Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6WP1

The Crystal Structure of Apo Domain-Swapped Trimer Q108K:K40L:T51K Variant of HCRBPII

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001523	biological_process	retinoid metabolic process
A	0005501	molecular_function	retinoid binding
A	0005504	molecular_function	fatty acid binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006776	biological_process	vitamin A metabolic process
A	0008289	molecular_function	lipid binding
A	0008544	biological_process	epidermis development
A	0015908	biological_process	fatty acid transport
A	0016918	molecular_function	retinal binding
A	0019841	molecular_function	retinol binding
A	0140104	molecular_function	molecular carrier activity
B	0001523	biological_process	retinoid metabolic process
B	0005501	molecular_function	retinoid binding
B	0005504	molecular_function	fatty acid binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006776	biological_process	vitamin A metabolic process
B	0008289	molecular_function	lipid binding
B	0008544	biological_process	epidermis development
B	0015908	biological_process	fatty acid transport
B	0016918	molecular_function	retinal binding
B	0019841	molecular_function	retinol binding
B	0140104	molecular_function	molecular carrier activity
C	0001523	biological_process	retinoid metabolic process
C	0005501	molecular_function	retinoid binding
C	0005504	molecular_function	fatty acid binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006776	biological_process	vitamin A metabolic process
C	0008289	molecular_function	lipid binding
C	0008544	biological_process	epidermis development
C	0015908	biological_process	fatty acid transport
C	0016918	molecular_function	retinal binding
C	0019841	molecular_function	retinol binding
C	0140104	molecular_function	molecular carrier activity
D	0001523	biological_process	retinoid metabolic process
D	0005501	molecular_function	retinoid binding
D	0005504	molecular_function	fatty acid binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006776	biological_process	vitamin A metabolic process
D	0008289	molecular_function	lipid binding
D	0008544	biological_process	epidermis development
D	0015908	biological_process	fatty acid transport
D	0016918	molecular_function	retinal binding
D	0019841	molecular_function	retinol binding
D	0140104	molecular_function	molecular carrier activity
E	0001523	biological_process	retinoid metabolic process
E	0005501	molecular_function	retinoid binding
E	0005504	molecular_function	fatty acid binding
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006776	biological_process	vitamin A metabolic process
E	0008289	molecular_function	lipid binding
E	0008544	biological_process	epidermis development
E	0015908	biological_process	fatty acid transport
E	0016918	molecular_function	retinal binding
E	0019841	molecular_function	retinol binding
E	0140104	molecular_function	molecular carrier activity
F	0001523	biological_process	retinoid metabolic process
F	0005501	molecular_function	retinoid binding
F	0005504	molecular_function	fatty acid binding
F	0005634	cellular_component	nucleus
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006776	biological_process	vitamin A metabolic process
F	0008289	molecular_function	lipid binding
F	0008544	biological_process	epidermis development
F	0015908	biological_process	fatty acid transport
F	0016918	molecular_function	retinal binding
F	0019841	molecular_function	retinol binding
F	0140104	molecular_function	molecular carrier activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue ACT B 201

Chain	Residue
B	ASP47
B	ASP91

site_id	AC2
Number of Residues	4
Details	binding site for residue GOL B 203

Chain	Residue
B	ILE110
B	GLU111
C	THR1
F	GLY90

site_id	AC3
Number of Residues	5
Details	binding site for residue GOL B 204

Chain	Residue
D	ASP78
D	ASN79
B	ASP24
B	ASP26
D	LYS31

site_id	AC4
Number of Residues	3
Details	binding site for residue GOL C 201

Chain	Residue
C	ASP123
C	GLN124
D	ASN15

site_id	AC5
Number of Residues	3
Details	binding site for residue GOL C 202

Chain	Residue
B	LEU77
C	ASP24
C	ILE25

site_id	AC6
Number of Residues	4
Details	binding site for residue GOL C 203

Chain	Residue
C	LYS31
C	ARG35
C	SER76
D	ILE32

site_id	AC7
Number of Residues	2
Details	binding site for residue ACT D 201

Chain	Residue
D	ARG2
D	ASP47

site_id	AC8
Number of Residues	1
Details	binding site for residue ACT D 202

Chain	Residue
D	ASP63

site_id	AC9
Number of Residues	3
Details	binding site for residue GOL D 203

Chain	Residue
D	GLU72
D	LEU77
D	GLN97

site_id	AD1
Number of Residues	3
Details	binding site for residue ACT E 301

Chain	Residue
D	ASP63
D	THR65
E	ARG2

site_id	AD2
Number of Residues	3
Details	binding site for residue GOL E 302

Chain	Residue
E	VAL92
E	TRP109
E	GLU118

Functional Information from PROSITE/UniProt

site_id	PS00214
Number of Residues	18
Details	FABP Cytosolic fatty-acid binding proteins signature. GTWeMesNeNFEgYMKAL

Chain	Residue	Details
A	GLY6-LEU23

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269\|PubMed:18076076

Chain	Residue	Details
A	LEU40
E	LYS108
F	LEU40
F	LYS108
A	LYS108
B	LEU40
B	LYS108
C	LEU40
C	LYS108
D	LEU40
D	LYS108
E	LEU40

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)