6X7A

Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor SGT572

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0005576	cellular_component	extracellular region
AAA	0005829	cellular_component	cytosol
AAA	0008080	molecular_function	N-acetyltransferase activity
AAA	0016740	molecular_function	transferase activity
AAA	0016746	molecular_function	acyltransferase activity
AAA	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
AAA	0030649	biological_process	aminoglycoside antibiotic catabolic process
AAA	0033661	biological_process	effector-mediated defense to host-produced reactive oxygen species
AAA	0034069	molecular_function	aminoglycoside N-acetyltransferase activity
AAA	0042802	molecular_function	identical protein binding
AAA	0043655	cellular_component	host extracellular space
AAA	0044161	cellular_component	host cell cytoplasmic vesicle
AAA	0046677	biological_process	response to antibiotic
AAA	0051701	biological_process	biological process involved in interaction with host
AAA	0052032	biological_process	symbiont-mediated perturbation of host inflammatory response
AAA	0052040	biological_process	symbiont-mediated perturbation of host programmed cell death
AAA	0052041	biological_process	symbiont-mediated suppression of host programmed cell death
AAA	0052167	biological_process	symbiont-mediated perturbation of host innate immune response
AAA	0061733	molecular_function	protein-lysine-acetyltransferase activity
AAA	0097691	cellular_component	bacterial extracellular vesicle

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"21628583","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton acceptor; via carboxylate","evidences":[{"source":"PubMed","id":"21628583","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22547814","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21628583","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3RYO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22547814","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21628583","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"24106131","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"27010218","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3RYO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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