6WVD
Human JAGN1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002376 | biological_process | immune system process |
| A | 0002446 | biological_process | neutrophil mediated immunity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0006091 | biological_process | generation of precursor metabolites and energy |
| A | 0006887 | biological_process | exocytosis |
| A | 0007029 | biological_process | endoplasmic reticulum organization |
| A | 0008218 | biological_process | bioluminescence |
| A | 0015031 | biological_process | protein transport |
| A | 0016020 | cellular_component | membrane |
| A | 0016192 | biological_process | vesicle-mediated transport |
| A | 0030223 | biological_process | neutrophil differentiation |
| A | 0038158 | biological_process | granulocyte colony-stimulating factor signaling pathway |
| A | 0050832 | biological_process | defense response to fungus |
| A | 0061179 | biological_process | negative regulation of insulin secretion involved in cellular response to glucose stimulus |
| A | 1990266 | biological_process | neutrophil migration |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue OLC A 501 |
| Chain | Residue |
| A | GLU180 |
| A | SER287 |
| A | SER290 |
| A | ILE291 |
| A | GLN301 |
| A | VAL302 |
| A | TRP305 |
| A | TYR309 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue OLC A 502 |
| Chain | Residue |
| A | ARG275 |
| A | GLY277 |
| A | TRP305 |
| A | TYR308 |
| A | TYR274 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: (Z)-2,3-didehydrotyrosine => ECO:0000269|PubMed:8448132 |
| Chain | Residue | Details |
| A | VAL68 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | CROSSLNK: 5-imidazolinone (Ser-Gly) => ECO:0000269|PubMed:8448132 |
| Chain | Residue | Details |
| A | CRO66 | |
| A | GLN69 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 65 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | MET145-LYS183 | |
| A | PRO237-ASN240 | |
| A | HIS303-LYS327 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 80 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU184-LEU204 | |
| A | TYR216-PHE236 | |
| A | ILE241-TYR261 | |
| A | PHE282-VAL302 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 29 |
| Details | TOPO_DOM: Lumenal => ECO:0000255 |
| Chain | Residue | Details |
| A | ARG205-PRO215 | |
| A | GLY262-ARG281 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231 |
| Chain | Residue | Details |
| A | SER147 |
