6WN6
Crystal structure of 3-keto-D-glucoside 4-epimerase, YcjR, from E. coli, apo form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0016857 | molecular_function | racemase and epimerase activity, acting on carbohydrates and derivatives |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0016857 | molecular_function | racemase and epimerase activity, acting on carbohydrates and derivatives |
| B | 0030145 | molecular_function | manganese ion binding |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0005829 | cellular_component | cytosol |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0016857 | molecular_function | racemase and epimerase activity, acting on carbohydrates and derivatives |
| C | 0030145 | molecular_function | manganese ion binding |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0005829 | cellular_component | cytosol |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0016857 | molecular_function | racemase and epimerase activity, acting on carbohydrates and derivatives |
| D | 0030145 | molecular_function | manganese ion binding |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue MN A 301 |
| Chain | Residue |
| A | GLU149 |
| A | ASP182 |
| A | HIS208 |
| A | GLU243 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | EDO303 |
| A | EDO304 |
| A | LEU151 |
| A | GLN155 |
| A | HIS185 |
| A | ARG214 |
| A | GLU243 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | TRP105 |
| A | EDO302 |
| A | EDO304 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | GLY244 |
| A | EDO302 |
| A | EDO303 |
| A | EDO306 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | ILE209 |
| A | ALA210 |
| A | TYR215 |
| A | GLN216 |
| A | PRO217 |
| A | TYR242 |
| A | GLY244 |
| A | ARG245 |
| A | TYR255 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | GLN9 |
| A | ASN10 |
| A | GLN11 |
| A | GLU243 |
| A | GLY244 |
| A | EDO304 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 307 |
| Chain | Residue |
| A | GLN9 |
| A | ASN10 |
| A | GLU34 |
| A | ILE35 |
| A | ASP36 |
| A | HOH405 |
| A | HOH429 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 308 |
| Chain | Residue |
| A | ARG245 |
| B | ARG153 |
| B | HOH409 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 309 |
| Chain | Residue |
| A | MET158 |
| A | ASN160 |
| A | ASP164 |
| A | EDO310 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 310 |
| Chain | Residue |
| A | THR161 |
| A | ASP164 |
| A | EDO309 |
| A | HOH482 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 311 |
| Chain | Residue |
| A | ARG125 |
| A | ASP164 |
| A | ARG167 |
| A | TYR168 |
| A | EDO312 |
| A | EDO314 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 312 |
| Chain | Residue |
| A | LEU121 |
| A | ASP124 |
| A | MET158 |
| A | TYR168 |
| A | EDO311 |
| A | HOH404 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 313 |
| Chain | Residue |
| A | GLY63 |
| A | GLY64 |
| A | TYR65 |
| A | TRP68 |
| A | HOH402 |
| A | HOH425 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 314 |
| Chain | Residue |
| A | ARG125 |
| A | SER129 |
| A | ARG167 |
| A | GLU171 |
| A | EDO311 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 315 |
| Chain | Residue |
| A | LYS82 |
| A | GLU85 |
| A | HOH406 |
| D | ARG141 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 316 |
| Chain | Residue |
| A | ILE169 |
| A | ASP173 |
| A | LEU174 |
| A | LYS175 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue MN B 301 |
| Chain | Residue |
| B | GLU149 |
| B | ASP182 |
| B | HIS208 |
| B | GLU243 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 302 |
| Chain | Residue |
| B | MET158 |
| B | ASN160 |
| B | ASP164 |
| B | EDO306 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 303 |
| Chain | Residue |
| B | LEU121 |
| B | ASP124 |
| B | MET158 |
| B | TYR168 |
| B | HOH406 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 304 |
| Chain | Residue |
| B | EDO305 |
| B | ARG125 |
| B | ASP164 |
| B | ARG167 |
| B | TYR168 |
| site_id | AE3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 305 |
| Chain | Residue |
| B | ARG125 |
| B | SER129 |
| B | ARG167 |
| B | TYR168 |
