |
| Number of Residues | 17 |
| Details | binding site for residue DZ4 C 708 |
| Chain | Residue |
| B | ARG333 |
| B | ARG352 |
| B | LYS354 |
| B | ASN358 |
| B | LYS523 |
| C | VAL156 |
| C | PHE157 |
| C | ARG372 |
| C | HIS376 |
| C | LYS377 |
| C | HOH835 |
| C | HOH893 |
| D | VAL117 |
| D | ASN119 |
| D | MG705 |
| D | GTP707 |
| D | HOH812 |
| site_id | AE4 |
| Number of Residues | 17 |
| Details | binding site for residue DZ4 D 701 |
| Chain | Residue |
| A | VAL156 |
| A | PHE157 |
| A | ARG372 |
| A | HIS376 |
| A | LYS377 |
| B | VAL117 |
| B | ASN119 |
| B | MG704 |
| B | GTP706 |
| B | HOH818 |
| D | ARG333 |
| D | ARG352 |
| D | LYS354 |
| D | ASN358 |
| D | LYS523 |
| D | HOH842 |
| D | HOH855 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue FE D 702 |
| Chain | Residue |
| D | HIS167 |
| D | HIS206 |
| D | ASP207 |
| D | ASP311 |
| D | DZ4706 |
| D | HOH847 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue MG D 703 |
| Chain | Residue |
| D | ASP207 |
| D | HIS233 |
| D | DZ4706 |
| D | HOH822 |
| D | HOH840 |
| D | HOH847 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for residue MG D 704 |
| Chain | Residue |
| D | DZ4706 |
| D | HOH809 |
| D | HOH830 |
| D | HOH841 |
| D | HOH872 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue MG D 705 |
| Chain | Residue |
| C | DZ4708 |
| D | LYS116 |
| D | GTP707 |
| D | HOH812 |
| site_id | AE9 |
| Number of Residues | 28 |
| Details | binding site for residue DZ4 D 706 |
| Chain | Residue |
| D | GLN149 |
| D | LEU150 |
| D | ARG164 |
| D | HIS167 |
| D | ASP207 |
| D | HIS210 |
| D | ALA215 |
| D | HIS233 |
| D | ASP311 |
| D | LYS312 |
| D | TYR315 |
| D | ASP319 |
| D | ARG366 |
| D | TYR374 |
| D | GLN375 |
| D | FE702 |
| D | MG703 |
| D | MG704 |
| D | HOH809 |
| D | HOH822 |
| D | HOH824 |
| D | HOH829 |
| D | HOH830 |
| D | HOH833 |
| D | HOH841 |
| D | HOH847 |
| D | HOH870 |
| D | HOH872 |
| site_id | AF1 |
| Number of Residues | 16 |
| Details | binding site for residue GTP D 707 |
| Chain | Residue |
| B | LYS523 |
| C | TYR155 |
| C | VAL156 |
| C | VAL378 |
| C | ARG451 |
| C | LYS455 |
| C | DZ4708 |
| D | LYS116 |
| D | VAL117 |
| D | ILE118 |
| D | ASP137 |
| D | GLN142 |
| D | ARG145 |
| D | PHE165 |
| D | MG705 |
| D | HOH812 |
| site_id | AF2 |
| Number of Residues | 4 |
| Details | binding site for residue MG D 708 |
| Chain | Residue |
| D | ASN504 |
| D | HOH802 |
| D | HOH894 |
| D | HOH897 |
| site_id | AF3 |
| Number of Residues | 7 |
| Details | binding site for residue FE E 701 |
| Chain | Residue |
| E | HIS167 |
| E | HIS206 |
| E | ASP207 |
| E | ASP311 |
| E | MG702 |
| E | DZ4705 |
| E | HOH837 |
| site_id | AF4 |
| Number of Residues | 7 |
| Details | binding site for residue MG E 702 |
| Chain | Residue |
| E | ASP207 |
| E | HIS233 |
| E | FE701 |
| E | DZ4705 |
| E | HOH826 |
| E | HOH827 |
| E | HOH837 |
| site_id | AF5 |
| Number of Residues | 5 |
| Details | binding site for residue MG E 703 |
| Chain | Residue |
| E | DZ4705 |
| E | HOH809 |
| E | HOH822 |
| E | HOH847 |
| E | HOH852 |
| site_id | AF6 |
| Number of Residues | 3 |
| Details | binding site for residue MG E 704 |
| Chain | Residue |
| E | GTP706 |
| E | HOH811 |
| G | DZ4701 |
| site_id | AF7 |
| Number of Residues | 26 |
| Details | binding site for residue DZ4 E 705 |
| Chain | Residue |
| E | GLN149 |
| E | LEU150 |
| E | ARG164 |
| E | HIS167 |
| E | ASP207 |
| E | HIS210 |
| E | ALA215 |
| E | HIS233 |
