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6X88

PDE6 chicken GAF domain

Functional Information from GO Data
ChainGOidnamespacecontents
A0004114molecular_function3',5'-cyclic-nucleotide phosphodiesterase activity
A0004115molecular_function3',5'-cyclic-AMP phosphodiesterase activity
A0004117molecular_functioncalmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity
A0005886cellular_componentplasma membrane
A0007165biological_processsignal transduction
A0007601biological_processvisual perception
A0008081molecular_functionphosphoric diester hydrolase activity
A0016787molecular_functionhydrolase activity
A0019933biological_processcAMP-mediated signaling
A0030553molecular_functioncGMP binding
A0046872molecular_functionmetal ion binding
A0047555molecular_function3',5'-cyclic-GMP phosphodiesterase activity
A0048101molecular_functioncalmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity
B0004114molecular_function3',5'-cyclic-nucleotide phosphodiesterase activity
B0004115molecular_function3',5'-cyclic-AMP phosphodiesterase activity
B0004117molecular_functioncalmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity
B0005886cellular_componentplasma membrane
B0007165biological_processsignal transduction
B0007601biological_processvisual perception
B0008081molecular_functionphosphoric diester hydrolase activity
B0016787molecular_functionhydrolase activity
B0019933biological_processcAMP-mediated signaling
B0030553molecular_functioncGMP binding
B0046872molecular_functionmetal ion binding
B0047555molecular_function3',5'-cyclic-GMP phosphodiesterase activity
B0048101molecular_functioncalmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity
Functional Information from PROSITE/UniProt
site_idPS00126
Number of Residues12
DetailsPDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDIdHrGtnNlY
ChainResidueDetails
AHIS602-TYR613

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: Proton donor => ECO:0000250
ChainResidueDetails
AHIS562
BHIS562

site_idSWS_FT_FI2
Number of Residues8
DetailsBINDING: BINDING => ECO:0000269|PubMed:18614542
ChainResidueDetails
ASER97
AASN116
AASP169
ATHR176
BSER97
BASN116
BASP169
BTHR176

site_idSWS_FT_FI3
Number of Residues8
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
AHIS566
AHIS602
AASP603
AASP723
BHIS566
BHIS602
BASP603
BASP723

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: Cysteine methyl ester => ECO:0000255
ChainResidueDetails
ACYS859
BCYS859

site_idSWS_FT_FI5
Number of Residues2
DetailsLIPID: S-geranylgeranyl cysteine => ECO:0000250
ChainResidueDetails
ACYS859
BCYS859

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PDB entries from 2024-11-06

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