6W7B
K2P2.1 (TREK-1), 0 mM K+
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005267 | molecular_function | potassium channel activity |
| A | 0016020 | cellular_component | membrane |
| A | 0071805 | biological_process | potassium ion transmembrane transport |
| B | 0005267 | molecular_function | potassium channel activity |
| B | 0016020 | cellular_component | membrane |
| B | 0071805 | biological_process | potassium ion transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 160 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | VAL47-ALA67 | |
| A | ILE157-VAL177 | |
| A | ILE208-VAL228 | |
| A | VAL273-GLY293 | |
| B | VAL47-ALA67 | |
| B | ILE157-VAL177 | |
| B | ILE208-VAL228 | |
| B | VAL273-GLY293 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 52 |
| Details | INTRAMEM: Pore-forming; Name=Pore-forming 1 => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU129-GLY155 | |
| B | LEU129-GLY155 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 58 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY178-ARG207 | |
| B | GLY178-ARG207 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 60 |
| Details | INTRAMEM: Pore-forming; Name=Pore-forming 2 => ECO:0000255 |
| Chain | Residue | Details |
| A | ALA238-ASP268 | |
| B | ALA238-ASP268 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28693035, ECO:0000269|PubMed:33127683, ECO:0007744|PDB:6W7B, ECO:0007744|PDB:6W83 |
| Chain | Residue | Details |
| A | THR142 | |
| B | THR142 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:33127683, ECO:0007744|PDB:6W83 |
| Chain | Residue | Details |
| A | ILE143 | |
| B | ILE252 | |
| B | GLY253 | |
| B | PHE254 | |
| A | GLY144 | |
| A | PHE145 | |
| A | ILE252 | |
| A | GLY253 | |
| A | PHE254 | |
| B | ILE143 | |
| B | GLY144 | |
| B | PHE145 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28693035, ECO:0007744|PDB:6W7B, ECO:0007744|PDB:6W83 |
| Chain | Residue | Details |
| A | THR251 | |
| B | THR251 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | SITE: pH sensor => ECO:0000269|PubMed:19667202, ECO:0000269|PubMed:27035963 |
| Chain | Residue | Details |
| A | HIS126 | |
| B | HIS126 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | SER95 | |
| A | ALA119 | |
| B | SER95 | |
| B | ALA119 |
