6X0I
Structure of oxidized SidA ornithine hydroxylase with the FAD "in" and complexed with NADP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0004499 | molecular_function | N,N-dimethylaniline monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0006696 | biological_process | ergosterol biosynthetic process |
| A | 0006879 | biological_process | intracellular iron ion homeostasis |
| A | 0010106 | biological_process | cellular response to iron ion starvation |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019290 | biological_process | siderophore biosynthetic process |
| A | 0031169 | biological_process | ferrichrome biosynthetic process |
| A | 0031172 | molecular_function | ornithine N5-monooxygenase activity |
| A | 0033214 | biological_process | siderophore-iron import into cell |
| A | 0044550 | biological_process | secondary metabolite biosynthetic process |
| A | 0070401 | molecular_function | NADP+ binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0004499 | molecular_function | N,N-dimethylaniline monooxygenase activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0006696 | biological_process | ergosterol biosynthetic process |
| B | 0006879 | biological_process | intracellular iron ion homeostasis |
| B | 0010106 | biological_process | cellular response to iron ion starvation |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019290 | biological_process | siderophore biosynthetic process |
| B | 0031169 | biological_process | ferrichrome biosynthetic process |
| B | 0031172 | molecular_function | ornithine N5-monooxygenase activity |
| B | 0033214 | biological_process | siderophore-iron import into cell |
| B | 0044550 | biological_process | secondary metabolite biosynthetic process |
| B | 0070401 | molecular_function | NADP+ binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004497 | molecular_function | monooxygenase activity |
| C | 0004499 | molecular_function | N,N-dimethylaniline monooxygenase activity |
| C | 0005506 | molecular_function | iron ion binding |
| C | 0006696 | biological_process | ergosterol biosynthetic process |
| C | 0006879 | biological_process | intracellular iron ion homeostasis |
| C | 0010106 | biological_process | cellular response to iron ion starvation |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0019290 | biological_process | siderophore biosynthetic process |
| C | 0031169 | biological_process | ferrichrome biosynthetic process |
| C | 0031172 | molecular_function | ornithine N5-monooxygenase activity |
| C | 0033214 | biological_process | siderophore-iron import into cell |
| C | 0044550 | biological_process | secondary metabolite biosynthetic process |
| C | 0070401 | molecular_function | NADP+ binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004497 | molecular_function | monooxygenase activity |
| D | 0004499 | molecular_function | N,N-dimethylaniline monooxygenase activity |
| D | 0005506 | molecular_function | iron ion binding |
| D | 0006696 | biological_process | ergosterol biosynthetic process |
| D | 0006879 | biological_process | intracellular iron ion homeostasis |
| D | 0010106 | biological_process | cellular response to iron ion starvation |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0019290 | biological_process | siderophore biosynthetic process |
| D | 0031169 | biological_process | ferrichrome biosynthetic process |
| D | 0031172 | molecular_function | ornithine N5-monooxygenase activity |
| D | 0033214 | biological_process | siderophore-iron import into cell |
| D | 0044550 | biological_process | secondary metabolite biosynthetic process |
| D | 0070401 | molecular_function | NADP+ binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 601 |
| Chain | Residue |
| A | ILE103 |
| A | LYS107 |
| A | PHE296 |
| A | SER469 |
| site_id | AC2 |
| Number of Residues | 32 |
| Details | binding site for residue FAD A 602 |
| Chain | Residue |
| A | GLU83 |
| A | ARG84 |
| A | GLN85 |
| A | TRP90 |
| A | HIS91 |
| A | MET94 |
| A | MET101 |
| A | GLN102 |
| A | ILE103 |
| A | GLU166 |
| A | GLU167 |
| A | VAL168 |
| A | ALA209 |
| A | ILE210 |
| A | GLY211 |
| A | TYR407 |
| A | ARG409 |
| A | SER466 |
| A | LEU467 |
| A | LEU468 |
| A | NAP603 |
| A | HOH710 |
| A | HOH776 |
| A | HOH799 |
| A | HOH826 |
| A | HOH857 |
| A | HOH919 |
| A | GLY46 |
| A | GLY48 |
| A | PRO49 |
| A | ALA50 |
| A | LEU82 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | binding site for residue NAP A 603 |
| Chain | Residue |
| A | LYS100 |
| A | GLN102 |
| A | PRO217 |
| A | SER254 |
| A | GLY255 |
| A | GLN256 |
| A | SER257 |
| A | GLU260 |
