6VRX
Mucor circinelloides FKBP12 protein bound with FK506 in P3221 space group
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016853 | molecular_function | isomerase activity |
| B | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016853 | molecular_function | isomerase activity |
| C | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0016853 | molecular_function | isomerase activity |
| D | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0016853 | molecular_function | isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue FK5 A 201 |
| Chain | Residue |
| A | TYR27 |
| A | ALA82 |
| A | TYR83 |
| A | TYR88 |
| A | HOH306 |
| B | LYS36 |
| B | PHE37 |
| B | GLY90 |
| A | PHE37 |
| A | ASP38 |
| A | ARG43 |
| A | PHE47 |
| A | GLN55 |
| A | VAL56 |
| A | ILE57 |
| A | TRP60 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | binding site for residue FK5 B 201 |
| Chain | Residue |
| A | GLU32 |
| A | ASN33 |
| A | ASP35 |
| A | GLY90 |
| A | LEU91 |
| B | TYR27 |
| B | PHE37 |
| B | ASP38 |
| B | ARG43 |
| B | PHE47 |
| B | VAL56 |
| B | ILE57 |
| B | TRP60 |
| B | ALA82 |
| B | TYR83 |
| B | PHE100 |
| B | HOH302 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | binding site for residue FK5 C 201 |
| Chain | Residue |
| C | TYR27 |
| C | PHE37 |
| C | ASP38 |
| C | ARG43 |
| C | PHE47 |
| C | VAL56 |
| C | ILE57 |
| C | TRP60 |
| C | ALA82 |
| C | TYR83 |
| C | TYR88 |
| C | PHE100 |
| D | ASN33 |
| D | ASP35 |
| D | PHE37 |
| D | LEU91 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | binding site for residue FK5 D 201 |
| Chain | Residue |
| C | PRO89 |
| C | GLY90 |
| C | LEU91 |
| D | TYR27 |
| D | PHE37 |
| D | ASP38 |
| D | ARG43 |
| D | PHE47 |
| D | GLN55 |
| D | VAL56 |
| D | ILE57 |
| D | TRP60 |
| D | ALA82 |
| D | TYR83 |
| D | ARG86 |
| D | TYR88 |
| D | GLY90 |
| D | LEU91 |
| D | PHE100 |