| B | GLU171 |
| B | EDO304 |
| site_id | AE4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 306 |
| Chain | Residue |
| B | THR161 |
| B | ASP164 |
| B | EDO302 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 307 |
| Chain | Residue |
| B | LEU151 |
| B | GLN155 |
| B | HIS185 |
| B | ARG214 |
| B | GLU243 |
| B | EDO313 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 308 |
| Chain | Residue |
| B | CYS62 |
| B | TRP68 |
| B | PRO102 |
| B | EDO312 |
| B | HOH408 |
| B | HOH420 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 309 |
| Chain | Residue |
| B | GLY244 |
| B | ARG245 |
| B | EDO310 |
| B | EDO313 |
| B | HOH410 |
| site_id | AE8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 310 |
| Chain | Residue |
| B | GLN9 |
| B | ASN10 |
| B | GLN11 |
| B | GLU243 |
| B | GLY244 |
| B | EDO309 |
| site_id | AE9 |
| Number of Residues | 10 |
| Details | binding site for residue EDO B 311 |
| Chain | Residue |
| B | GLN11 |
| B | ILE209 |
| B | ALA210 |
| B | TYR215 |
| B | GLN216 |
| B | PRO217 |
| B | TYR242 |
| B | GLY244 |
| B | ARG245 |
| B | TYR255 |
| site_id | AF1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 312 |
| Chain | Residue |
| B | GLY63 |
| B | GLY64 |
| B | TYR65 |
| B | TRP68 |
| B | EDO308 |
| site_id | AF2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 313 |
| Chain | Residue |
| B | EDO307 |
| B | EDO309 |
| B | HOH410 |
| site_id | AF3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 314 |
| Chain | Residue |
| A | ARG153 |
| A | HOH420 |
| B | ARG245 |
| B | HOH467 |
| site_id | AF4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 315 |
| Chain | Residue |
| B | LEU222 |
| B | ASP223 |
| site_id | AF5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 316 |
| Chain | Residue |
| B | LYS38 |
| B | GLY64 |
| B | GLN83 |
| B | ARG86 |
| site_id | AF6 |
| Number of Residues | 4 |
| Details | binding site for residue MN C 301 |
| Chain | Residue |
| C | GLU149 |
| C | ASP182 |
| C | HIS208 |
| C | GLU243 |
| site_id | AF7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 302 |
| Chain | Residue |
| C | GLY244 |
| C | ARG245 |
| C | EDO303 |
| C | EDO305 |
| C | EDO307 |
| site_id | AF8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 303 |
| Chain | Residue |
| C | LEU151 |
| C | GLN155 |
| C | HIS185 |
| C | ARG214 |
| C | GLU243 |
| C | EDO302 |
| C | EDO307 |
| site_id | AF9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 304 |
| Chain | Residue |
| C | GLN9 |
| C | ASN10 |
| C | GLU34 |
| C | ILE35 |
| C | ASP36 |
| C | HOH406 |
| C | HOH460 |
| site_id | AG1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 305 |
| Chain | Residue |
| C | GLN9 |
| C | ASN10 |
| C | GLN11 |
| C | GLU243 |
| C | GLY244 |
| C | EDO302 |
| site_id | AG2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 306 |
| Chain | Residue |
| C | GLY63 |
| C | GLY64 |
| C | TYR65 |
| C | TRP68 |
| site_id | AG3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO C 307 |
| Chain | Residue |
| C | EDO302 |
| C | EDO303 |
| site_id | AG4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 308 |
| Chain | Residue |
| C | CYS62 |
| C | GLY63 |
| C | PRO102 |
| C | HOH411 |
| C | HOH417 |
| site_id | AG5 |
| Number of Residues | 10 |
| Details | binding site for residue EDO C 309 |
| Chain | Residue |
| C | ILE209 |
| C | ALA210 |
| C | ARG214 |
| C | TYR215 |
| C | GLN216 |
| C | PRO217 |
| C | TYR242 |
| C | GLY244 |
| C | ARG245 |
| C | TYR255 |
| site_id | AG6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 310 |
| Chain | Residue |
| C | MET158 |
| C | ASN160 |
| C | ASP164 |
| C | EDO311 |
| site_id | AG7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 311 |
| Chain | Residue |
| C | THR161 |
| C | ASP164 |
| C | ARG167 |
| C | EDO310 |
| D | ARG247 |
| site_id | AG8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 312 |
| Chain | Residue |
| C | ASP124 |
| C | MET158 |
| C | TYR168 |
| C | EDO313 |
| C | HOH410 |
| site_id | AG9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 313 |
| Chain | Residue |
| C | ARG125 |
| C | ASP164 |
| C | ARG167 |
| C | TYR168 |
| C | EDO312 |
| C | EDO314 |
