6XLI
CRYSTAL STRUCTURE OF ANTI-TAU ANTIBODY PT3 Fab+pT212/pT217-TAU PEPTIDE
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 301 |
| Chain | Residue |
| A | PHE171 |
| B | THR178 |
| A | PRO172 |
| A | VAL174 |
| A | SER182 |
| A | LEU183 |
| A | SER184 |
| B | GLN160 |
| B | SER176 |
| B | SER177 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue GOL D 301 |
| Chain | Residue |
| C | PHE171 |
| C | PRO172 |
| C | SER182 |
| C | LEU183 |
| C | SER184 |
| D | SER162 |
| D | SER176 |
| D | THR178 |
| D | HOH402 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue GOL L 301 |
| Chain | Residue |
| H | PHE171 |
| H | PRO172 |
| H | VAL174 |
| H | SER182 |
| H | LEU183 |
| H | SER184 |
| L | SER162 |
| L | SER176 |
| L | SER177 |
| L | THR178 |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| A | TYR199-HIS205 | |
| B | TYR192-HIS198 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphothreonine; by BRSK1, BRSK2, DYRK2 and PDPK1 => ECO:0000269|PubMed:15546861, ECO:0000269|PubMed:18599021, ECO:0000269|PubMed:19451179, ECO:0000269|PubMed:21985311, ECO:0000269|PubMed:9614189 |
| Chain | Residue | Details |
| E | TPO212 | |
| F | TPO212 | |
| P | TPO212 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphoserine; by PKA => ECO:0000269|PubMed:15546861, ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:19451179, ECO:0000269|PubMed:9614189 |
| Chain | Residue | Details |
| E | SER214 | |
| F | SER214 | |
| P | SER214 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphothreonine; by PDPK1 => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:19451179 |
| Chain | Residue | Details |
| E | TPO217 | |
| F | TPO217 | |
| P | TPO217 |