| E | ASP311 |
| E | LYS312 |
| E | TYR315 |
| E | ASP319 |
| E | ARG366 |
| E | TYR374 |
| E | GLN375 |
| E | FE701 |
| E | MG702 |
| E | MG703 |
| E | HOH809 |
| E | HOH821 |
| E | HOH822 |
| E | HOH827 |
| E | HOH837 |
| E | HOH847 |
| E | HOH852 |
| E | HOH853 |
| site_id | AF8 |
| Number of Residues | 17 |
| Details | binding site for residue GTP E 706 |
| Chain | Residue |
| E | LYS116 |
| E | VAL117 |
| E | ILE118 |
| E | ASP137 |
| E | GLN142 |
| E | ARG145 |
| E | PHE165 |
| E | MG704 |
| E | HOH811 |
| E | HOH825 |
| F | TYR155 |
| F | VAL156 |
| F | VAL378 |
| F | ARG451 |
| F | LYS455 |
| G | LYS523 |
| G | DZ4701 |
| site_id | AF9 |
| Number of Residues | 16 |
| Details | binding site for residue GTP E 707 |
| Chain | Residue |
| E | TYR155 |
| E | VAL156 |
| E | VAL378 |
| E | ARG451 |
| E | LYS455 |
| F | LYS116 |
| F | VAL117 |
| F | ILE118 |
| F | ASP137 |
| F | GLN142 |
| F | ARG145 |
| F | PHE165 |
| F | MG704 |
| H | LYS523 |
| H | DZ4701 |
| H | HOH812 |
| site_id | AG1 |
| Number of Residues | 15 |
| Details | binding site for residue DZ4 E 708 |
| Chain | Residue |
| E | ARG333 |
| E | ARG352 |
| E | LYS354 |
| E | ASN358 |
| E | LYS523 |
| G | VAL117 |
| G | ASN119 |
| G | MG705 |
| G | GTP707 |
| G | HOH826 |
| H | VAL156 |
| H | PHE157 |
| H | ARG372 |
| H | HIS376 |
| H | LYS377 |
| site_id | AG2 |
| Number of Residues | 7 |
| Details | binding site for residue FE F 701 |
| Chain | Residue |
| F | HIS167 |
| F | HIS206 |
| F | ASP207 |
| F | ASP311 |
| F | MG702 |
| F | DZ4705 |
| F | HOH869 |
| site_id | AG3 |
| Number of Residues | 7 |
| Details | binding site for residue MG F 702 |
| Chain | Residue |
| F | ASP207 |
| F | HIS233 |
| F | FE701 |
| F | DZ4705 |
| F | HOH843 |
| F | HOH859 |
| F | HOH869 |
| site_id | AG4 |
| Number of Residues | 5 |
| Details | binding site for residue MG F 703 |
| Chain | Residue |
| F | DZ4705 |
| F | HOH824 |
| F | HOH855 |
| F | HOH864 |
| F | HOH866 |
| site_id | AG5 |
| Number of Residues | 4 |
| Details | binding site for residue MG F 704 |
| Chain | Residue |
| E | GTP707 |
| F | LYS116 |
| H | DZ4701 |
| H | HOH812 |
| site_id | AG6 |
| Number of Residues | 30 |
| Details | binding site for residue DZ4 F 705 |
| Chain | Residue |
| F | GLN149 |
| F | LEU150 |
| F | ARG164 |
| F | HIS167 |
| F | ASP207 |
| F | HIS210 |
| F | ALA215 |
| F | HIS233 |
| F | ASP311 |
| F | LYS312 |
| F | TYR315 |
| F | ASP319 |
| F | ARG366 |
| F | TYR374 |
| F | GLN375 |
| F | FE701 |
| F | MG702 |
| F | MG703 |
| F | HOH812 |
| F | HOH824 |
| F | HOH825 |
| F | HOH837 |
| F | HOH855 |
| F | HOH859 |
| F | HOH864 |
| F | HOH866 |
| F | HOH869 |
| F | HOH871 |
| F | HOH881 |
| F | HOH901 |
| site_id | AG7 |
| Number of Residues | 17 |
| Details | binding site for residue DZ4 F 706 |
| Chain | Residue |
| F | ARG333 |
| F | ARG352 |
| F | LYS354 |
| F | ASN358 |
| F | LYS523 |
| F | HOH820 |
| F | HOH845 |
| F | HOH878 |
| G | VAL156 |
| G | PHE157 |
| G | ARG372 |
| G | HIS376 |
| G | LYS377 |
| H | VAL117 |
| H | ASN119 |
| H | MG705 |
| H | GTP707 |
| site_id | AG8 |
| Number of Residues | 17 |
| Details | binding site for residue DZ4 G 701 |
| Chain | Residue |
| E | VAL117 |
| E | ASN119 |
| E | MG704 |
| E | GTP706 |
| E | HOH811 |
| F | VAL156 |
| F | PHE157 |
| F | ARG372 |
| F | HIS376 |
| F | LYS377 |
| G | ARG333 |
| G | ARG352 |
| G | LYS354 |
| G | ASN358 |
| G | LYS523 |
| G | HOH872 |
| G | HOH879 |
| site_id | AG9 |
