6WZQ

Structure of SARS-CoV-2 Nucleocapsid dimerization domain, P21 form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0019013	cellular_component	viral nucleocapsid
B	0003723	molecular_function	RNA binding
B	0019013	cellular_component	viral nucleocapsid
C	0003723	molecular_function	RNA binding
C	0019013	cellular_component	viral nucleocapsid
D	0003723	molecular_function	RNA binding
D	0019013	cellular_component	viral nucleocapsid

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue SO4 A 401

Chain	Residue
A	GLY275
A	ARG276

---

site_id	AC2
Number of Residues	2
Details	binding site for residue SO4 A 402

Chain	Residue
A	TRP330
D	GLU280

---

site_id	AC3
Number of Residues	1
Details	binding site for residue SO4 B 401

Chain	Residue
B	ARG262

---

site_id	AC4
Number of Residues	4
Details	binding site for residue SO4 C 401

Chain	Residue
C	ARG259
C	ARG262
C	HOH517
C	HOH521

---

site_id	AC5
Number of Residues	5
Details	binding site for residue SO4 C 402

Chain	Residue
A	HIS300
C	LYS266
C	ARG293
C	GLN294
D	HOH505

---

site_id	AC6
Number of Residues	2
Details	binding site for residue SO4 D 401

Chain	Residue
D	ARG262
D	HOH542

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	412
Details	Region: {"description":"Dimerization","evidences":[{"source":"HAMAP-Rule","id":"MF_04096","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	320
Details	Region: {"description":"Putative NLRP3 binding","evidences":[{"source":"PubMed","id":"34341353","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	32
Details	Motif: {"description":"Nuclear localization signal","evidences":[{"source":"UniProtKB","id":"P59595","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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