Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
| E | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
| H | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 501 |
| Chain | Residue |
| A | GLY113 |
| A | HIS115 |
| A | THR374 |
| A | VAL376 |
| A | GLU377 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 502 |
| Chain | Residue |
| A | GLY248 |
| A | ARG250 |
| A | LYS273 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | HIS289 |
| A | LYS290 |
| A | HOH633 |
| A | ARG270 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue NA A 504 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue GOL B 201 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue GOL D 601 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue NA D 602 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue GOL G 501 |
| Chain | Residue |
| G | HIS212 |
| G | ARG214 |
| G | VAL256 |
| G | ASP257 |
| G | LEU296 |
| G | ARG337 |
| G | ARG384 |
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. IVTGssDsTVRVWDV |
| Chain | Residue | Details |
| A | ILE180-VAL194 | |
| A | MET220-MET234 | |
| A | VAL303-ILE317 | |
| A | ILE343-LEU357 | |
| A | ILE392-PHE406 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 114 |
| Details | Domain: {"description":"F-box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00080","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 111 |
| Details | Repeat: {"description":"WD 1"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 111 |
| Details | Repeat: {"description":"WD 2"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 111 |
| Details | Repeat: {"description":"WD 3"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 111 |
| Details | Repeat: {"description":"WD 4"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 117 |
| Details | Repeat: {"description":"WD 5"} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 108 |
| Details | Repeat: {"description":"WD 6"} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI9 |
| Number of Residues | 6 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI10 |
| Number of Residues | 59 |
| Details | Region: {"description":"Interaction with the F-box domain of F-box proteins","evidences":[{"source":"PubMed","id":"35982156","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7Z8B","evidenceCode":"ECO:0007744"}]} |
6WNX