| Number of Residues | 7 |
| Details | binding site for residue FE G 702 |
| Chain | Residue |
| G | HIS167 |
| G | HIS206 |
| G | ASP207 |
| G | ASP311 |
| G | MG703 |
| G | DZ4706 |
| G | HOH847 |
| site_id | AH1 |
| Number of Residues | 7 |
| Details | binding site for residue MG G 703 |
| Chain | Residue |
| G | ASP207 |
| G | HIS233 |
| G | FE702 |
| G | DZ4706 |
| G | HOH847 |
| G | HOH862 |
| G | HOH866 |
| site_id | AH2 |
| Number of Residues | 5 |
| Details | binding site for residue MG G 704 |
| Chain | Residue |
| G | DZ4706 |
| G | HOH808 |
| G | HOH827 |
| G | HOH855 |
| G | HOH885 |
| site_id | AH3 |
| Number of Residues | 4 |
| Details | binding site for residue MG G 705 |
| Chain | Residue |
| E | DZ4708 |
| G | LYS116 |
| G | GTP707 |
| G | HOH826 |
| site_id | AH4 |
| Number of Residues | 29 |
| Details | binding site for residue DZ4 G 706 |
| Chain | Residue |
| G | GLN149 |
| G | LEU150 |
| G | ARG164 |
| G | HIS167 |
| G | ASP207 |
| G | HIS210 |
| G | ALA215 |
| G | HIS233 |
| G | ASP311 |
| G | LYS312 |
| G | TYR315 |
| G | ASP319 |
| G | ARG366 |
| G | TYR374 |
| G | GLN375 |
| G | FE702 |
| G | MG703 |
| G | MG704 |
| G | HOH803 |
| G | HOH808 |
| G | HOH827 |
| G | HOH836 |
| G | HOH847 |
| G | HOH850 |
| G | HOH852 |
| G | HOH855 |
| G | HOH862 |
| G | HOH874 |
| G | HOH885 |
| site_id | AH5 |
| Number of Residues | 16 |
| Details | binding site for residue GTP G 707 |
| Chain | Residue |
| E | LYS523 |
| E | DZ4708 |
| G | LYS116 |
| G | VAL117 |
| G | ILE118 |
| G | ASP137 |
| G | GLN142 |
| G | ARG145 |
| G | PHE165 |
| G | MG705 |
| G | HOH826 |
| H | TYR155 |
| H | VAL156 |
| H | VAL378 |
| H | ARG451 |
| H | LYS455 |
| site_id | AH6 |
| Number of Residues | 16 |
| Details | binding site for residue DZ4 H 701 |
| Chain | Residue |
| E | VAL156 |
| E | PHE157 |
| E | ARG372 |
| E | HIS376 |
| E | LYS377 |
| E | GTP707 |
| E | HOH841 |
| F | VAL117 |
| F | ASN119 |
| F | MG704 |
| H | ARG333 |
| H | ARG352 |
| H | LYS354 |
| H | ASN358 |
| H | LYS523 |
| H | HOH812 |
| site_id | AH7 |
| Number of Residues | 7 |
| Details | binding site for residue FE H 702 |
| Chain | Residue |
| H | HIS167 |
| H | HIS206 |
| H | ASP207 |
| H | ASP311 |
| H | MG703 |
| H | DZ4706 |
| H | HOH845 |
| site_id | AH8 |
| Number of Residues | 7 |
| Details | binding site for residue MG H 703 |
| Chain | Residue |
| H | ASP207 |
| H | HIS233 |
| H | FE702 |
| H | DZ4706 |
| H | HOH833 |
| H | HOH835 |
| H | HOH845 |
| site_id | AH9 |
| Number of Residues | 5 |
| Details | binding site for residue MG H 704 |
| Chain | Residue |
| H | DZ4706 |
| H | HOH804 |
| H | HOH808 |
| H | HOH817 |
| H | HOH826 |
| site_id | AI1 |
| Number of Residues | 3 |
| Details | binding site for residue MG H 705 |
| Chain | Residue |
| F | DZ4706 |
| F | HOH878 |
| H | GTP707 |
| site_id | AI2 |
| Number of Residues | 28 |
| Details | binding site for residue DZ4 H 706 |
| Chain | Residue |
| H | GLN149 |
| H | LEU150 |
| H | ARG164 |
| H | HIS167 |
| H | ASP207 |
| H | HIS210 |
| H | ALA215 |
| H | HIS233 |
| H | ASP311 |
| H | LYS312 |
| H | TYR315 |
| H | ASP319 |
| H | ARG366 |
| H | TYR374 |
| H | GLN375 |
| H | FE702 |
| H | MG703 |
| H | MG704 |
| H | HOH804 |
| H | HOH806 |
| H | HOH807 |
| H | HOH808 |
| H | HOH821 |
| H | HOH825 |
| H | HOH826 |
| H | HOH835 |
| H | HOH843 |
| H | HOH845 |
| site_id | AI3 |
| Number of Residues | 16 |
| Details | binding site for residue GTP H 707 |
| Chain | Residue |
| F | LYS523 |
