6VQ7

Mammalian V-ATPase from rat brain - composite model of rotational state 2 bound to ADP and SidK (built from focused refinement models)

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
a	0005737	cellular_component	cytoplasm
a	0005886	cellular_component	plasma membrane
a	0007035	biological_process	vacuolar acidification
a	0008150	biological_process	biological_process
a	0016020	cellular_component	membrane
a	0016241	biological_process	regulation of macroautophagy
a	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
a	0030665	cellular_component	clathrin-coated vesicle membrane
a	0030672	cellular_component	synaptic vesicle membrane
a	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
a	0042470	cellular_component	melanosome
a	0043195	cellular_component	terminal bouton
a	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
a	0048471	cellular_component	perinuclear region of cytoplasm
a	0051117	molecular_function	ATPase binding
a	0097401	biological_process	synaptic vesicle lumen acidification
a	1902600	biological_process	proton transmembrane transport
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0016887	molecular_function	ATP hydrolysis activity
A	0030665	cellular_component	clathrin-coated vesicle membrane
A	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
A	0042592	biological_process	homeostatic process
A	0046034	biological_process	ATP metabolic process
A	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
A	1902600	biological_process	proton transmembrane transport
b	0015078	molecular_function	proton transmembrane transporter activity
b	0016020	cellular_component	membrane
b	0030665	cellular_component	clathrin-coated vesicle membrane
b	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
b	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
b	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
b	1902600	biological_process	proton transmembrane transport
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0016887	molecular_function	ATP hydrolysis activity
B	0030665	cellular_component	clathrin-coated vesicle membrane
B	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
B	0042592	biological_process	homeostatic process
B	0046034	biological_process	ATP metabolic process
B	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
B	1902600	biological_process	proton transmembrane transport
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0016887	molecular_function	ATP hydrolysis activity
C	0030665	cellular_component	clathrin-coated vesicle membrane
C	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
C	0042592	biological_process	homeostatic process
C	0046034	biological_process	ATP metabolic process
C	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
C	1902600	biological_process	proton transmembrane transport
d	0005765	cellular_component	lysosomal membrane
d	0030665	cellular_component	clathrin-coated vesicle membrane
d	0033176	cellular_component	proton-transporting V-type ATPase complex
d	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
d	0042592	biological_process	homeostatic process
d	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
d	1902600	biological_process	proton transmembrane transport
D	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
D	0001726	cellular_component	ruffle
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0005902	cellular_component	microvillus
D	0007035	biological_process	vacuolar acidification
D	0016324	cellular_component	apical plasma membrane
D	0019725	biological_process	cellular homeostasis
D	0030665	cellular_component	clathrin-coated vesicle membrane
D	0030672	cellular_component	synaptic vesicle membrane
D	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
D	0042470	cellular_component	melanosome
D	0046034	biological_process	ATP metabolic process
D	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
D	0097401	biological_process	synaptic vesicle lumen acidification
D	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
D	1902600	biological_process	proton transmembrane transport
e	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
e	0016020	cellular_component	membrane
e	0030665	cellular_component	clathrin-coated vesicle membrane
e	0030672	cellular_component	synaptic vesicle membrane
e	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
e	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
e	0097401	biological_process	synaptic vesicle lumen acidification
e	1902600	biological_process	proton transmembrane transport
E	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
E	0001726	cellular_component	ruffle
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0005902	cellular_component	microvillus
E	0007035	biological_process	vacuolar acidification
E	0016324	cellular_component	apical plasma membrane
E	0019725	biological_process	cellular homeostasis
E	0030665	cellular_component	clathrin-coated vesicle membrane
E	0030672	cellular_component	synaptic vesicle membrane
E	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
E	0042470	cellular_component	melanosome
E	0046034	biological_process	ATP metabolic process
E	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
E	0097401	biological_process	synaptic vesicle lumen acidification
E	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
E	1902600	biological_process	proton transmembrane transport
f	0004521	molecular_function	RNA endonuclease activity
f	0016020	cellular_component	membrane
f	0090304	biological_process	nucleic acid metabolic process
F	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
F	0001726	cellular_component	ruffle
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0005902	cellular_component	microvillus
F	0007035	biological_process	vacuolar acidification
F	0016324	cellular_component	apical plasma membrane
F	0019725	biological_process	cellular homeostasis
F	0030665	cellular_component	clathrin-coated vesicle membrane
F	0030672	cellular_component	synaptic vesicle membrane
F	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
F	0042470	cellular_component	melanosome
F	0046034	biological_process	ATP metabolic process
F	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
F	0097401	biological_process	synaptic vesicle lumen acidification
F	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
