6WB9

Structure of the S. cerevisiae ER membrane complex

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0072546	cellular_component	EMC complex
2	0003674	molecular_function	molecular_function
2	0005515	molecular_function	protein binding
2	0005634	cellular_component	nucleus
2	0005783	cellular_component	endoplasmic reticulum
2	0005789	cellular_component	endoplasmic reticulum membrane
2	0006644	biological_process	phospholipid metabolic process
2	0015914	biological_process	phospholipid transport
2	0032977	molecular_function	membrane insertase activity
2	0034975	biological_process	protein folding in endoplasmic reticulum
2	0045050	biological_process	protein insertion into ER membrane by stop-transfer membrane-anchor sequence
2	0071816	biological_process	tail-anchored membrane protein insertion into ER membrane
2	0072546	cellular_component	EMC complex
3	0003674	molecular_function	molecular_function
3	0005789	cellular_component	endoplasmic reticulum membrane
3	0006644	biological_process	phospholipid metabolic process
3	0015914	biological_process	phospholipid transport
3	0016020	cellular_component	membrane
3	0032977	molecular_function	membrane insertase activity
3	0034975	biological_process	protein folding in endoplasmic reticulum
3	0045050	biological_process	protein insertion into ER membrane by stop-transfer membrane-anchor sequence
3	0051087	molecular_function	protein-folding chaperone binding
3	0071816	biological_process	tail-anchored membrane protein insertion into ER membrane
3	0072546	cellular_component	EMC complex
4	0003674	molecular_function	molecular_function
4	0005783	cellular_component	endoplasmic reticulum
4	0005789	cellular_component	endoplasmic reticulum membrane
4	0006644	biological_process	phospholipid metabolic process
4	0015914	biological_process	phospholipid transport
4	0032977	molecular_function	membrane insertase activity
4	0034975	biological_process	protein folding in endoplasmic reticulum
4	0045050	biological_process	protein insertion into ER membrane by stop-transfer membrane-anchor sequence
4	0072546	cellular_component	EMC complex
5	0003674	molecular_function	molecular_function
5	0005515	molecular_function	protein binding
5	0005783	cellular_component	endoplasmic reticulum
5	0005789	cellular_component	endoplasmic reticulum membrane
5	0006644	biological_process	phospholipid metabolic process
5	0015914	biological_process	phospholipid transport
5	0032977	molecular_function	membrane insertase activity
5	0034975	biological_process	protein folding in endoplasmic reticulum
5	0045050	biological_process	protein insertion into ER membrane by stop-transfer membrane-anchor sequence
5	0072546	cellular_component	EMC complex
6	0000045	biological_process	autophagosome assembly
6	0003674	molecular_function	molecular_function
6	0005515	molecular_function	protein binding
6	0005783	cellular_component	endoplasmic reticulum
6	0005789	cellular_component	endoplasmic reticulum membrane
6	0006644	biological_process	phospholipid metabolic process
6	0015914	biological_process	phospholipid transport
6	0016020	cellular_component	membrane
6	0032977	molecular_function	membrane insertase activity
6	0034975	biological_process	protein folding in endoplasmic reticulum
6	0045050	biological_process	protein insertion into ER membrane by stop-transfer membrane-anchor sequence
6	0072546	cellular_component	EMC complex

Functional Information from PROSITE/UniProt

site_id	PS00923
Number of Residues	10
Details	ASP_GLU_RACEMASE_1 Aspartate and glutamate racemases signature 1. AMvCvNSSSN

Chain	Residue	Details
1	ALA101-ASN110

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	13
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	198
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	33
Details	Repeat: {"description":"TPR","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Topological domain: {"description":"Lumenal","evidences":[{"source":"UniProtKB","id":"Q9BV81","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	17
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---