| site_id | AH1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 314 |
| Chain | Residue |
| C | ARG125 |
| C | ARG167 |
| C | TYR168 |
| C | GLU171 |
| C | EDO313 |
| site_id | AH2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO C 315 |
| Chain | Residue |
| C | LEU222 |
| C | ASP223 |
| site_id | AH3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 316 |
| Chain | Residue |
| C | ARG247 |
| C | HOH435 |
| D | ASP191 |
| site_id | AH4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 317 |
| Chain | Residue |
| B | LYS82 |
| B | GLU85 |
| B | HOH453 |
| C | ARG141 |
| site_id | AH5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 318 |
| Chain | Residue |
| C | ASN10 |
| C | GLU16 |
| C | LYS21 |
| C | LEU39 |
| site_id | AH6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 319 |
| Chain | Residue |
| C | LYS3 |
| C | MET4 |
| C | LYS5 |
| C | TYR236 |
| C | GLY238 |
| site_id | AH7 |
| Number of Residues | 4 |
| Details | binding site for residue MN D 301 |
| Chain | Residue |
| D | GLU149 |
| D | ASP182 |
| D | HIS208 |
| D | GLU243 |
| site_id | AH8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO D 302 |
| Chain | Residue |
| D | LEU151 |
| D | GLN155 |
| D | HIS185 |
| D | ARG214 |
| D | GLU243 |
| D | EDO303 |
| D | EDO304 |
| site_id | AH9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 303 |
| Chain | Residue |
| C | ARG111 |
| D | TRP105 |
| D | EDO302 |
| D | EDO304 |
| site_id | AI1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 304 |
| Chain | Residue |
| D | GLY244 |
| D | ARG245 |
| D | EDO302 |
| D | EDO303 |
| D | EDO305 |
| site_id | AI2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO D 305 |
| Chain | Residue |
| D | GLN9 |
| D | ASN10 |
| D | GLN11 |
| D | GLU243 |
| D | GLY244 |
| D | EDO304 |
| D | EDO311 |
| site_id | AI3 |
| Number of Residues | 9 |
| Details | binding site for residue EDO D 306 |
| Chain | Residue |
| D | GLN11 |
| D | ILE209 |
| D | ALA210 |
| D | TYR215 |
| D | GLN216 |
| D | TYR242 |
| D | GLY244 |
| D | ARG245 |
| D | TYR255 |
| site_id | AI4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 307 |
| Chain | Residue |
| D | CYS62 |
| D | GLY63 |
| D | PRO102 |
| D | EDO313 |
| D | HOH409 |
| D | HOH420 |
| site_id | AI5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 308 |
| Chain | Residue |
| D | LEU121 |
| D | ASP124 |
| D | MET158 |
| D | TYR168 |
| D | EDO316 |
| D | HOH433 |
| site_id | AI6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 309 |
| Chain | Residue |
| D | MET158 |
| D | ASN160 |
| D | ASP164 |
| D | EDO310 |
| D | HOH484 |
| site_id | AI7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 310 |
| Chain | Residue |
| C | ARG247 |
| D | THR161 |
| D | ASP164 |
| D | ARG167 |
| D | EDO309 |
| site_id | AI8 |
| Number of Residues | 8 |
| Details | binding site for residue EDO D 311 |
| Chain | Residue |
| D | GLN9 |
| D | ASN10 |
| D | GLU34 |
| D | ILE35 |
| D | ASP36 |
| D | EDO305 |
| D | HOH411 |
| D | HOH459 |
| site_id | AI9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 312 |
| Chain | Residue |
| C | ARG153 |
| C | HOH426 |
| D | ARG245 |
| D | HOH485 |
| site_id | AJ1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 313 |
| Chain | Residue |
| D | GLY63 |
| D | GLY64 |
| D | TYR65 |
| D | EDO307 |
| site_id | AJ2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO D 314 |
| Chain | Residue |
| D | LEU222 |
| D | ASP223 |
| site_id | AJ3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 315 |
| Chain | Residue |
| D | ARG125 |
| D | SER129 |
| D | TYR168 |
| D | GLU171 |
| D | EDO316 |
| site_id | AJ4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 316 |
| Chain | Residue |
| D | ARG125 |
| D | ASP164 |
| D | ARG167 |
| D | TYR168 |
| D | EDO308 |
| D | EDO315 |
| site_id | AJ5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 317 |
| Chain | Residue |
| C | ASP191 |
| C | ASN192 |
| D | GLY218 |
| D | SER219 |
| D | GLY220 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"UniProtKB","id":"Q9WYP7","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9WYP7","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