F	1902600	biological_process	proton transmembrane transport
g	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
g	0005765	cellular_component	lysosomal membrane
g	0008021	cellular_component	synaptic vesicle
g	0015078	molecular_function	proton transmembrane transporter activity
g	0016020	cellular_component	membrane
g	0030177	biological_process	positive regulation of Wnt signaling pathway
g	0030665	cellular_component	clathrin-coated vesicle membrane
g	0030672	cellular_component	synaptic vesicle membrane
g	0031625	molecular_function	ubiquitin protein ligase binding
g	0033176	cellular_component	proton-transporting V-type ATPase complex
g	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
g	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
g	0046611	cellular_component	lysosomal proton-transporting V-type ATPase complex
g	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
g	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
g	0071230	biological_process	cellular response to amino acid stimulus
g	0097401	biological_process	synaptic vesicle lumen acidification
g	0098588	cellular_component	bounding membrane of organelle
g	0160124	molecular_function	guanyl nucleotide exchange factor activator activity
g	1902600	biological_process	proton transmembrane transport
g	1904093	biological_process	negative regulation of autophagic cell death
g	1904263	biological_process	positive regulation of TORC1 signaling
G	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
G	0005886	cellular_component	plasma membrane
G	0008150	biological_process	biological_process
G	0015078	molecular_function	proton transmembrane transporter activity
G	0016020	cellular_component	membrane
G	0030665	cellular_component	clathrin-coated vesicle membrane
G	0030672	cellular_component	synaptic vesicle membrane
G	0033176	cellular_component	proton-transporting V-type ATPase complex
G	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
G	0045177	cellular_component	apical part of cell
G	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
G	0097401	biological_process	synaptic vesicle lumen acidification
G	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
G	1902600	biological_process	proton transmembrane transport
h	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
h	0005765	cellular_component	lysosomal membrane
h	0008021	cellular_component	synaptic vesicle
h	0015078	molecular_function	proton transmembrane transporter activity
h	0016020	cellular_component	membrane
h	0030177	biological_process	positive regulation of Wnt signaling pathway
h	0030665	cellular_component	clathrin-coated vesicle membrane
h	0030672	cellular_component	synaptic vesicle membrane
h	0031625	molecular_function	ubiquitin protein ligase binding
h	0033176	cellular_component	proton-transporting V-type ATPase complex
h	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
h	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
h	0046611	cellular_component	lysosomal proton-transporting V-type ATPase complex
h	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
h	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
h	0071230	biological_process	cellular response to amino acid stimulus
h	0097401	biological_process	synaptic vesicle lumen acidification
h	0098588	cellular_component	bounding membrane of organelle
h	0160124	molecular_function	guanyl nucleotide exchange factor activator activity
h	1902600	biological_process	proton transmembrane transport
h	1904093	biological_process	negative regulation of autophagic cell death
h	1904263	biological_process	positive regulation of TORC1 signaling
H	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
i	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
i	0005765	cellular_component	lysosomal membrane
i	0008021	cellular_component	synaptic vesicle
i	0015078	molecular_function	proton transmembrane transporter activity
i	0016020	cellular_component	membrane
i	0030177	biological_process	positive regulation of Wnt signaling pathway
i	0030665	cellular_component	clathrin-coated vesicle membrane
i	0030672	cellular_component	synaptic vesicle membrane
i	0031625	molecular_function	ubiquitin protein ligase binding
i	0033176	cellular_component	proton-transporting V-type ATPase complex
i	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
i	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
i	0046611	cellular_component	lysosomal proton-transporting V-type ATPase complex
i	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
i	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
i	0071230	biological_process	cellular response to amino acid stimulus
i	0097401	biological_process	synaptic vesicle lumen acidification
i	0098588	cellular_component	bounding membrane of organelle
i	0160124	molecular_function	guanyl nucleotide exchange factor activator activity
i	1902600	biological_process	proton transmembrane transport
i	1904093	biological_process	negative regulation of autophagic cell death
i	1904263	biological_process	positive regulation of TORC1 signaling
I	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
I	0005737	cellular_component	cytoplasm
I	0005765	cellular_component	lysosomal membrane
I	0005768	cellular_component	endosome
I	0005829	cellular_component	cytosol
I	0005902	cellular_component	microvillus
I	0016324	cellular_component	apical plasma membrane
I	0030665	cellular_component	clathrin-coated vesicle membrane
I	0030672	cellular_component	synaptic vesicle membrane
I	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
I	0046611	cellular_component	lysosomal proton-transporting V-type ATPase complex
I	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
I	0051117	molecular_function	ATPase binding
I	0071230	biological_process	cellular response to amino acid stimulus
I	0097401	biological_process	synaptic vesicle lumen acidification
I	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
I	0160124	molecular_function	guanyl nucleotide exchange factor activator activity
I	1902600	biological_process	proton transmembrane transport
I	1904263	biological_process	positive regulation of TORC1 signaling
j	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
j	0005765	cellular_component	lysosomal membrane
j	0008021	cellular_component	synaptic vesicle
j	0015078	molecular_function	proton transmembrane transporter activity
