6WAV

Crystal structure of PHF1 in complex with H3K36me3 substitution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006974	biological_process	cellular response to DNA damage stimulus
A	0031060	biological_process	regulation of histone methylation
A	0035064	molecular_function	methylated histone binding
B	0006974	biological_process	cellular response to DNA damage stimulus
B	0031060	biological_process	regulation of histone methylation
B	0035064	molecular_function	methylated histone binding
C	0006974	biological_process	cellular response to DNA damage stimulus
C	0031060	biological_process	regulation of histone methylation
C	0035064	molecular_function	methylated histone binding
D	0006974	biological_process	cellular response to DNA damage stimulus
D	0031060	biological_process	regulation of histone methylation
D	0035064	molecular_function	methylated histone binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue SO4 A 101

Chain	Residue
A	ASP55
A	SER56
A	ALA57
A	ARG58

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	114
Details	Domain: {"description":"Tudor"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"15983376","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16185088","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16267050","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16627869","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17194708","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"N6-methyllysine","evidences":[{"source":"PubMed","id":"15983376","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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