6XBB
Crystal structure of Streptomyces sviceus SsDesB in complex with NADP+
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0047091 | molecular_function | L-lysine 6-monooxygenase (NADPH) activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0047091 | molecular_function | L-lysine 6-monooxygenase (NADPH) activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0047091 | molecular_function | L-lysine 6-monooxygenase (NADPH) activity |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0047091 | molecular_function | L-lysine 6-monooxygenase (NADPH) activity |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0047091 | molecular_function | L-lysine 6-monooxygenase (NADPH) activity |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0047091 | molecular_function | L-lysine 6-monooxygenase (NADPH) activity |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0047091 | molecular_function | L-lysine 6-monooxygenase (NADPH) activity |
| H | 0000166 | molecular_function | nucleotide binding |
| H | 0047091 | molecular_function | L-lysine 6-monooxygenase (NADPH) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 36 |
| Details | binding site for residue FAD A 501 |
| Chain | Residue |
| A | GLY18 |
| A | TRP49 |
| A | HIS50 |
| A | LEU60 |
| A | GLN61 |
| A | THR62 |
| A | THR124 |
| A | VAL126 |
| A | GLY154 |
| A | THR155 |
| A | GLY156 |
| A | LEU19 |
| A | TYR337 |
| A | PHE344 |
| A | ASN379 |
| A | PRO390 |
| A | ASP391 |
| A | LEU392 |
| A | NAP502 |
| A | HOH601 |
| A | HOH647 |
| A | HOH659 |
| A | GLY20 |
| A | HOH674 |
| A | HOH682 |
| A | HOH691 |
| A | HOH720 |
| A | HOH749 |
| A | HOH765 |
| G | ASN308 |
| A | PRO21 |
| A | PHE22 |
| A | LEU41 |
| A | GLU42 |
| A | SER43 |
| A | LYS44 |
| site_id | AC2 |
| Number of Residues | 31 |
| Details | binding site for residue NAP A 502 |
| Chain | Residue |
| A | HIS59 |
| A | LEU60 |
| A | GLN61 |
| A | ARG103 |
| A | PRO162 |
| A | VAL194 |
| A | GLY195 |
| A | SER196 |
| A | GLY197 |
| A | GLN198 |
| A | SER199 |
| A | GLU202 |
| A | THR222 |
| A | ARG223 |
| A | SER224 |
| A | LYS264 |
| A | PHE267 |
| A | LYS268 |
| A | LEU301 |
| A | ALA334 |
| A | THR335 |
| A | GLY336 |
| A | TYR337 |
| A | FAD501 |
| A | HOH602 |
| A | HOH633 |
| A | HOH678 |
| A | HOH680 |
| A | HOH698 |
| A | HOH701 |
| A | HOH725 |
| site_id | AC3 |
| Number of Residues | 32 |
| Details | binding site for residue FAD B 501 |
| Chain | Residue |
| B | GLY18 |
| B | GLY20 |
| B | PRO21 |
| B | PHE22 |
| B | LEU41 |
| B | GLU42 |
| B | SER43 |
| B | LYS44 |
| B | TRP49 |
| B | HIS50 |
| B | LEU60 |
| B | GLN61 |
| B | THR62 |
| B | THR124 |
| B | VAL126 |
| B | GLY154 |
| B | THR155 |
| B | GLY156 |
| B | TYR337 |
| B | PHE344 |
| B | ASN379 |
| B | PRO390 |
| B | ASP391 |
| B | LEU392 |
| B | NAP502 |
| B | HOH609 |
| B | HOH665 |
| B | HOH694 |
| B | HOH701 |
| B | HOH705 |
| B | HOH721 |
| B | HOH724 |
| site_id | AC4 |
| Number of Residues | 32 |
| Details | binding site for residue NAP B 502 |
| Chain | Residue |
| B | HIS59 |
| B | GLN61 |
| B | ARG103 |
| B | PRO162 |
| B | VAL194 |
| B | GLY195 |
| B | SER196 |
| B | GLY197 |
| B | GLN198 |
| B | SER199 |
| B | GLU202 |
| B | THR222 |
| B | ARG223 |
| B | SER224 |
| B | LYS264 |
| B | PHE267 |
| B | LYS268 |
| B | SER299 |
| B | LEU301 |
| B | ALA334 |
| B | THR335 |