j	0016020	cellular_component	membrane
j	0030177	biological_process	positive regulation of Wnt signaling pathway
j	0030665	cellular_component	clathrin-coated vesicle membrane
j	0030672	cellular_component	synaptic vesicle membrane
j	0031625	molecular_function	ubiquitin protein ligase binding
j	0033176	cellular_component	proton-transporting V-type ATPase complex
j	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
j	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
j	0046611	cellular_component	lysosomal proton-transporting V-type ATPase complex
j	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
j	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
j	0071230	biological_process	cellular response to amino acid stimulus
j	0097401	biological_process	synaptic vesicle lumen acidification
j	0098588	cellular_component	bounding membrane of organelle
j	0160124	molecular_function	guanyl nucleotide exchange factor activator activity
j	1902600	biological_process	proton transmembrane transport
j	1904093	biological_process	negative regulation of autophagic cell death
j	1904263	biological_process	positive regulation of TORC1 signaling
J	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
J	0005737	cellular_component	cytoplasm
J	0005765	cellular_component	lysosomal membrane
J	0005768	cellular_component	endosome
J	0005829	cellular_component	cytosol
J	0005902	cellular_component	microvillus
J	0016324	cellular_component	apical plasma membrane
J	0030665	cellular_component	clathrin-coated vesicle membrane
J	0030672	cellular_component	synaptic vesicle membrane
J	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
J	0046611	cellular_component	lysosomal proton-transporting V-type ATPase complex
J	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
J	0051117	molecular_function	ATPase binding
J	0071230	biological_process	cellular response to amino acid stimulus
J	0097401	biological_process	synaptic vesicle lumen acidification
J	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
J	0160124	molecular_function	guanyl nucleotide exchange factor activator activity
J	1902600	biological_process	proton transmembrane transport
J	1904263	biological_process	positive regulation of TORC1 signaling
k	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
k	0005765	cellular_component	lysosomal membrane
k	0008021	cellular_component	synaptic vesicle
k	0015078	molecular_function	proton transmembrane transporter activity
k	0016020	cellular_component	membrane
k	0030177	biological_process	positive regulation of Wnt signaling pathway
k	0030665	cellular_component	clathrin-coated vesicle membrane
k	0030672	cellular_component	synaptic vesicle membrane
k	0031625	molecular_function	ubiquitin protein ligase binding
k	0033176	cellular_component	proton-transporting V-type ATPase complex
k	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
k	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
k	0046611	cellular_component	lysosomal proton-transporting V-type ATPase complex
k	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
k	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
k	0071230	biological_process	cellular response to amino acid stimulus
k	0097401	biological_process	synaptic vesicle lumen acidification
k	0098588	cellular_component	bounding membrane of organelle
k	0160124	molecular_function	guanyl nucleotide exchange factor activator activity
k	1902600	biological_process	proton transmembrane transport
k	1904093	biological_process	negative regulation of autophagic cell death
k	1904263	biological_process	positive regulation of TORC1 signaling
K	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
K	0005737	cellular_component	cytoplasm
K	0005765	cellular_component	lysosomal membrane
K	0005768	cellular_component	endosome
K	0005829	cellular_component	cytosol
K	0005902	cellular_component	microvillus
K	0016324	cellular_component	apical plasma membrane
K	0030665	cellular_component	clathrin-coated vesicle membrane
K	0030672	cellular_component	synaptic vesicle membrane
K	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
K	0046611	cellular_component	lysosomal proton-transporting V-type ATPase complex
K	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
K	0051117	molecular_function	ATPase binding
K	0071230	biological_process	cellular response to amino acid stimulus
K	0097401	biological_process	synaptic vesicle lumen acidification
K	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
K	0160124	molecular_function	guanyl nucleotide exchange factor activator activity
K	1902600	biological_process	proton transmembrane transport
K	1904263	biological_process	positive regulation of TORC1 signaling
l	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
l	0005765	cellular_component	lysosomal membrane
l	0008021	cellular_component	synaptic vesicle
l	0015078	molecular_function	proton transmembrane transporter activity
l	0016020	cellular_component	membrane
l	0030177	biological_process	positive regulation of Wnt signaling pathway
l	0030665	cellular_component	clathrin-coated vesicle membrane
l	0030672	cellular_component	synaptic vesicle membrane
l	0031625	molecular_function	ubiquitin protein ligase binding
l	0033176	cellular_component	proton-transporting V-type ATPase complex
l	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
l	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
l	0046611	cellular_component	lysosomal proton-transporting V-type ATPase complex
l	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
l	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
l	0071230	biological_process	cellular response to amino acid stimulus
l	0097401	biological_process	synaptic vesicle lumen acidification
l	0098588	cellular_component	bounding membrane of organelle
l	0160124	molecular_function	guanyl nucleotide exchange factor activator activity
l	1902600	biological_process	proton transmembrane transport
l	1904093	biological_process	negative regulation of autophagic cell death
l	1904263	biological_process	positive regulation of TORC1 signaling
L	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
L	0015078	molecular_function	proton transmembrane transporter activity
L	0016020	cellular_component	membrane
L	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
L	0030665	cellular_component	clathrin-coated vesicle membrane
