6W4N
Co-crystal structure of Pd_dinase with probe glycine-propargylglycine-AOMK
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004177 | molecular_function | aminopeptidase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0006508 | biological_process | proteolysis |
A | 0008234 | molecular_function | cysteine-type peptidase activity |
A | 0009401 | biological_process | phosphoenolpyruvate-dependent sugar phosphotransferase system |
A | 0009636 | biological_process | response to toxic substance |
A | 0016020 | cellular_component | membrane |
A | 0043418 | biological_process | homocysteine catabolic process |
A | 0046872 | molecular_function | metal ion binding |
A | 0070005 | molecular_function | cysteine-type aminopeptidase activity |
B | 0004177 | molecular_function | aminopeptidase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0006508 | biological_process | proteolysis |
B | 0008234 | molecular_function | cysteine-type peptidase activity |
B | 0009401 | biological_process | phosphoenolpyruvate-dependent sugar phosphotransferase system |
B | 0009636 | biological_process | response to toxic substance |
B | 0016020 | cellular_component | membrane |
B | 0043418 | biological_process | homocysteine catabolic process |
B | 0046872 | molecular_function | metal ion binding |
B | 0070005 | molecular_function | cysteine-type aminopeptidase activity |
C | 0004177 | molecular_function | aminopeptidase activity |
C | 0005737 | cellular_component | cytoplasm |
C | 0006508 | biological_process | proteolysis |
C | 0008234 | molecular_function | cysteine-type peptidase activity |
C | 0009401 | biological_process | phosphoenolpyruvate-dependent sugar phosphotransferase system |
C | 0009636 | biological_process | response to toxic substance |
C | 0016020 | cellular_component | membrane |
C | 0043418 | biological_process | homocysteine catabolic process |
C | 0046872 | molecular_function | metal ion binding |
C | 0070005 | molecular_function | cysteine-type aminopeptidase activity |
D | 0004177 | molecular_function | aminopeptidase activity |
D | 0005737 | cellular_component | cytoplasm |
D | 0006508 | biological_process | proteolysis |
D | 0008234 | molecular_function | cysteine-type peptidase activity |
D | 0009401 | biological_process | phosphoenolpyruvate-dependent sugar phosphotransferase system |
D | 0009636 | biological_process | response to toxic substance |
D | 0016020 | cellular_component | membrane |
D | 0043418 | biological_process | homocysteine catabolic process |
D | 0046872 | molecular_function | metal ion binding |
D | 0070005 | molecular_function | cysteine-type aminopeptidase activity |
E | 0004177 | molecular_function | aminopeptidase activity |
E | 0005737 | cellular_component | cytoplasm |
E | 0006508 | biological_process | proteolysis |
E | 0008234 | molecular_function | cysteine-type peptidase activity |
E | 0009401 | biological_process | phosphoenolpyruvate-dependent sugar phosphotransferase system |
E | 0009636 | biological_process | response to toxic substance |
E | 0016020 | cellular_component | membrane |
E | 0043418 | biological_process | homocysteine catabolic process |
E | 0046872 | molecular_function | metal ion binding |
E | 0070005 | molecular_function | cysteine-type aminopeptidase activity |
F | 0004177 | molecular_function | aminopeptidase activity |
F | 0005737 | cellular_component | cytoplasm |
F | 0006508 | biological_process | proteolysis |
F | 0008234 | molecular_function | cysteine-type peptidase activity |
F | 0009401 | biological_process | phosphoenolpyruvate-dependent sugar phosphotransferase system |
F | 0009636 | biological_process | response to toxic substance |
F | 0016020 | cellular_component | membrane |
F | 0043418 | biological_process | homocysteine catabolic process |
F | 0046872 | molecular_function | metal ion binding |
F | 0070005 | molecular_function | cysteine-type aminopeptidase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 10 |
