6WWI
Apo KIF14[391-755] in complex with a microtubule
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000226 | biological_process | microtubule cytoskeleton organization |
A | 0000278 | biological_process | mitotic cell cycle |
A | 0003924 | molecular_function | GTPase activity |
A | 0005200 | molecular_function | structural constituent of cytoskeleton |
A | 0005525 | molecular_function | GTP binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005856 | cellular_component | cytoskeleton |
A | 0005874 | cellular_component | microtubule |
A | 0007017 | biological_process | microtubule-based process |
A | 0015630 | cellular_component | microtubule cytoskeleton |
A | 0016787 | molecular_function | hydrolase activity |
A | 0046872 | molecular_function | metal ion binding |
B | 0003924 | molecular_function | GTPase activity |
B | 0005200 | molecular_function | structural constituent of cytoskeleton |
B | 0005525 | molecular_function | GTP binding |
B | 0005874 | cellular_component | microtubule |
B | 0007017 | biological_process | microtubule-based process |
K | 0003777 | molecular_function | microtubule motor activity |
K | 0005524 | molecular_function | ATP binding |
K | 0007018 | biological_process | microtubule-based movement |
K | 0008017 | molecular_function | microtubule binding |
Functional Information from PROSITE/UniProt
site_id | PS00227 |
Number of Residues | 7 |
Details | TUBULIN Tubulin subunits alpha, beta, and gamma signature. GGGTGSG |
Chain | Residue | Details |
B | GLY140-GLY146 | |
A | GLY142-GLY148 |
site_id | PS00228 |
Number of Residues | 4 |
Details | TUBULIN_B_AUTOREG Tubulin-beta mRNA autoregulation signal. MREI |
Chain | Residue | Details |
B | MET1-ILE4 |
site_id | PS00411 |
Number of Residues | 12 |
Details | KINESIN_MOTOR_1 Kinesin motor domain signature. SRInLVDLAGSE |
Chain | Residue | Details |
K | SER632-GLU643 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00283, ECO:0007744|PDB:4OZQ |
Chain | Residue | Details |
K | GLY482 |
site_id | SWS_FT_FI2 |
Number of Residues | 8 |
Details | BINDING: BINDING => ECO:0000250|UniProtKB:P68363 |
Chain | Residue | Details |
A | GLN11 | |
A | GLU71 | |
A | SER140 | |
A | GLY144 | |
A | THR145 | |
A | THR179 | |
A | ASN206 | |
A | ASN228 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | SITE: Involved in polymerization => ECO:0000250 |
Chain | Residue | Details |
A | TYR451 |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | MOD_RES: N6-acetyllysine; alternate => ECO:0000250|UniProtKB:P68363 |
Chain | Residue | Details |
A | LYS40 |
site_id | SWS_FT_FI5 |
Number of Residues | 2 |
Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P68363 |
Chain | Residue | Details |
A | SER48 | |
A | SER232 |
site_id | SWS_FT_FI6 |
Number of Residues | 1 |
Details | MOD_RES: 3'-nitrotyrosine => ECO:0000250|UniProtKB:P68373 |
Chain | Residue | Details |
A | TYR282 |
site_id | SWS_FT_FI7 |
Number of Residues | 1 |
Details | MOD_RES: Omega-N-methylarginine => ECO:0000250|UniProtKB:P68363 |
Chain | Residue | Details |
A | ARG339 |
site_id | SWS_FT_FI8 |
Number of Residues | 1 |
Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P68373 |
Chain | Residue | Details |
A | SER439 |
site_id | SWS_FT_FI9 |
Number of Residues | 1 |
Details | MOD_RES: 5-glutamyl polyglutamate => ECO:0000250|UniProtKB:P68363 |
Chain | Residue | Details |
A | GLU443 |
site_id | SWS_FT_FI10 |
Number of Residues | 1 |
Details | MOD_RES: 5-glutamyl polyglutamate => ECO:0000250|UniProtKB:P68369 |
Chain | Residue | Details |
A | GLU445 |
site_id | SWS_FT_FI11 |
Number of Residues | 1 |
Details | MOD_RES: 3'-nitrotyrosine => ECO:0000250|UniProtKB:Q71U36 |
Chain | Residue | Details |
A | TYR451 |
site_id | SWS_FT_FI12 |
Number of Residues | 3 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P68363 |
Chain | Residue | Details |
A | LYS326 | |
A | LYS370 |