6WAV
Crystal structure of PHF1 in complex with H3K36me3 substitution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006974 | biological_process | cellular response to DNA damage stimulus |
| A | 0031060 | biological_process | regulation of histone methylation |
| A | 0035064 | molecular_function | methylated histone binding |
| B | 0006974 | biological_process | cellular response to DNA damage stimulus |
| B | 0031060 | biological_process | regulation of histone methylation |
| B | 0035064 | molecular_function | methylated histone binding |
| C | 0006974 | biological_process | cellular response to DNA damage stimulus |
| C | 0031060 | biological_process | regulation of histone methylation |
| C | 0035064 | molecular_function | methylated histone binding |
| D | 0006974 | biological_process | cellular response to DNA damage stimulus |
| D | 0031060 | biological_process | regulation of histone methylation |
| D | 0035064 | molecular_function | methylated histone binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 101 |
| Chain | Residue |
| A | ASP55 |
| A | SER56 |
| A | ALA57 |
| A | ARG58 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:15983376, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16627869, ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| E | M3L36 | |
| F | M3L36 | |
| G | M3L36 | |
| H | M3L36 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-methyllysine => ECO:0000269|PubMed:15983376 |
| Chain | Residue | Details |
| E | LYS37 | |
| F | LYS37 | |
| G | LYS37 | |
| H | LYS37 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000269|PubMed:19783980 |
| Chain | Residue | Details |
| E | TYR41 | |
| F | TYR41 | |
| G | TYR41 | |
| H | TYR41 |