| F | DZ4706 |
| F | HOH878 |
| G | TYR155 |
| G | VAL156 |
| G | VAL378 |
| G | ARG451 |
| G | LYS455 |
| H | LYS116 |
| H | VAL117 |
| H | ILE118 |
| H | ASP137 |
| H | GLN142 |
| H | ARG145 |
| H | PHE165 |
| H | MG705 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"22056990","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 40 |
| Details | Binding site: {"description":"in chain B","evidences":[{"source":"PubMed","id":"25267621","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4TNP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4TNQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4TNR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4TNX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"description":"in chain B","evidences":[{"source":"PubMed","id":"25267621","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4TNQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 64 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25267621","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4TNQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 56 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24141705","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4BZB","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 32 |
| Details | Binding site: {"description":"in chain C","evidences":[{"source":"PubMed","id":"25267621","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4TNQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 24 |
| Details | Binding site: {"description":"in chain A","evidences":[{"source":"PubMed","id":"25267621","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4TNQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 8 |
| Details | Binding site: {"description":"in chain A","evidences":[{"source":"PubMed","id":"24141705","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25267621","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4BZB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4TNX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 16 |
| Details | Binding site: {"description":"in chain C","evidences":[{"source":"PubMed","id":"25267621","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4TNP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4TNQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4TNR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4TNX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 8 |
| Details | Binding site: {"description":"in chain A","evidences":[{"source":"PubMed","id":"25267621","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4TNP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4TNQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4TNR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4TNX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 7 |
| Details | Modified residue: {"description":"Phosphothreonine; by CDK1","evidences":[{"source":"PubMed","id":"23601106","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23602554","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26294762","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26431200","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29610582","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29670289","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17081983","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 32 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