| B | GLY336 |
| B | TYR337 |
| B | FAD501 |
| B | HOH603 |
| B | HOH669 |
| B | HOH690 |
| B | HOH691 |
| B | HOH733 |
| B | HOH738 |
| B | HOH744 |
| B | HOH745 |
| site_id | AC5 |
| Number of Residues | 30 |
| Details | binding site for residue FAD C 501 |
| Chain | Residue |
| C | GLY18 |
| C | LEU19 |
| C | GLY20 |
| C | PRO21 |
| C | PHE22 |
| C | LEU41 |
| C | GLU42 |
| C | SER43 |
| C | TRP49 |
| C | HIS50 |
| C | LEU60 |
| C | GLN61 |
| C | THR62 |
| C | THR124 |
| C | VAL126 |
| C | GLY154 |
| C | THR155 |
| C | GLY156 |
| C | TYR337 |
| C | PHE344 |
| C | ASN379 |
| C | PRO390 |
| C | ASP391 |
| C | LEU392 |
| C | NAP502 |
| C | HOH609 |
| C | HOH683 |
| C | HOH689 |
| C | HOH694 |
| C | HOH739 |
| site_id | AC6 |
| Number of Residues | 28 |
| Details | binding site for residue NAP C 502 |
| Chain | Residue |
| C | HIS59 |
| C | GLN61 |
| C | ARG103 |
| C | PRO162 |
| C | VAL194 |
| C | GLY195 |
| C | SER196 |
| C | GLY197 |
| C | GLN198 |
| C | SER199 |
| C | THR222 |
| C | ARG223 |
| C | SER224 |
| C | LYS264 |
| C | PHE267 |
| C | LYS268 |
| C | SER299 |
| C | LEU301 |
| C | ALA334 |
| C | THR335 |
| C | GLY336 |
| C | TYR337 |
| C | FAD501 |
| C | HOH606 |
| C | HOH617 |
| C | HOH648 |
| C | HOH703 |
| C | HOH706 |
| site_id | AC7 |
| Number of Residues | 30 |
| Details | binding site for residue FAD D 501 |
| Chain | Residue |
| D | GLY18 |
| D | LEU19 |
| D | GLY20 |
| D | PRO21 |
| D | PHE22 |
| D | LEU41 |
| D | GLU42 |
| D | SER43 |
| D | LYS44 |
| D | TRP49 |
| D | HIS50 |
| D | LEU60 |
| D | GLN61 |
| D | THR62 |
| D | THR124 |
| D | THR125 |
| D | VAL126 |
| D | GLY154 |
| D | THR155 |
| D | GLY156 |
| D | TYR337 |
| D | PHE344 |
| D | ASN379 |
| D | PRO390 |
| D | ASP391 |
| D | LEU392 |
| D | NAP502 |
| D | HOH632 |
| D | HOH639 |
| D | HOH649 |
| site_id | AC8 |
| Number of Residues | 29 |
| Details | binding site for residue NAP D 502 |
| Chain | Residue |
| D | HIS59 |
| D | LEU60 |
| D | GLN61 |
| D | ARG103 |
| D | PRO162 |
| D | VAL194 |
| D | GLY195 |
| D | SER196 |
| D | GLY197 |
| D | GLN198 |
| D | SER199 |
| D | THR222 |
| D | ARG223 |
| D | SER224 |
| D | LYS264 |
| D | PHE267 |
| D | LYS268 |
| D | SER299 |
| D | LEU301 |
| D | ALA334 |
| D | THR335 |
| D | GLY336 |
| D | TYR337 |
| D | FAD501 |
| D | HOH610 |
| D | HOH635 |
| D | HOH646 |
| D | HOH661 |
| D | HOH716 |
| site_id | AC9 |
| Number of Residues | 32 |
| Details | binding site for residue FAD E 501 |
| Chain | Residue |
| C | ASN308 |
| E | GLY18 |
| E | LEU19 |
| E | GLY20 |
| E | PRO21 |
| E | PHE22 |
| E | LEU41 |
| E | GLU42 |
| E | SER43 |
| E | LYS44 |
| E | TRP49 |
| E | HIS50 |
| E | LEU60 |
| E | GLN61 |
| E | THR62 |
| E | THR124 |
| E | VAL126 |
| E | GLY154 |
| E | THR155 |
| E | GLY156 |
| E | TYR337 |
| E | PHE344 |
| E | ASN379 |
| E | PRO390 |
| E | ASP391 |
| E | LEU392 |
| E | NAP502 |
| E | HOH602 |
| E | HOH615 |
| E | HOH621 |
| E | HOH644 |
| E | HOH698 |
| site_id | AD1 |
| Number of Residues | 27 |
| Details | binding site for residue NAP E 502 |
| Chain | Residue |
| E | HIS59 |
| E | LEU60 |
| E | GLN61 |
| E | ARG103 |
| E | VAL194 |
| E | GLY195 |
| E | SER196 |
| E | GLY197 |
| E | GLN198 |
| E | SER199 |
| E | GLU202 |
| E | THR222 |
| E | ARG223 |
| E | SER224 |
| E | LYS264 |
| E | PHE267 |
| E | LYS268 |
| E | LEU301 |
| E | ALA334 |
| E | THR335 |
