6W2Y
CryoEM Structure of GABAB1b Homodimer
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004930 | molecular_function | G protein-coupled receptor activity |
| A | 0004965 | molecular_function | G protein-coupled GABA receptor activity |
| A | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| A | 0016020 | cellular_component | membrane |
| B | 0004930 | molecular_function | G protein-coupled receptor activity |
| B | 0004965 | molecular_function | G protein-coupled GABA receptor activity |
| B | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| B | 0016020 | cellular_component | membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE475-PHE495 | |
| B | PHE475-PHE495 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 318 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN496-ASN514 | |
| A | HIS572-LEU593 | |
| A | GLU673-ALA687 | |
| A | PRO738-LYS844 | |
| B | ASN496-ASN514 | |
| B | HIS572-LEU593 | |
| B | GLU673-ALA687 | |
| B | PRO738-LYS844 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU515-TYR535 | |
| B | LEU515-TYR535 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 114 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| A | HIS536-LEU550 | |
| A | ASP615-THR651 | |
| A | LEU709-ALA716 | |
| B | HIS536-LEU550 | |
| B | ASP615-THR651 | |
| B | LEU709-ALA716 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000255 |
| Chain | Residue | Details |
| A | TRP551-VAL571 | |
| B | TRP551-VAL571 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000255 |
| Chain | Residue | Details |
| A | TYR594-VAL614 | |
| B | TYR594-VAL614 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000255 |
| Chain | Residue | Details |
| A | TRP652-TYR672 | |
| B | TRP652-TYR672 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000255 |
| Chain | Residue | Details |
| A | VAL688-ILE708 | |
| B | VAL688-ILE708 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE717-VAL737 | |
| B | PHE717-VAL737 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:24305054, ECO:0007744|PDB:4MRM |
| Chain | Residue | Details |
| A | SER130 | |
| A | SER153 | |
| A | HIS170 | |
| B | SER130 | |
| B | SER153 | |
| B | HIS170 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:24305054, ECO:0007744|PDB:4MS4 |
| Chain | Residue | Details |
| A | TYR250 | |
| B | TYR250 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:24305054, ECO:0007744|PDB:4MR7 |
| Chain | Residue | Details |
| A | GLU349 | |
| B | GLU349 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q9WV18 |
| Chain | Residue | Details |
| A | THR756 | |
| A | THR813 | |
| B | THR756 | |
| B | THR813 |
| site_id | SWS_FT_FI14 |
| Number of Residues | 8 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | SER84 | |
| A | ASN292 | |
| A | ASN385 | |
| A | ASN397 | |
| B | SER84 | |
| B | ASN292 | |
| B | ASN385 | |
| B | ASN397 |
| site_id | SWS_FT_FI15 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:24305054 |
| Chain | Residue | Details |
| A | ASN323 | |
| A | ASN365 | |
| B | ASN323 | |
| B | ASN365 |