| A | ARG279 |
| A | ASN323 |
| A | TYR324 |
| A | SER325 |
| A | ALA404 |
| A | THR405 |
| A | GLY406 |
| A | FAD602 |
| A | HOH706 |
| A | HOH778 |
| A | HOH782 |
| A | HOH783 |
| A | HOH851 |
| A | HOH865 |
| A | HOH879 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue CA A 604 |
| Chain | Residue |
| A | ASP288 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ACT B 601 |
| Chain | Residue |
| B | ILE103 |
| B | LYS107 |
| B | PHE296 |
| B | SER469 |
| site_id | AC6 |
| Number of Residues | 34 |
| Details | binding site for residue FAD B 602 |
| Chain | Residue |
| B | GLY46 |
| B | GLY48 |
| B | PRO49 |
| B | ALA50 |
| B | GLU83 |
| B | ARG84 |
| B | GLN85 |
| B | TRP90 |
| B | HIS91 |
| B | MET94 |
| B | MET101 |
| B | GLN102 |
| B | ILE103 |
| B | GLU166 |
| B | GLU167 |
| B | VAL168 |
| B | ALA209 |
| B | ILE210 |
| B | GLY211 |
| B | TYR407 |
| B | ARG409 |
| B | SER466 |
| B | LEU467 |
| B | LEU468 |
| B | NAP603 |
| B | HOH728 |
| B | HOH735 |
| B | HOH761 |
| B | HOH772 |
| B | HOH778 |
| B | HOH838 |
| B | HOH866 |
| B | HOH905 |
| B | HOH926 |
| site_id | AC7 |
| Number of Residues | 26 |
| Details | binding site for residue NAP B 603 |
| Chain | Residue |
| B | GLN102 |
| B | PRO217 |
| B | SER254 |
| B | GLY255 |
| B | GLN256 |
| B | SER257 |
| B | GLU260 |
| B | ARG279 |
| B | ASN323 |
| B | TYR324 |
| B | SER325 |
| B | ALA404 |
| B | THR405 |
| B | GLY406 |
| B | FAD602 |
| B | HOH711 |
| B | HOH724 |
| B | HOH748 |
| B | HOH766 |
| B | HOH770 |
| B | HOH815 |
| B | HOH851 |
| B | HOH863 |
| B | HOH945 |
| B | HOH955 |
| B | LYS100 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue CA B 604 |
| Chain | Residue |
| A | HOH771 |
| B | ASP288 |
| B | HOH912 |
| C | HOH774 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue ACT C 601 |
| Chain | Residue |
| C | ILE103 |
| C | LYS107 |
| C | ASN293 |
| C | PHE296 |
| C | SER469 |
| site_id | AD1 |
| Number of Residues | 36 |
| Details | binding site for residue FAD C 602 |
| Chain | Residue |
| C | GLY46 |
| C | GLY48 |
| C | PRO49 |
| C | ALA50 |
| C | LEU82 |
| C | GLU83 |
| C | ARG84 |
| C | GLN85 |
| C | TRP90 |
| C | HIS91 |
| C | MET94 |
| C | MET101 |
| C | GLN102 |
| C | ILE103 |
| C | ARG144 |
| C | GLU166 |
| C | GLU167 |
| C | VAL168 |
| C | ALA209 |
| C | ILE210 |
| C | GLY211 |
| C | TYR324 |
| C | TYR407 |
| C | ARG409 |
| C | SER466 |
| C | LEU467 |
| C | LEU468 |
| C | NAP603 |
| C | HOH731 |
| C | HOH735 |
| C | HOH775 |
| C | HOH808 |
| C | HOH811 |
| C | HOH831 |
| C | HOH864 |
| C | HOH873 |
| site_id | AD2 |
| Number of Residues | 24 |
| Details | binding site for residue NAP C 603 |
| Chain | Residue |
| C | LYS100 |
| C | GLN102 |
| C | PRO217 |
| C | SER254 |
| C | GLY255 |
| C | GLN256 |
| C | SER257 |
| C | GLU260 |
| C | ARG279 |
| C | ASN323 |
| C | TYR324 |
| C | SER325 |
| C | ALA404 |
| C | THR405 |
| C | GLY406 |
| C | FAD602 |
| C | HOH760 |
| C | HOH783 |
| C | HOH784 |
| C | HOH811 |
| C | HOH825 |
| C | HOH839 |
| C | HOH893 |
| C | HOH902 |
| site_id | AD3 |
| Number of Residues | 1 |
| Details | binding site for residue CA C 604 |
| Chain | Residue |
| C | ASP288 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue ACT D 601 |
| Chain | Residue |
| D | ILE103 |
| D | LYS107 |
| D | PHE296 |
| D | SER469 |
| D | HOH863 |
| site_id | AD5 |
| Number of Residues | 29 |
| Details | binding site for residue FAD D 602 |
| Chain | Residue |
| D | GLY46 |
| D | GLY48 |
| D | PRO49 |
| D | ALA50 |
| D | LEU82 |
| D | GLU83 |
| D | ARG84 |
| D | GLN85 |
| D | TRP90 |
| D | HIS91 |
| D | MET94 |
| D | MET101 |
| D | GLN102 |
| D | ILE103 |
| D | GLU166 |
| D | VAL168 |
| D | ALA209 |
| D | ILE210 |
| D | GLY211 |
| D | TYR407 |
| D | ARG409 |
| D | SER466 |
| D | LEU467 |
| D | LEU468 |
| D | NAP603 |
| D | HOH727 |
| D | HOH766 |
| D | HOH796 |
| D | HOH818 |
| site_id | AD6 |
| Number of Residues | 24 |
| Details | binding site for residue NAP D 603 |
| Chain | Residue |
| D | LYS100 |
| D | GLN102 |
| D | PRO217 |
| D | SER254 |
| D | GLY255 |
| D | GLN256 |
| D | SER257 |
| D | GLU260 |
| D | ARG279 |
| D | ASN323 |
| D | TYR324 |
| D | SER325 |
| D | ALA404 |
| D | THR405 |
| D | GLY406 |
| D | FAD602 |
| D | HOH707 |
| D | HOH738 |
| D | HOH744 |
| D | HOH747 |
| D | HOH799 |
| D | HOH854 |
| D | HOH890 |
| D | HOH893 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue CA D 604 |
| Chain | Residue |
| C | SER138 |
| C | HOH739 |
| C | HOH918 |
| D | ASP288 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 96 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22928747","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
