Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004674 | molecular_function | protein serine/threonine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue PZ4 A 701 |
| Chain | Residue |
| A | ARG408 |
| A | LEU522 |
| A | ASP534 |
| A | HOH841 |
| A | GLY409 |
| A | VAL414 |
| A | ALA427 |
| A | LYS429 |
| A | MET469 |
| A | GLU470 |
| A | LEU471 |
| A | LEU472 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue PZ4 B 701 |
| Chain | Residue |
| B | LEU406 |
| B | GLY409 |
| B | VAL414 |
| B | ALA427 |
| B | LYS429 |
| B | MET469 |
| B | GLU470 |
| B | LEU471 |
| B | LEU472 |
| B | LEU522 |
| B | ASP534 |
| B | HOH836 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 25 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGRGSFGEVHrMedkqtgfqc.........AVKK |
| Chain | Residue | Details |
| A | LEU406-LYS430 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IlHgDVKadNVLL |
| Chain | Residue | Details |
| A | ILE511-LEU523 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20682767","evidenceCode":"ECO:0000269"}]} |
