6WT6

Structure of a metazoan TIR-STING receptor from C. gigas

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000045	biological_process	autophagosome assembly
A	0000166	molecular_function	nucleotide binding
A	0002218	biological_process	activation of innate immune response
A	0002376	biological_process	immune system process
A	0005776	cellular_component	autophagosome
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0006914	biological_process	autophagy
A	0007165	biological_process	signal transduction
A	0016239	biological_process	positive regulation of macroautophagy
A	0016787	molecular_function	hydrolase activity
A	0032481	biological_process	positive regulation of type I interferon production
A	0035438	molecular_function	cyclic-di-GMP binding
A	0045087	biological_process	innate immune response
A	0061507	molecular_function	2',3'-cyclic GMP-AMP binding
A	0061709	biological_process	reticulophagy
A	0061809	molecular_function	NAD+ nucleotidase, cyclic ADP-ribose generating

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU00204, ECO:0000305|PubMed:32877915

Chain	Residue	Details
A	GLU104

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0007744|PDB:6WT7

Chain	Residue	Details
A	ARG256

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