6W4L

The crystal structure of a single chain H2B-H2A histone chimera from Xenopus laevis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000786	cellular_component	nucleosome
A	0003677	molecular_function	DNA binding
A	0030527	molecular_function	structural constituent of chromatin
A	0046982	molecular_function	protein heterodimerization activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue PPV A 1201

Chain	Residue
A	HIS50
A	PRO51
A	ASP52
A	THR53
A	LYS121
A	ARG1072
A	HOH1303
A	HOH1316

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Functional Information from PROSITE/UniProt

site_id	PS00046
Number of Residues	7
Details	HISTONE_H2A Histone H2A signature. AGLqFPV

Chain	Residue	Details
A	ALA1022-VAL1028

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site_id	PS00357
Number of Residues	23
Details	HISTONE_H2B Histone H2B signature. REIQTavRlLLpGELaKHAVSEG

Chain	Residue	Details
A	ARG93-GLY115

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	CARBOHYD: O-linked (GlcNAc) serine => ECO:0000250|UniProtKB:P62807

Chain	Residue	Details
A	SER113

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site_id	SWS_FT_FI2
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P0C1H4

Chain	Residue	Details
A	LYS121

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site_id	SWS_FT_FI3
Number of Residues	3
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250

Chain	Residue	Details
A	LYS1014
A	LYS1016

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: N6-(2-hydroxyisobutyryl)lysine; alternate => ECO:0000250|UniProtKB:P0C0S8

Chain	Residue	Details
A	LYS1037

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site_id	SWS_FT_FI5
Number of Residues	2
Details	MOD_RES: N6-(2-hydroxyisobutyryl)lysine => ECO:0000250|UniProtKB:P0C0S8

Chain	Residue	Details
A	LYS1075
A	LYS1076

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site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:P0C0S8

Chain	Residue	Details
A	LYS1096

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site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: N5-methylglutamine => ECO:0000250

Chain	Residue	Details
A	GLN1105

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