| E | GLY336 |
| E | TYR337 |
| E | FAD501 |
| E | HOH614 |
| E | HOH624 |
| E | HOH631 |
| E | HOH680 |
| site_id | AD2 |
| Number of Residues | 31 |
| Details | binding site for residue FAD F 501 |
| Chain | Residue |
| F | GLY18 |
| F | LEU19 |
| F | GLY20 |
| F | PRO21 |
| F | PHE22 |
| F | LEU41 |
| F | GLU42 |
| F | SER43 |
| F | LYS44 |
| F | TRP49 |
| F | HIS50 |
| F | LEU60 |
| F | GLN61 |
| F | THR62 |
| F | THR124 |
| F | VAL126 |
| F | GLY154 |
| F | THR155 |
| F | GLY156 |
| F | TYR337 |
| F | PHE344 |
| F | ASN379 |
| F | PRO390 |
| F | ASP391 |
| F | LEU392 |
| F | NAP502 |
| F | HOH601 |
| F | HOH608 |
| F | HOH631 |
| F | HOH641 |
| F | HOH703 |
| site_id | AD3 |
| Number of Residues | 27 |
| Details | binding site for residue NAP F 502 |
| Chain | Residue |
| F | HIS59 |
| F | GLN61 |
| F | ARG103 |
| F | PRO162 |
| F | VAL194 |
| F | GLY195 |
| F | SER196 |
| F | GLY197 |
| F | GLN198 |
| F | SER199 |
| F | GLU202 |
| F | THR222 |
| F | ARG223 |
| F | SER224 |
| F | PHE267 |
| F | LYS268 |
| F | SER299 |
| F | LEU301 |
| F | ALA334 |
| F | THR335 |
| F | GLY336 |
| F | TYR337 |
| F | FAD501 |
| F | HOH602 |
| F | HOH629 |
| F | HOH681 |
| F | HOH686 |
| site_id | AD4 |
| Number of Residues | 31 |
| Details | binding site for residue FAD G 501 |
| Chain | Residue |
| G | GLY18 |
| G | LEU19 |
| G | GLY20 |
| G | PRO21 |
| G | PHE22 |
| G | LEU41 |
| G | GLU42 |
| G | SER43 |
| G | LYS44 |
| G | TRP49 |
| G | HIS50 |
| G | LEU60 |
| G | GLN61 |
| G | THR62 |
| G | THR124 |
| G | VAL126 |
| G | GLY154 |
| G | THR155 |
| G | GLY156 |
| G | TYR337 |
| G | PHE344 |
| G | ASN379 |
| G | PRO390 |
| G | ASP391 |
| G | LEU392 |
| G | NAP502 |
| G | HOH620 |
| G | HOH627 |
| G | HOH650 |
| G | HOH667 |
| G | HOH678 |
| site_id | AD5 |
| Number of Residues | 26 |
| Details | binding site for residue NAP G 502 |
| Chain | Residue |
| G | HIS59 |
| G | GLN61 |
| G | ARG103 |
| G | VAL194 |
| G | GLY195 |
| G | SER196 |
| G | GLY197 |
| G | GLN198 |
| G | SER199 |
| G | GLU202 |
| G | THR222 |
| G | ARG223 |
| G | SER224 |
| G | LYS264 |
| G | PHE267 |
| G | LYS268 |
| G | LEU301 |
| G | ALA334 |
| G | THR335 |
| G | GLY336 |
| G | TYR337 |
| G | FAD501 |
| G | HOH605 |
| G | HOH611 |
| G | HOH651 |
| G | HOH664 |
| site_id | AD6 |
| Number of Residues | 30 |
| Details | binding site for residue FAD H 501 |
| Chain | Residue |
| H | GLY18 |
| H | GLY20 |
| H | PRO21 |
| H | PHE22 |
| H | LEU41 |
| H | GLU42 |
| H | SER43 |
| H | LYS44 |
| H | TRP49 |
| H | HIS50 |
| H | LEU60 |
| H | GLN61 |
| H | THR62 |
| H | THR124 |
| H | VAL126 |
| H | GLY154 |
| H | THR155 |
| H | GLY156 |
| H | TYR337 |
| H | PHE344 |
| H | ASN379 |
| H | PRO390 |
| H | ASP391 |
| H | LEU392 |
| H | NAP502 |
| H | HOH633 |
| H | HOH634 |
| H | HOH635 |
| H | HOH647 |
| H | HOH703 |
| site_id | AD7 |
| Number of Residues | 27 |
| Details | binding site for residue NAP H 502 |
| Chain | Residue |
| H | HIS59 |
| H | GLN61 |
| H | ARG103 |
| H | PRO162 |
| H | VAL194 |
| H | GLY195 |
| H | SER196 |
| H | GLY197 |
| H | GLN198 |
| H | SER199 |
| H | GLU202 |
| H | THR222 |
| H | ARG223 |
| H | SER224 |
| H | PHE267 |
| H | LYS268 |
| H | LEU301 |
| H | ALA334 |
| H | THR335 |
| H | GLY336 |
| H | TYR337 |
| H | FAD501 |
| H | HOH605 |
| H | HOH637 |
| H | HOH651 |
| H | HOH660 |
| H | HOH688 |