L	0030672	cellular_component	synaptic vesicle membrane
L	0033176	cellular_component	proton-transporting V-type ATPase complex
L	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
L	0034220	biological_process	monoatomic ion transmembrane transport
L	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
L	0097401	biological_process	synaptic vesicle lumen acidification
L	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
L	1902600	biological_process	proton transmembrane transport
m	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
m	0005765	cellular_component	lysosomal membrane
m	0008021	cellular_component	synaptic vesicle
m	0015078	molecular_function	proton transmembrane transporter activity
m	0016020	cellular_component	membrane
m	0030177	biological_process	positive regulation of Wnt signaling pathway
m	0030665	cellular_component	clathrin-coated vesicle membrane
m	0030672	cellular_component	synaptic vesicle membrane
m	0031625	molecular_function	ubiquitin protein ligase binding
m	0033176	cellular_component	proton-transporting V-type ATPase complex
m	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
m	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
m	0046611	cellular_component	lysosomal proton-transporting V-type ATPase complex
m	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
m	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
m	0071230	biological_process	cellular response to amino acid stimulus
m	0097401	biological_process	synaptic vesicle lumen acidification
m	0098588	cellular_component	bounding membrane of organelle
m	0160124	molecular_function	guanyl nucleotide exchange factor activator activity
m	1902600	biological_process	proton transmembrane transport
m	1904093	biological_process	negative regulation of autophagic cell death
m	1904263	biological_process	positive regulation of TORC1 signaling
M	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
M	0012505	cellular_component	endomembrane system
M	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
M	0030672	cellular_component	synaptic vesicle membrane
M	0042470	cellular_component	melanosome
M	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
M	0097401	biological_process	synaptic vesicle lumen acidification
M	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
M	1902600	biological_process	proton transmembrane transport
n	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
n	0005765	cellular_component	lysosomal membrane
n	0008021	cellular_component	synaptic vesicle
n	0015078	molecular_function	proton transmembrane transporter activity
n	0016020	cellular_component	membrane
n	0030177	biological_process	positive regulation of Wnt signaling pathway
n	0030665	cellular_component	clathrin-coated vesicle membrane
n	0030672	cellular_component	synaptic vesicle membrane
n	0031625	molecular_function	ubiquitin protein ligase binding
n	0033176	cellular_component	proton-transporting V-type ATPase complex
n	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
n	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
n	0046611	cellular_component	lysosomal proton-transporting V-type ATPase complex
n	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
n	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
n	0071230	biological_process	cellular response to amino acid stimulus
n	0097401	biological_process	synaptic vesicle lumen acidification
n	0098588	cellular_component	bounding membrane of organelle
n	0160124	molecular_function	guanyl nucleotide exchange factor activator activity
n	1902600	biological_process	proton transmembrane transport
n	1904093	biological_process	negative regulation of autophagic cell death
n	1904263	biological_process	positive regulation of TORC1 signaling
N	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
N	0012505	cellular_component	endomembrane system
N	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
N	0030672	cellular_component	synaptic vesicle membrane
N	0042470	cellular_component	melanosome
N	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
N	0097401	biological_process	synaptic vesicle lumen acidification
N	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
N	1902600	biological_process	proton transmembrane transport
o	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
o	0005765	cellular_component	lysosomal membrane
o	0008021	cellular_component	synaptic vesicle
o	0015078	molecular_function	proton transmembrane transporter activity
o	0016020	cellular_component	membrane
o	0030177	biological_process	positive regulation of Wnt signaling pathway
o	0030665	cellular_component	clathrin-coated vesicle membrane
o	0030672	cellular_component	synaptic vesicle membrane
o	0031625	molecular_function	ubiquitin protein ligase binding
o	0033176	cellular_component	proton-transporting V-type ATPase complex
o	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
o	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
o	0046611	cellular_component	lysosomal proton-transporting V-type ATPase complex
o	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
o	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
o	0071230	biological_process	cellular response to amino acid stimulus
o	0097401	biological_process	synaptic vesicle lumen acidification
o	0098588	cellular_component	bounding membrane of organelle
o	0160124	molecular_function	guanyl nucleotide exchange factor activator activity
o	1902600	biological_process	proton transmembrane transport
o	1904093	biological_process	negative regulation of autophagic cell death
o	1904263	biological_process	positive regulation of TORC1 signaling
O	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
O	0012505	cellular_component	endomembrane system
O	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
O	0030672	cellular_component	synaptic vesicle membrane
O	0042470	cellular_component	melanosome
O	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
O	0097401	biological_process	synaptic vesicle lumen acidification
O	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
O	1902600	biological_process	proton transmembrane transport
p	0016020	cellular_component	membrane
p	0038023	molecular_function	signaling receptor activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	binding site for residue ADP B 701