Details | binding site for residue SWJ A 601 |
Chain | Residue |
A | GLN50 |
A | HIS340 |
A | GLY54 |
A | CYS56 |
A | TRP57 |
A | GLY108 |
A | GLY109 |
A | ASP237 |
A | ASP338 |
A | ASP339 |
site_id | AC2 |
Number of Residues | 5 |
Details | binding site for residue K A 602 |
Chain | Residue |
A | ASP271 |
A | SER273 |
A | GLU274 |
A | GLU335 |
A | HOH715 |
site_id | AC3 |
Number of Residues | 4 |
Details | binding site for residue K A 603 |
Chain | Residue |
A | ASP78 |
A | LEU79 |
A | GLU81 |
A | GLU126 |
site_id | AC4 |
Number of Residues | 4 |
Details | binding site for residue K B 602 |
Chain | Residue |
B | ASP78 |
B | LEU79 |
B | GLU81 |
B | GLU126 |
site_id | AC5 |
Number of Residues | 4 |
Details | binding site for residue K B 603 |
Chain | Residue |
B | ASP271 |
B | SER273 |
B | GLU274 |
B | GLU335 |
site_id | AC6 |
Number of Residues | 9 |
Details | binding site for residue SWJ C 601 |
Chain | Residue |
C | GLN50 |
C | GLY54 |
C | CYS56 |
C | TRP57 |
C | GLY108 |
C | GLY109 |
C | ASP237 |
C | ASP338 |
C | ASP339 |
site_id | AC7 |
Number of Residues | 4 |
Details | binding site for residue K C 602 |
Chain | Residue |
C | ASP271 |
C | SER273 |
C | GLU274 |
C | GLU335 |
site_id | AC8 |
Number of Residues | 5 |
Details | binding site for residue K C 603 |
Chain | Residue |
C | GLU66 |
C | ASP78 |
C | LEU79 |
C | GLU81 |
C | GLU126 |
site_id | AC9 |
Number of Residues | 4 |
Details | binding site for residue K D 602 |
Chain | Residue |
D | ASP78 |
D | LEU79 |
D | GLU81 |
D | GLU126 |
site_id | AD1 |
Number of Residues | 4 |
Details | binding site for residue K D 603 |
Chain | Residue |
D | ASP271 |
D | SER273 |
D | GLU274 |
D | GLU335 |
site_id | AD2 |
Number of Residues | 5 |
Details | binding site for residue K E 602 |
Chain | Residue |
E | ASP78 |
E | LEU79 |
E | GLU81 |
E | GLU126 |
E | HOH827 |
site_id | AD3 |
Number of Residues | 4 |
Details | binding site for residue K E 603 |
Chain | Residue |
E | ASP271 |
E | SER273 |
E | GLU274 |
E | GLU335 |
site_id | AD4 |
Number of Residues | 5 |
Details | binding site for residue K F 602 |
Chain | Residue |
F | ASP271 |
F | SER273 |
F | GLU274 |
F | GLU335 |
F | HOH715 |
site_id | AD5 |
Number of Residues | 5 |
Details | binding site for residue K F 603 |
Chain | Residue |
F | ASP78 |
F | LEU79 |
F | GLU81 |
F | GLU126 |
F | HOH794 |
site_id | AD6 |
Number of Residues | 14 |
Details | binding site for Di-peptide SWJ B 601 and CYS B 56 |
Chain | Residue |
B | GLN50 |
B | GLY54 |
B | THR55 |
B | TRP57 |
B | CYS58 |
B | TYR59 |
B | SER60 |
B | GLY108 |
B | GLY109 |
B | ASP237 |
B | ASP338 |
B | ASP339 |
B | HIS340 |
B | GLY341 |
site_id | AD7 |
Number of Residues | 14 |
Details | binding site for Di-peptide SWJ D 601 and CYS D 56 |
Chain | Residue |
D | GLY341 |
D | GLN50 |
D | GLY54 |
D | THR55 |
D | TRP57 |
D | CYS58 |
D | TYR59 |
D | SER60 |
D | GLY108 |
D | GLY109 |
D | ASP237 |
D | ASP338 |
D | ASP339 |
D | HIS340 |
site_id | AD8 |
Number of Residues | 10 |
Details | binding site for Di-peptide SWJ D 601 and ASP D 338 |
Chain | Residue |
D | GLN50 |
D | GLY54 |
D | THR55 |
D | CYS56 |
D | GLY108 |
D | GLY109 |
D | ASP237 |
D | THR337 |
D | ASP339 |
D | HIS340 |
site_id | AD9 |
Number of Residues | 15 |
Details | binding site for Di-peptide SWJ E 601 and CYS E 56 |
Chain | Residue |
E | GLN50 |
E | GLY54 |
E | THR55 |
E | TRP57 |
E | CYS58 |
E | TYR59 |
E | SER60 |
E | GLY108 |
E | GLY109 |
E | ASP237 |
E | ASP338 |
E | ASP339 |
E | HIS340 |
E | GLY341 |
E | HOH702 |
site_id | AE1 |
Number of Residues | 15 |
Details | binding site for Di-peptide SWJ F 601 and CYS F 56 |
Chain | Residue |
F | GLN50 |
F | GLY54 |
F | THR55 |
F | TRP57 |
F | CYS58 |
F | TYR59 |
F | SER60 |
F | GLY108 |
F | GLY109 |
F | ASP237 |
F | ASP338 |
F | ASP339 |
F | HIS340 |
F | GLY341 |
F | HOH704 |
Functional Information from PROSITE/UniProt
site_id | PS00139 |
Number of Residues | 12 |
Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QNrAGTCWCySS |
Chain | Residue | Details |
A | GLN50-SER61 |