6XG3
The crystal structure of Papain-Like Protease of SARS CoV-2 , C111S mutant, at room temperature
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 501 |
| Chain | Residue |
| A | CYS189 |
| A | CYS192 |
| A | CYS224 |
| A | CYS226 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue PO4 A 502 |
| Chain | Residue |
| A | GLY271 |
| A | HIS272 |
| A | TRP106 |
| A | ASN109 |
| A | ASN110 |
| A | SER111 |
| A | LYS228 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CL A 503 |
| Chain | Residue |
| A | THR10 |
| A | VAL11 |
| A | ASP12 |
| A | ASN15 |
| A | HIS17 |
| A | GLU67 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 37 |
| Details | ZN_FING: C4-type => ECO:0000255|PROSITE-ProRule:PRU00444 |
| Chain | Residue | Details |
| A | CYS189-CYS226 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: For PL-PRO activity => ECO:0000255|PROSITE-ProRule:PRU00444, ECO:0000269|PubMed:32726803 |
| Chain | Residue | Details |
| A | SER111 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | ACT_SITE: For PL-PRO activity => ECO:0000255|PROSITE-ProRule:PRU00444 |
| Chain | Residue | Details |
| A | HIS272 | |
| A | ASP286 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00444 |
| Chain | Residue | Details |
| A | CYS189 | |
| A | CYS192 | |
| A | CYS224 | |
| A | CYS226 |