Chain	Residue
B	ALA251
B	GLN522
B	GLY524
B	TYR525
B	MG702
E	ARG400
E	LYS403
B	PHE252
B	GLY253
B	CYS254
B	GLY255
B	LYS256
B	THR257
B	VAL258
B	PHE445

---

site_id	AC2
Number of Residues	3
Details	binding site for residue MG B 702

Chain	Residue
B	THR257
B	GLU279
B	ADP701

---

Functional Information from PROSITE/UniProt

site_id	PS00152
Number of Residues	10
Details	ATPASE_ALPHA_BETA ATP synthase alpha and beta subunits signature. PSVNWLISYS

Chain	Residue	Details
A	PRO446-SER455
D	PRO390-SER399

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI10
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"32165585","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"6VQ6","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"6VQ9","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"6VQ7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6VQ8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6VQA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6VQB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	Modified residue: {"description":"N-acetylthreonine","evidences":[{"source":"UniProtKB","id":"P21283","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	3
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"UniProtKB","id":"P36543","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	3
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P50518","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	1010
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	128
Details	Topological domain: {"description":"Vacuolar","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	364
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q9Z1G4","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q93050","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q9Z1G4","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	6
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"24090084","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	153
Details	Topological domain: {"description":"Lumenal","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	9
Details	Site: {"description":"Essential for proton translocation","evidences":[{"source":"PubMed","id":"32165585","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---