6X0H

Structure of oxidized SidA ornithine hydroxylase with the FAD in the "out" conformation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004497	molecular_function	monooxygenase activity
A	0004499	molecular_function	N,N-dimethylaniline monooxygenase activity
A	0005506	molecular_function	iron ion binding
A	0006696	biological_process	ergosterol biosynthetic process
A	0006879	biological_process	intracellular iron ion homeostasis
A	0010106	biological_process	cellular response to iron ion starvation
A	0019290	biological_process	siderophore biosynthetic process
A	0031169	biological_process	ferrichrome biosynthetic process
A	0031172	molecular_function	ornithine N5-monooxygenase activity
A	0033214	biological_process	siderophore-iron import into cell
A	0044550	biological_process	secondary metabolite biosynthetic process
A	0070401	molecular_function	NADP+ binding
B	0004497	molecular_function	monooxygenase activity
B	0004499	molecular_function	N,N-dimethylaniline monooxygenase activity
B	0005506	molecular_function	iron ion binding
B	0006696	biological_process	ergosterol biosynthetic process
B	0006879	biological_process	intracellular iron ion homeostasis
B	0010106	biological_process	cellular response to iron ion starvation
B	0019290	biological_process	siderophore biosynthetic process
B	0031169	biological_process	ferrichrome biosynthetic process
B	0031172	molecular_function	ornithine N5-monooxygenase activity
B	0033214	biological_process	siderophore-iron import into cell
B	0044550	biological_process	secondary metabolite biosynthetic process
B	0070401	molecular_function	NADP+ binding
C	0004497	molecular_function	monooxygenase activity
C	0004499	molecular_function	N,N-dimethylaniline monooxygenase activity
C	0005506	molecular_function	iron ion binding
C	0006696	biological_process	ergosterol biosynthetic process
C	0006879	biological_process	intracellular iron ion homeostasis
C	0010106	biological_process	cellular response to iron ion starvation
C	0019290	biological_process	siderophore biosynthetic process
C	0031169	biological_process	ferrichrome biosynthetic process
C	0031172	molecular_function	ornithine N5-monooxygenase activity
C	0033214	biological_process	siderophore-iron import into cell
C	0044550	biological_process	secondary metabolite biosynthetic process
C	0070401	molecular_function	NADP+ binding
D	0004497	molecular_function	monooxygenase activity
D	0004499	molecular_function	N,N-dimethylaniline monooxygenase activity
D	0005506	molecular_function	iron ion binding
D	0006696	biological_process	ergosterol biosynthetic process
D	0006879	biological_process	intracellular iron ion homeostasis
D	0010106	biological_process	cellular response to iron ion starvation
D	0019290	biological_process	siderophore biosynthetic process
D	0031169	biological_process	ferrichrome biosynthetic process
D	0031172	molecular_function	ornithine N5-monooxygenase activity
D	0033214	biological_process	siderophore-iron import into cell
D	0044550	biological_process	secondary metabolite biosynthetic process
D	0070401	molecular_function	NADP+ binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	29
Details	binding site for residue FAD A 601

Chain	Residue
A	GLY46
A	HIS91
A	MET94
A	ARG144
A	GLU166
A	GLU167
A	VAL168
A	ALA209
A	ILE210
A	GLY211
A	TYR324
A	GLY48
A	TYR407
A	ARG409
A	SER466
A	LEU467
A	LEU468
A	HOH747
A	HOH767
A	HOH784
A	HOH796
A	HOH808
A	PRO49
A	ALA50
A	LEU82
A	GLU83
A	ARG84
A	GLN85
A	TRP90

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ACT A 602

Chain	Residue
A	ILE103
A	LYS107
A	PHE296
A	SER469

---

site_id	AC3
Number of Residues	4
Details	binding site for residue PGE A 603

Chain	Residue
A	ARG84
A	SER92
A	LYS231
A	HOH803

---

site_id	AC4
Number of Residues	2
Details	binding site for residue CA A 604

Chain	Residue
A	SER138
B	ASP288

---

site_id	AC5
Number of Residues	31
Details	binding site for residue FAD B 601

Chain	Residue
B	GLY46
B	GLY48
B	PRO49
B	ALA50
B	LEU82
B	GLU83
B	ARG84
B	GLN85
B	TRP90
B	HIS91
B	MET94
B	GLU166
B	GLU167
B	VAL168
B	ALA209
B	ILE210
B	GLY211
B	ASN323
B	TYR324
B	TYR407
B	ARG409
B	SER466
B	LEU467
B	LEU468
B	HOH710
B	HOH757
B	HOH772
B	HOH784
B	HOH785
B	HOH790
B	HOH832

---

site_id	AC6
Number of Residues	4
Details	binding site for residue ACT B 602

Chain	Residue
B	ILE103
B	LYS107
B	PHE296
B	SER469

---

site_id	AC7
Number of Residues	27
Details	binding site for residue FAD C 601

Chain	Residue
C	HOH795
C	HOH801
C	GLY46
C	GLY48
C	PRO49
C	ALA50
C	GLU83
C	ARG84
C	GLN85
C	TRP90
C	HIS91
C	MET94
C	GLU166
C	GLU167
C	VAL168
C	ALA209
C	ILE210
C	GLY211
C	TYR324
C	TYR407
C	ARG409
C	SER466
C	LEU468
C	HOH703
C	HOH728
C	HOH746
C	HOH774

---

site_id	AC8
Number of Residues	5
Details	binding site for residue ACT C 602

Chain	Residue
C	ILE103
C	LYS107
C	PHE296
C	SER469
C	HOH784

---

site_id	AC9
Number of Residues	3
Details	binding site for residue CA C 603

Chain	Residue
C	SER138
C	HOH811
D	ASP288

---

site_id	AD1
Number of Residues	25
Details	binding site for residue FAD D 601

Chain	Residue
D	GLY46
D	GLY48
D	PRO49
D	ALA50
D	LEU82
D	GLU83
D	ARG84
D	GLN85
D	TRP90
D	HIS91
D	MET94
D	ARG144
D	GLU166
D	VAL168
D	ALA209
D	ILE210
D	GLY211
D	TYR324
D	TYR407
D	ARG409
D	SER466
D	LEU468
D	HOH722
D	HOH737
D	HOH745

---

site_id	AD2
Number of Residues	5
Details	binding site for residue ACT D 602

Chain	Residue
D	ILE103
D	LYS107
D	PHE296
D	SER469
D	HOH775

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	96
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22928747","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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