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6WE4

Human PARP14 (ARTD8), catalytic fragment in complex with compound 2

Functional Information from GO Data
ChainGOidnamespacecontents
A0003950molecular_functionNAD+-protein poly-ADP-ribosyltransferase activity
B0003950molecular_functionNAD+-protein poly-ADP-ribosyltransferase activity
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue FDR A 1901
ChainResidue
AHIS1682
AGLY1683
ATYR1714
ASER1722
ATYR1727

site_idAC2
Number of Residues8
Detailsbinding site for residue EDO A 1902
ChainResidue
BPHE1617
BVAL1689
BASN1693
BEDO1905
APHE1617
AASN1693
AARG1694
AHOH2001

site_idAC3
Number of Residues6
Detailsbinding site for residue EDO A 1903
ChainResidue
APRO1690
AHIS1691
AHOH2004
BASP1731
BARG1735
BHIS1737

site_idAC4
Number of Residues3
Detailsbinding site for residue EDO A 1904
ChainResidue
AHIS1737
ATHR1798
BGLY1687

site_idAC5
Number of Residues2
Detailsbinding site for residue EDO A 1905
ChainResidue
AILE1651
ATYR1792

site_idAC6
Number of Residues3
Detailsbinding site for residue EDO A 1906
ChainResidue
ACYS1618
AGLN1652
AHOH2017

site_idAC7
Number of Residues5
Detailsbinding site for residue EDO A 1907
ChainResidue
ALEU1755
AVAL1757
APRO1758
APRO1759
AHOH2003

site_idAC8
Number of Residues14
Detailsbinding site for residue TYG B 1901
ChainResidue
BHIS1682
BGLY1683
BTHR1684
BASP1685
BTYR1714
BTYR1721
BSER1722
BTHR1726
BTYR1727
BARG1729
BPRO1763
BGLN1764
BPRO1766
BHOH2010

site_idAC9
Number of Residues5
Detailsbinding site for residue GOL B 1902
ChainResidue
BHIS1682
BTHR1684
BHOH2001
BHOH2021
BHOH2041

site_idAD1
Number of Residues11
Detailsbinding site for residue GOL B 1903
ChainResidue
BPHE1697
BASN1698
BARG1699
BGLY1710
BLYS1711
BTHR1713
BALA1785
BPHE1786
BTYR1787
BASP1788
BHOH2034

site_idAD2
Number of Residues3
Detailsbinding site for residue EDO B 1904
ChainResidue
BGLN1652
BASN1653
BTYR1792

site_idAD3
Number of Residues7
Detailsbinding site for residue EDO B 1905
ChainResidue
ALYS1647
AGLU1649
AEDO1902
AHOH2001
BPHE1617
BPRO1690
BARG1694

site_idAD4
Number of Residues7
Detailsbinding site for residue EDO B 1906
ChainResidue
BLYS1663
BMET1667
BLYS1670
BHIS1753
BSER1754
BHOH2004
BHOH2014

site_idAD5
Number of Residues4
Detailsbinding site for residue EDO B 1907
ChainResidue
BALA1662
BTHR1666
BHOH2004
BHOH2012

226707

PDB entries from 2024-10-30

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