Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue V1Y A 801 |
| Chain | Residue |
| A | ALA481 |
| A | CYS532 |
| A | GLY593 |
| A | ASP594 |
| A | HOH916 |
| A | HOH950 |
| A | LYS483 |
| A | GLU501 |
| A | LEU505 |
| A | LEU514 |
| A | ILE527 |
| A | THR529 |
| A | GLN530 |
| A | TRP531 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 803 |
| Chain | Residue |
| A | HIS608 |
| A | HOH909 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 804 |
| Chain | Residue |
| A | TRP450 |
| A | TRP450 |
| A | ARG509 |
| A | ARG509 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 805 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 806 |
| Chain | Residue |
| A | GLY478 |
| A | LEU711 |
| A | GLU715 |
| A | HOH970 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 21 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGSGSFGTVYkGkwhgd.............VAVK |
| Chain | Residue | Details |
| A | ILE463-LYS483 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IiHrDLKsnNIFL |
| Chain | Residue | Details |
| A | ILE572-LEU584 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 260 |
| Details | Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Omega-N-methylarginine; by PRMT5","evidences":[{"source":"PubMed","id":"21917714","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"23907581","evidenceCode":"ECO:0000269"}]} |
